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lspA from Mycobacterium tuberculosis H37Rv

Victor ID 187
Gene Name lspA from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886408
NCBI Protein GI 15608677
Locus Tag Rv1539
Protein Accession NP_216055.1
Other Database IDs UniProtKB-ID: LSPA_MYCTU
UniRef100: UniRef100_A1KIW9
UniRef90: UniRef90_A1KIW9
UniRef50: UniRef50_A1KIW9
UniParc: UPI000012E97D
EMBL: BX842577
EMBL: AE000516
EMBL-CDS: CAA98323.1
EMBL-CDS: AAK45857.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
MEROPS: A08.001
EnsemblGenome: EBMYCG00000000179
EnsemblGenome_TRS: EBMYCT00000000179
EnsemblGenome_PRO: EBMYCP00000000179
EnsemblGenome: EBMYCG00000072853
EnsemblGenome_TRS: EBMYCT00000072858
EnsemblGenome_PRO: EBMYCP00000070917
GenomeReviews: AE000516_
Taxonomy ID 83332
Gene Starting Position 1742243
Gene Ending Position 1742851
Gene Strand (Orientation) +
Protein Name lipoprotein signal peptidase
DNA Sequence 
>gi|57116681:1742243-1742851 Mycobacterium tuberculosis H37Rv, complete genome
TGTGCCTGACGAACCAACAGGATCGGCTGATCCGCTGACCTCGACCGAGGAAGCCGGGGGGGCGGGGGAA
CCTAACGCTCCCGCGCCGCCGCGACGGCTGCGCATGCTGCTGTCGGTCGCTGTGGTGGTGCTCACACTCG
ACATTGTCACCAAGGTGGTAGCTGTCCAACTGTTGCCGCCCGGCCAGCCGGTGTCGATTATCGGCGACAC
GGTGACCTGGACTCTGGTGCGTAATTCTGGGGCGGCCTTCTCGATGGCGACCGGATACACCTGGGTTTTG
ACGCTGATTGCGACGGGTGTCGTGGTCGGAATTTTCTGGATGGGGCGGCGGCTGGTATCGCCGTGGTGGG
CGCTGGGTCTTGGGATGATCCTGGGCGGTGCCATGGGCAACCTGGTTGATCGCTTCTTTCGGGCACCGGG
GCCGCTGCGCGGGCACGTCGTCGATTTCTTGTCGGTCGGCTGGTGGCCGGTGTTCAATGTCGCCGATCCG
TCGGTAGTCGGTGGCGCCATCCTGCTGGTCATCCTGTCGATCTTTGGCTTTGACTTCGACACCGTAGGTC
GGCGACACGCCGACGGGGACACCGTAGGTCGGCGCAAAGCCGATGGCTG
Protein Sequence 
>gi|15608677|ref|NP_216055.1| lipoprotein signal peptidase [Mycobacterium tuberculosis H37Rv] MPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLSVAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lspA mutant is attenuated in mice (Rampini et al., 2008).
COG COG0597MU, under M: Cell wall/membrane/envelope biogenesis; U: Intracellular trafficking, secretion, and vesicular transport
References
Rampini et al., 2008: Rampini SK, Selchow P, Keller C, Ehlers S, Böttger EC, Sander P. LspA inactivation in Mycobacterium tuberculosis results in attenuation without affecting phagosome maturation arrest. Microbiology (Reading, England). 2008; 154(Pt 10); 2991-3001. [PubMed: 18832305].