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hbhA from Mycobacterium tuberculosis H37Ra

Victor ID 1850
Gene Name hbhA from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5211814
NCBI Protein GI 148660242
Locus Tag MRA_0482
Protein Accession YP_001281765.1
Other Database IDs UniProtKB-ID: HBHA_MYCTA
UniRef100: UniRef100_A1KFU9
UniRef90: UniRef90_A1KFU9
UniRef50: UniRef50_A1KFU9
UniParc: UPI000016522A
EMBL: CP000611
EMBL-CDS: ABQ72203.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000065972
EnsemblGenome_TRS: EBMYCT00000065977
EnsemblGenome_PRO: EBMYCP00000064087
GenomeReviews: CP000611_GR
KEGG: mra:MRA_0482
eggNOG: NOG11132
HOGENOM: HBG569842
OMA: VGEQAAK
ProtClustDB: CLSK790542
BioCyc: MTUB419947:MRA_0482-MONOMER
Taxonomy ID 419947
Gene Starting Position 567106
Gene Ending Position 567705
Gene Strand (Orientation) +
Protein Name iron-regulated heparin binding hemagglutinin Hbha
DNA Sequence 
>gi|148659757:567106-567705 Mycobacterium tuberculosis H37Ra, complete genome
CATGGCTGAAAACTCGAACATTGATGACATCAAGGCTCCGTTGCTTGCCGCGCTTGGAGCGGCCGACCTG
GCCTTGGCCACTGTCAACGAGTTGATCACGAACCTGCGTGAGCGTGCGGAGGAGACTCGTACGGACACCC
GCAGCCGGGTCGAGGAGAGCCGTGCTCGCCTGACCAAGCTGCAGGAAGATCTGCCCGAGCAGCTCACCGA
GCTGCGTGAGAAGTTCACCGCCGAGGAGCTGCGTAAGGCCGCCGAGGGCTACCTCGAGGCCGCGACTAGC
CGGTACAACGAGCTGGTCGAGCGCGGTGAGGCCGCTCTAGAGCGGCTGCGCAGCCAGCAGAGCTTCGAGG
AAGTGTCGGCGCGCGCCGAAGGCTACGTGGACCAGGCGGTGGAGTTGACCCAGGAGGCGTTGGGTACGGT
CGCATCGCAGACCCGCGCGGTCGGTGAGCGTGCCGCCAAGCTGGTCGGCATCGAGCTGCCTAAGAAGGCT
GCTCCGGCCAAGAAGGCCGCTCCGGCCAAGAAGGCCGCTCCGGCCAAGAAGGCGGCGGCCAAGAAGGCGC
CCGCGAAGAAGGCGGCGGCCAAGAAGGTCACCCAGAAGTA
Protein Sequence 
>gi|148660242|ref|YP_001281765.1| iron-regulated heparin binding hemagglutinin Hbha [Mycobacterium tuberculosis H37Ra] MAENSNIDDIKAPLLAALGAADLALATVNELITNLRERAEETRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELRKAAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLVGIELPKKAAPAKKAAPAKKAAPAKKAAAKKAPAKKAAAKKVTQK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hbhA mutant is attenuated in attachment and invasion of pneumocytes (Pethe et al., 2001).
References
Pethe et al., 2001: Pethe K, Alonso S, Biet F, Delogu G, Brennan MJ, Locht C, Menozzi FD. The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination. Nature. 2001; 412(6843); 190-194. [PubMed: 11449276].