Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

cysH from Mycobacterium tuberculosis H37Ra

Victor ID 1872
Gene Name cysH from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5213172
NCBI Protein GI 148662225
Locus Tag MRA_2416
Protein Accession YP_001283748.1
Other Database IDs UniProtKB-ID: CYSH_MYCTA
UniRef100: UniRef100_A1KL82
UniRef90: UniRef90_A1KL82
UniRef50: UniRef50_A1KL82
UniParc: UPI0000128CEC
EMBL: CP000611
EMBL-CDS: ABQ74186.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000065086
EnsemblGenome_TRS: EBMYCT00000065091
EnsemblGenome_PRO: EBMYCP00000063201
GenomeReviews: CP000611_GR
KEGG: mra:MRA_2416
eggNOG: COG0175
HOGENOM: HBG758022
OMA: FEETLAY
ProtClustDB: PRK02090
BioCyc: MTUB419947:MRA_2416-MONOMER
Taxonomy ID 419947
Gene Starting Position 2698334
Gene Ending Position 2699098
Gene Strand (Orientation) +
Protein Name phosphoadenosine phosphosulfate reductase
DNA Sequence 
>gi|148659757:2698334-2699098 Mycobacterium tuberculosis H37Ra, complete genome
GATGAGCGGCGAGACAACCAGGCTGACCGAACCGCAACTACGTGAGCTGGCCGCGCGCGGAGCTGCCGAA
CTCGACGGCGCCACCGCCACCGACATGTTGCGCTGGACCGACGAAACCTTCGGCGACATCGGCGGCGCCG
GCGGCGGCGTGAGCGGACATCGCGGGTGGACAACGTGCAACTACGTAGTTGCTTCCAACATGGCTGATGC
GGTGCTGGTGGATCTGGCCGCCAAGGTGCGACCGGGCGTACCGGTCATCTTTCTTGATACCGGCTACCAC
TTCGTCGAAACAATCGGCACCAGAGATGCGATCGAGTCCGTCTATGACGTCCGGGTGCTCAATGTCACTC
CGGAGCACACAGTGGCCGAGCAGGACGAACTGCTGGGCAAGGACTTGTTCGCCCGCAACCCCCATGAATG
CTGCCGGTTGCGCAAGGTCGTTCCCCTGGGCAAGACGCTGCGTGGCTACTCCGCGTGGGTGACCGGGCTA
CGGCGGGTCGATGCACCGACCCGGGCCAATGCCCCGCTGGTCAGCTTCGATGAGACGTTCAAACTAGTGA
AGGTCAACCCGCTGGCGGCGTGGACCGACCAAGATGTGCAGGAATACATTGCCGACAACGACGTGCTGGT
TAATCCGCTTGTGCGGGAAGGCTATCCGTCGATCGGTTGCGCTCCGTGCACAGCCAAACCCGCCGAAGGC
GCCGACCCGCGCAGCGGACGCTGGCAGGGGCTGGCCAAGACCGAATGCGGGTTGCACGCCTCGTG
Protein Sequence 
>gi|148662225|ref|YP_001283748.1| phosphoadenosine phosphosulfate reductase [Mycobacterium tuberculosis H37Ra] MSGETTRLTEPQLRELAARGAAELDGATATDMLRWTDETFGDIGGAGGGVSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIGTRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDVQEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTECGLHAS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cysH mutant is attenuated in mice (Senaratne et al., 2006).
COG COG0175EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Senaratne et al., 2006: Senaratne RH, De Silva AD, Williams SJ, Mougous JD, Reader JR, Zhang T, Chan S, Sidders B, Lee DH, Chan J, Bertozzi CR, Riley LW. 5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Molecular microbiology. 2006; 59(6); 1744-1753. [PubMed: 16553880].