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mce3A from Mycobacterium tuberculosis H37Ra

Victor ID 1852
Gene Name mce3A from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5211946
NCBI Protein GI 148661775
Locus Tag MRA_1977
Protein Accession YP_001283298.1
Other Database IDs UniProtKB-ID: A5U3Y6_MYCTA
UniRef100: UniRef100_A5U3Y6
UniRef90: UniRef90_A5U3Y6
UniRef50: UniRef50_A4T971
UniParc: UPI000004B718
EMBL: CP000611
EMBL-CDS: ABQ73736.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000067206.
EnsemblGenome_TRS: EBMYCT00000067211
EnsemblGenome_PRO: EBMYCP00000065321
GenomeReviews: CP000611_GR
KEGG: mra:MRA_1977
eggNOG: COG1463
HOGENOM: HBG659494
OMA: DTGWGTG
ProtClustDB: CLSK799855
BioCyc: MTUB419947:MRA_1977-MONOMER
Taxonomy ID 419947
Gene Starting Position 2219226
Gene Ending Position 2220503
Gene Strand (Orientation) +
Protein Name MCE-family protein Mce3A
DNA Sequence 
>gi|148659757:2219226-2220503 Mycobacterium tuberculosis H37Ra, complete genome
CATGAGACGCGGGCCGGGTCGACACCGTTTGCACGACGCGTGGTGGACGCTGATCCTGTTCGCGGTGATC
GGGGTGGCTGTCCTGGTGACGGCGGTGTCCTTCACGGGCAGCTTGCGGTCGACTGTGCCGGTGACGCTGG
CGGCCGACCGCTCCGGGCTGGTGATGGACTCCGGCGCCAAGGTCATGATGCGCGGTGTGCAGGTCGGCCG
GGTCGCCCAGATCGGTCGGATCGAGTGGGCCCAGAACGGGGCGAGCCTCAGACTGGAGATCGACCCCGAC
CAGATCCGGTACATCCCGGCCAATGTCGAGGCACAGATCAGCGCCACCACCGCATTCGGTGCCAAGTTCG
TCGACCTGGTGATGCCGCAAAACCCAAGTCGTGCACGGCTGTCCGCTGGGGCGGTACTGCATTCGAAGAA
CGTCAGCACGGAAATCAACACCGTCTTCGAAAACGTCGTCGACCTGCTCAACATGATCGACCCGCTGAAA
CTGAACGCCGTGCTGACCGCGGTCGCCGACGCCGTTCGCGGGCAAGGTGAACGGATAGGCCAGGCCACCA
CCGACCTCAACGAGGTGCTGGAGGCACTCAACGCACGCGGCGACACCATCGGCGGCAACTGGCGATCGCT
CAAGAACTTCACCGACACCTATGACGCGGCCGCCCAAGACATCCTGACGATCCTGAACGCCGCCAGCACC
ACCAGTGCGACCGTCGTGAATCATTCGACGCAGCTGGATGCCTTGCTACTCAACGCCATCGGACTATCCA
ACGCTGGCACCAACCTGCTTGGCAGCAGCCGAGACAATCTCGTCGGCGCGGCCGACATCCTGGCGCCGAC
CACGAGCCTGCTGTTCAAGTACAACCCCGAATACACCTGCTTCCTGCAGGGCGCCAAGTGGTATCTCGAC
AACGGCGGCTATGCGGCCTGGGGCGGGGCCGACGGGCGCACGCTACAACTCGATGTGGCGCTACTGTTCG
GCAACGACCCCTATGTCTATCCGGACAACCTGCCGGTTGTCGCGGCCAAGGGGGGTCCCGGCGGAAGGCC
GGGATGCGGGCCATTGCCGGATGCCACCCACAACTTCCCGGTGCGCCAGCTGGTCACCAACACCGGATGG
GGAACCGGGCTGGACATCCGGCCCAACCCCGGCATCGGGCATCCCTGCTGGGCCAACTACTTCCCGGTGA
CCCGCGCGGTGCCCGAGCCGCCGTCGATCCGTCAGTGCATCCCCGGGCCGGCGATCGGGCCCAACCCCGC
GGCGGGGGAGCAGCCATG
Protein Sequence 
>gi|148661775|ref|YP_001283298.1| MCE-family protein Mce3A [Mycobacterium tuberculosis H37Ra] MRRGPGRHRLHDAWWTLILFAVIGVAVLVTAVSFTGSLRSTVPVTLAADRSGLVMDSGAKVMMRGVQVGRVAQIGRIEWAQNGASLRLEIDPDQIRYIPANVEAQISATTAFGAKFVDLVMPQNPSRARLSAGAVLHSKNVSTEINTVFENVVDLLNMIDPLKLNAVLTAVADAVRGQGERIGQATTDLNEVLEALNARGDTIGGNWRSLKNFTDTYDAAAQDILTILNAASTTSATVVNHSTQLDALLLNAIGLSNAGTNLLGSSRDNLVGAADILAPTTSLLFKYNPEYTCFLQGAKWYLDNGGYAAWGGADGRTLQLDVALLFGNDPYVYPDNLPVVAAKGGPGGRPGCGPLPDATHNFPVRQLVTNTGWGTGLDIRPNPGIGHPCWANYFPVTRAVPEPPSIRQCIPGPAIGPNPAAGEQP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mce3A mutant is attenuated in mice (Gioffré et al., 2005).
COG COG1463Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Gioffré et al., 2005: Gioffré A, Infante E, Aguilar D, Santangelo MP, Klepp L, Amadio A, Meikle V, Etchechoury I, Romano MI, Cataldi A, Hernández RP, Bigi F. Mutation in mce operons attenuates Mycobacterium tuberculosis virulence. Microbes and infection / Institut Pasteur. 2005; 7(3); 325-334. [PubMed: 15804490].