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regX3 from Mycobacterium tuberculosis H37Ra

Victor ID 1857
Gene Name regX3 from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5212270
NCBI Protein GI 148660258
Locus Tag MRA_0498
Protein Accession YP_001281781.1
Other Database IDs UniProtKB-ID: A5TZL9_MYCTA
UniRef100: UniRef100_O07130
UniRef90: UniRef90_O07130
UniRef50: UniRef50_Q9F868
UniParc: UPI0000133841
EMBL: CP000611
EMBL-CDS: ABQ72219.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000065418.
EnsemblGenome_TRS: EBMYCT00000065423
EnsemblGenome_PRO: EBMYCP00000063533
GenomeReviews: CP000611_GR
KEGG: mra:MRA_0498
eggNOG: COG0745
HOGENOM: HBG753323
OMA: ITEFDRN
ProtClustDB: CLSK790554
BioCyc: MTUB419947:MRA_0498-MONOMER
Taxonomy ID 419947
Gene Starting Position 582118
Gene Ending Position 582801
Gene Strand (Orientation) +
Protein Name two component sensory transduction protein RegX3
DNA Sequence 
>gi|148659757:582118-582801 Mycobacterium tuberculosis H37Ra, complete genome
GATGACCAGTGTGTTGATTGTGGAGGACGAGGAGTCGCTGGCCGATCCGCTGGCGTTTCTGCTGCGCAAG
GAGGGCTTTGAGGCCACGGTGGTGACCGATGGTCCGGCAGCTCTCGCCGAGTTCGACCGGGCCGGCGCCG
ACATCGTCCTGCTCGATCTGATGCTGCCTGGGATGTCGGGTACCGATGTATGCAAGCAGTTGCGCGCTCG
GTCCAGCGTTCCGGTGATCATGGTGACCGCCCGGGATAGCGAGATCGACAAGGTGGTCGGCCTGGAGCTG
GGCGCTGACGACTACGTGACCAAGCCCTATTCGGCACGCGAGTTGATCGCACGCATCCGCGCGGTGCTGC
GCCGTGGCGGCGACGACGACTCGGAGATGAGCGATGGCGTGCTGGAGTCCGGGCCGGTTCGCATGGATGT
GGAGCGCCATGTCGTCTCGGTGAACGGTGACACCATCACGCTGCCGCTCAAGGAGTTCGACCTGCTGGAA
TACCTGATGCGCAACAGCGGGCGGGTGTTGACTCGCGGACAACTGATCGACCGGGTCTGGGGTGCGGACT
ACGTGGGCGACACCAAGACGCTCGACGTCCATGTCAAGCGGCTGCGCTCCAAGATCGAAGCCGACCCGGC
TAACCCGGTTCACTTGGTGACGGTGCGCGGGCTGGGCTACAAACTCGAGGGCTA
Protein Sequence 
>gi|148660258|ref|YP_001281781.1| two component sensory transduction protein RegX3 [Mycobacterium tuberculosis H37Ra] MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: senX3-regX3 deletion mutant is attenuated in mice (Parish et al., 2003).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Parish et al., 2003: Parish T, Smith DA, Roberts G, Betts J, Stoker NG. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, England). 2003; 149(Pt 6); 1423-1435. [PubMed: 12777483].