Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

senX3 from Mycobacterium tuberculosis H37Ra

Victor ID 1856
Gene Name senX3 from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5212269
NCBI Protein GI 148660257
Locus Tag MRA_0497
Protein Accession YP_001281780.1
Other Database IDs UniProtKB-ID: A5TZL8_MYCTA
UniRef100: UniRef100_P0A601
UniRef90: UniRef90_P0A601
UniRef50: UniRef50_A0QR01
UniParc: UPI000013589E
EMBL: CP000611
EMBL-CDS: ABQ72218.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000068011.
EnsemblGenome_TRS: EBMYCT00000068016
EnsemblGenome_PRO: EBMYCP00000066126
GenomeReviews: CP000611_GR
KEGG: mra:MRA_0497
eggNOG: COG0642
HOGENOM: HBG334875
OMA: MVTELIA
ProtClustDB: CLSK790553
BioCyc: MTUB419947:MRA_0497-MONOMER
Taxonomy ID 419947
Gene Starting Position 580658
Gene Ending Position 581890
Gene Strand (Orientation) +
Protein Name putative two component sensor histidine kinase SenX3
DNA Sequence 
>gi|148659757:580658-581890 Mycobacterium tuberculosis H37Ra, complete genome
TGTGACTGTGTTCTCGGCGCTGTTGCTGGCCGGGGTTTTGTCCGCGCTGGCACTGGCCGTCGGTGGTGCT
GTTGGAATGCGGCTGACGTCGCGGGTCGTCGAACAGCGCCAACGGGTGGCCACGGAGTGGTCGGGAATCA
CGGTTTCGCAGATGTTGCAATGCATTGTCACGCTGATGCCGCTGGGCGCCGCGGTGGTGGACACCCATCG
CGACGTTGTCTACCTCAACGAACGGGCCAAAGAGCTAGGTCTGGTGCGCGACCGCCAGCTCGATGATCAG
GCCTGGCGGGCCGCCCGGCAGGCGCTGGGTGGTGAAGACGTCGAGTTCGACCTGTCGCCGCGCAAGCGGT
CGGCCACGGGTCGATCCGGGCTATCAGTGCATGGGCATGCCCGGTTGCTGAGCGAGGAAGACCGCCGGTT
CGCCGTGGTGTTCGTGCACGACCAGTCGGATTATGCGCGGATGGAGGCGGCTAGGCGTGACTTCGTGGCC
AACGTCAGTCACGAGCTCAAGACGCCCGTCGGTGCCATGGCTCTACTCGCCGAGGCGCTGCTGGCGTCGG
CCGACGACTCCGAAACCGTTCGGCGGTTCGCCGAGAAGGTGCTCATTGAGGCCAACCGGCTCGGTGACAT
GGTCGCCGAGTTGATCGAGCTATCCCGGCTACAGGGCGCCGAGCGGCTACCCAATATGACCGACGTCGAC
GTCGATACGATTGTGTCGGAAGCGATTTCACGCCATAAGGTGGCGGCCGACAACGCCGACATCGAAGTCC
GCACCGACGCGCCCAGCAATCTGCGGGTGCTGGGCGACCAAACTCTGCTGGTTACCGCACTGGCAAACCT
GGTTTCCAATGCGATTGCCTATTCGCCGCGCGGGTCGCTGGTGTCGATCAGCCGTCGCCGTCGCGGTGCC
AACATCGAGATCGCCGTCACCGACCGGGGCATCGGCATCGCGCCGGAAGACCAGGAGCGGGTCTTCGAAC
GGTTCTTCCGGGGGGACAAGGCGCGCTCGCGTGCCACCGGAGGCAGCGGACTCGGGTTGGCCATCGTCAA
ACACGTCGCGGCTAATCACGACGGCACCATCCGCGTGTGGAGCAAACCGGGAACCGGGTCAACGTTCACC
TTGGCTCTTCCGGCGTTGATCGAGGCCTATCACGACGACGAGCGACCCGAGCAGGCGCGAGAGCCCGAAC
TGCGGTCAAACAGGTCACAACGAGAGGAAGAGCTGAGCCGATG
Protein Sequence 
>gi|148660257|ref|YP_001281780.1| two component sensor histidine kinase SenX3 [Mycobacterium tuberculosis H37Ra] MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: senX3-regX3 deletion mutant is attenuated in mice (Parish et al., 2003).
COG COG5002T, under T: Signal transduction mechanisms
References
Parish et al., 2003: Parish T, Smith DA, Roberts G, Betts J, Stoker NG. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, England). 2003; 149(Pt 6); 1423-1435. [PubMed: 12777483].