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hspX from Mycobacterium tuberculosis H37Ra

Victor ID 1862
Gene Name hspX from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5212340
NCBI Protein GI 148661845
Locus Tag MRA_2046
Protein Accession YP_001283368.1
Other Database IDs UniProtKB-ID: A5U456_MYCTA
UniRef100: UniRef100_P0A5B8
UniRef90: UniRef90_P0A5B8
UniRef50: UniRef50_P0A5B8
UniParc: UPI000004A4BF
EMBL: CP000611
EMBL-CDS: ABQ73806.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000067389.
EnsemblGenome_TRS: EBMYCT00000067394
EnsemblGenome_PRO: EBMYCP00000065504
GenomeReviews: CP000611_GR
KEGG: mra:MRA_2046
eggNOG: COG0071
HOGENOM: HBG748242
OMA: DGKYELQ
ProtClustDB: CLSK791576
BioCyc: MTUB419947:MRA_2046-MONOMER
Taxonomy ID 419947
Gene Starting Position 2288397
Gene Ending Position 2288831
Gene Strand (Orientation) -
Protein Name antigen Hsp20
DNA Sequence 
>gi|148659757:2288397-2288831 Mycobacterium tuberculosis H37Ra, complete genome
GTCAGTTGGTGGACCGGATCTGAATGTGCTTTTCGGTTGGCTTCCCTTCCGAAACCGCCACCGACACAGT
AAGAATGCCCTTGTCGTAGGTGGCCTTAATGTCGTCCTCGTCAGCACCTACCGGCAGCGACACCGTGCGA
ACGAAGGAACCGTACGCGAATTCCGAGCGACCGTCGAAGTCCTTCTGCTCGGTGCGCTCGGCCTTGATGG
TCAGCTGACCATCGCGGACCATAATGTCGACGTCCTTGTCGGGGTCGACCCCGGGAAGCTCCGCGCGTAC
CTCGTAGCGCCCCTCTTTCATCTCGTCTTCCAGCCGCATCAACCGGGTGTCGAAGGTGGGCCGGAGTCCG
GCGAATGACGGGAAGGCCGCGAACAGCTCAGAAAACTCGGGGAAGAGGGACCGCGGGTGGCGCTGAACGG
GAAGGGTGGTGGCCA
Protein Sequence 
>gi|148661845|ref|YP_001283368.1| antigen Hsp20 [Mycobacterium tuberculosis H37Ra] MATTLPVQRHPRSLFPEFSELFAAFPSFAGLRPTFDTRLMRLEDEMKEGRYEVRAELPGVDPDKDVDIMVRDGQLTIKAERTEQKDFDGRSEFAYGSFVRTVSLPVGADEDDIKATYDKGILTVSVAVSEGKPTEKHIQIRSTN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hspX mutant is attenuated in murine macrophages and THP-1 cells (Yuan et al., 1998).
COG COG0071O, under O: Posttranslational modification, protein turnover, chaperones
References
Yuan et al., 1998: Yuan Y, Crane DD, Simpson RM, Zhu YQ, Hickey MJ, Sherman DR, Barry CE 3rd. The 16-kDa alpha-crystallin (Acr) protein of Mycobacterium tuberculosis is required for growth in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 1998; 95(16); 9578-9583. [PubMed: 9689123].