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sigL from Mycobacterium tuberculosis H37Ra

Victor ID 1854
Gene Name sigL from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5212242
NCBI Protein GI 148660510
Locus Tag MRA_0743
Protein Accession YP_001282033.1
Other Database IDs UniProtKB-ID: A5U0C1_MYCTA
UniRef100: UniRef100_A1KGL6
UniRef90: UniRef90_A1KGL6
UniRef50: UniRef50_A0QSI0
UniParc: UPI00000D10AF
EMBL: CP000611
EMBL-CDS: ABQ72471.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000068828.
EnsemblGenome_TRS: EBMYCT00000068833
EnsemblGenome_PRO: EBMYCP00000066943
GenomeReviews: CP000611_GR
KEGG: mra:MRA_0743
eggNOG: COG1595
HOGENOM: HBG753452
OMA: HSESTIT
ProtClustDB: PRK09645
BioCyc: MTUB419947:MRA_0743-MONOMER
Taxonomy ID 419947
Gene Starting Position 828848
Gene Ending Position 829381
Gene Strand (Orientation) +
Protein Name RNA polymerase sigma factor SigL
DNA Sequence 
>gi|148659757:828848-829381 Mycobacterium tuberculosis H37Ra, complete genome
CGTGGCTCGTGTGTCGGGCGCCGCGGCCGCTGAAGCCGCGTTGATGAGGGCGCTCTACGACGAGCATGCC
GCCGTGTTGTGGCGTTACGCGCTGCGCTTGACCGGGGATGCGGCCCAAGCCGAAGACGTCGTCCAAGAGA
CGCTGTTGCGGGCGTGGCAGCATCCGGAGGTGATCGGCGACACCGCGCGGCCGGCAAGGGCGTGGTTGTT
CACCGTCGCGCGCAACATGATCATCGACGAGCGGCGCAGCGCCCGGTTCCGCAATGTGGTCGGTTCGACC
GACCAATCGGGCACACCCGAGCAGTCGACGCCGGACGAGGTGAACGCCGCACTGGATCGGCTGCTGATCG
CCGATGCGCTGGCCCAACTGTCCGCCGAGCATAGGGCCGTGATCCAGCGGTCCTACTACCGCGGATGGTC
GACCGCACAGATTGCCACCGACCTCGGAATTGCCGAAGGAACGGTGAAGTCGCGATTGCACTACGCCGTG
CGCGCGTTGCGGCTCACTCTGCAGGAACTGGGAGTTACTCGATG
Protein Sequence 
>gi|148660510|ref|YP_001282033.1| RNA polymerase sigma factor SigL [Mycobacterium tuberculosis H37Ra] MARVSGAAAAEAALMRALYDEHAAVLWRYALRLTGDAAQAEDVVQETLLRAWQHPEVIGDTARPARAWLFTVARNMIIDERRSARFRNVVGSTDQSGTPEQSTPDEVNAALDRLLIADALAQLSAEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRALRLTLQELGVTR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sigL mutant is attenuated in mice (Hahn et al., 2005).
COG COG1595K, under K: Transcription
References
Hahn et al., 2005: Hahn MY, Raman S, Anaya M, Husson RN. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. Journal of bacteriology. 2005; 187(20); 7062-7071. [PubMed: 16199577].