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plcC from Mycobacterium tuberculosis H37Ra

Victor ID 1858
Gene Name plcC from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5212285
NCBI Protein GI 148662177
Locus Tag MRA_2369
Protein Accession YP_001283700.1
Other Database IDs UniProtKB-ID: A5U538_MYCTA
UniRef100: UniRef100_A5WPW3
UniRef90: UniRef90_P95245
UniRef50: UniRef50_P95246
UniParc: UPI00001650EB
EMBL: CP000611
EMBL-CDS: ABQ74138.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000068731.
EnsemblGenome_TRS: EBMYCT00000068736
EnsemblGenome_PRO: EBMYCP00000066846
GenomeReviews: CP000611_GR
KEGG: mra:MRA_2369
eggNOG: COG3511
HOGENOM: HBG565180
OMA: FINAIME
ProtClustDB: CLSK791798
BioCyc: MTUB419947:MRA_2369-MONOMER
Taxonomy ID 419947
Gene Starting Position 2637075
Gene Ending Position 2638601
Gene Strand (Orientation) -
Protein Name phospholipase C 3 PlcC
DNA Sequence 
>gi|148659757:2637075-2638601 Mycobacterium tuberculosis H37Ra, complete genome
GCTAGCAGATGCCGCTGGGAATCGGCCGCGCGGGACCGGATTCCTGGACTGGCGTTGTTTGGGGGTAGGG
CACCCGATACGGCAGGCCTTCGTTCAAGAAACCCAGCACCACATTGGGCACGCACTTGGCGACCTTCGGC
AATTGACGGACCGGGTGGTCCAGATTGGGTGGCGACGGGTCCGGCGGGGCCGCGAAATTGAATGCCGACG
TCATATCGCCGGTGACACTGGCACGCCAGGGTGTCAAGTTGGGAACCGGCACCCCGAAACGCTTGCCGAT
CAATTGCAGCTGCGATGTGTGGTCGAACCGATCATGGACCATCAGCCCGCCGCGACTGTAAGGCGAAATG
ACGAAGCAGGGCACGCGAAAGCCCAAGCCGATGGGTCCACGTATTCCGCCGGAGCCGTCGACCTTGTCGA
TGTCAACACTGTTGGGAATCCATTCGCCGGGTGTGCCCTCCGGCGCGGTGAGCGGTGTGACGTGGTCGAA
GAAGCCGCCATGTTCGTCATAGGCGATGATCAACGCGGTTTTCTCCCACACCGCCGGATTGCGCAGCAAC
ACCCTTATCAAGTTCACGATCGTCACCGCACCGACTGCCACCGGGAATGACGGATGTTCGGACTCGACGG
TCAACGGAACGACCCAGGACACCTGGGGCAGCGTGTTGTTGATGACGTCGCGGATGAAATCCCACGGGTA
GGCCGGGGCGATGCCATAACGGGCCAGGTCCGACCTCGGATCTGCGGCCTGTTTGAAACTGCCCACATAC
CCGTTACGGCTCAAGGAAGTGTCGTTGAGCCCGCCGAGCAGCTTGCTGTTGTACACCTTCCAACTGATGC
CGGCGTCACTGAGGTTCTGCGGCATGATGCGCCAGGTGAAGGTCAACTTCGGCTGGATGGCGGGTTCGAC
GATCTGCGGCCCACCTTGATCCCCGTCGGGATTGACGGTGGCGCTGATCCAATAGAGCCGGTTAGGCATC
GTCCCGCCAAGAAGCGACGAGAAGTACTGGTCGCAGATCGTGAAGGTATCGGCCAACAAGTAGTGGATCG
GTATGTCAGGACGTGCGTAATAGCCCATCACCACGGGCGTGTTGGCCACCGACCGGGTCCGCGCCTGCGC
CGGCAGCCAGCCGTCATTGGCGCCGCCGTTCCATGACAAGTGCGCGGCAATCCACTGGTGGTCTGGGTCG
TTGACGCACTCGCCAACCCCGTTGGGACCCCCGGTGGTATTGATGCGGTAGGGCAGCGTAATGCCGGTGG
GGTCCAGCGCCTGCGTCTCCGGGTTCCAGCCCTTTTGTTGAAACAGCGGCGTCGGAGTGTCGAACCCGTC
GACGGCAGAAAGCGTGCCGAAATAGTGATCGAACGACCTGTTCTCCTGTAGGCACAGCACGATGTGCTCG
ATATCGGTCAAATGACCCGAGCAGGGACCGGCACCATAGGCCTTTTCGATCACCGGTGCGGCCCAGTCCG
TCAAAACCGCCGCTGCCCCGGCTCCAGCCGCCTTAGCCAGGAATGCTCGGCGTGACA
Protein Sequence 
>gi|148662177|ref|YP_001283700.1| phospholipase C 3 PlcC [Mycobacterium tuberculosis H37Ra] MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYFGTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNEGLPYRVPYPQTTPVQESGPARPIPSGIC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: plcABC triple mutants are attenuated in mice (Raynaud et al., 2002).
COG COG3511M, under M: Cell wall/membrane/envelope biogenesis
References
Raynaud et al., 2002: Raynaud C, Guilhot C, Rauzier J, Bordat Y, Pelicic V, Manganelli R, Smith I, Gicquel B, Jackson M. Phospholipases C are involved in the virulence of Mycobacterium tuberculosis. Molecular microbiology. 2002; 45(1); 203-217. [PubMed: 12100560].