Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

plcB from Mycobacterium tuberculosis H37Ra

Victor ID 1859
Gene Name plcB from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5212286
NCBI Protein GI 148662178
Locus Tag MRA_2370
Protein Accession YP_001283701.1
Other Database IDs UniProtKB-ID: A5U539_MYCTA
UniRef100: UniRef100_P95246
UniRef90: UniRef90_P95246
UniRef50: UniRef50_P95246
UniParc: UPI00001650EC
EMBL: CP000611
EMBL-CDS: ABQ74139.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000067474.
EnsemblGenome_TRS: EBMYCT00000067479
EnsemblGenome_PRO: EBMYCP00000065589
GenomeReviews: CP000611_GR
KEGG: mra:MRA_2370
eggNOG: COG3511
HOGENOM: HBG565180
OMA: KAGISWQ
ProtClustDB: CLSK791798
BioCyc: MTUB419947:MRA_2370-MONOMER
Taxonomy ID 419947
Gene Starting Position 2638684
Gene Ending Position 2640222
Gene Strand (Orientation) -
Protein Name membrane-associated phospholipase C 2
DNA Sequence 
>gi|148659757:2638684-2640222 Mycobacterium tuberculosis H37Ra, complete genome
GTCAACAGAGACCGCTGGGAATCCCCCGAGTGGGTGCGGTTTCTTGGGTGGGCATCGACTGTGGGAATGG
CACCCGATAGGGAATTGCCGTCTTGGTCACCGTTCCCAGTACTGCGTTGGGCACGCACTGCGGCAACTTC
GGAAGCGCATTGAGCCGCGGGTGGTCCAGATTGGGTTTCGACGGGTTCGGCGGAGCGGCGAAGTTGAACG
TCGAAGTCATATCGCCGACCGTCGCGTCCCGCCAAGCGGTGAGATTGGGAACCGGGACGCCGAACCGCGC
GCGGATGAGCTTCAGCGTTGACGTGTGATCGAAGGTGTCGTGGACCATCAGTGGGCCGCGGCTATAGGGA
GAGATGACGAGGCAAGGGACGCGAAACCCCAGACCGATCGGCCCACGAATGCCACCCGAGCCGGGCACCG
AGTCGATGTCGGGGACCGTGACGAATTCGCCGGGCGTCCCCGGCGGCGGTGTCGGCGGCACGACGTGGTC
GAAGAACCCGCCGTTCTCGTCGTAGTTGACGATCAGCGCGGTCTTTTCCCACACCGCAGGGTTGGACAGC
AAGATCCGCAGTGCATCGACAATTGCAACGGCGCCGACGTTCACCGGGAATGCGGGATGTTCGGACAGCA
GAAACCCGGGCAGCACCCAGGAGACCTTGGGTAATCGGTTGTTTCTGACGTCGGCGGCGAAGTCCAGCGG
GTAGGTCGGTGAGATGCCGAAACGGGCCAGATTCGACCTCGGATCCGCGGCCTGCTTGAAGTCATTGACC
AGCCCGTTGTAGCCGACGACGGTGTTGTTGAGAGCCCCCAGCAATTTGTTTTGGTACACCTTCCAGCTGA
CCCCGGCATCTTCGAGGTTCTCCGGCATGATGCGCCAGCTGTAGTGCTGCAGAGGTTGGATATTGGGCTC
GATCAGCACCGGCCCGCCGTCAGTGCCGTCGGGGTCGATCCAGGCGCTCATCCAGTAGAGCCGGTTGGGC
GTGGTCCCGCCCAGCAGCGAGCAAAAATAGCCGTCGCAGACCGTGAACGTGTCGGCTAGCAGGTAGTGAA
TGGGCAGGTCACGACGCGTGTAGAAACCCATCGTGACCGGCACGTTGCCCTGCAACGGACTGAACGGGAC
CTGCGCCGGCAGCCAGTTGTCGTTGGCGCCGCCGTTCCACGAGTTGTGCATGCCGATCCAGCTGTGGTCC
GGGTCGTTGACGCATTCGCCGGCGACCAGCGGGCCCCGGGTGGTGTCGAAGCGATATGGAAGGGTGACGC
CGGCGGGGTCAACCGCCTGTGTCATCGGGTTCCAGCCCGACTGCGCGAATACCACCGGCGGGGTGGTGTC
ATCGAACCCGCGGGTGTCAGAAAGAGTGCCGAAGTAGTGATCGAATGACCGATTCTCCTGCATCAACAAC
ACGATGTGCTCGATGTCGGTCAAATGTCCGGGGCAAGGCCCCGCTCCGTAGGCTTTTTCGATAATCGGAC
CAGCCAAGGACATGAAGGCCCCGGCGGTGGTAGCGGCGGCGGCTTTGGCAAAAAATTGTCGGCGGGTCA
Protein Sequence 
>gi|148662178|ref|YP_001283701.1| membrane-associated phospholipase C 2 [Mycobacterium tuberculosis H37Ra] MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: plcABC triple mutants are attenuated in mice (Raynaud et al., 2002).
COG COG3511M, under M: Cell wall/membrane/envelope biogenesis
References
Raynaud et al., 2002: Raynaud C, Guilhot C, Rauzier J, Bordat Y, Pelicic V, Manganelli R, Smith I, Gicquel B, Jackson M. Phospholipases C are involved in the virulence of Mycobacterium tuberculosis. Molecular microbiology. 2002; 45(1); 203-217. [PubMed: 12100560].