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thiE

Victor ID 185
Gene Name thiE
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886391
NCBI Protein GI 15607555
Locus Tag Rv0414c
Protein Accession NP_214928.1
Other Database IDs UniProtKB-ID: THIE_MYCTU
UniRef100: UniRef100_A1KFN6
UniRef90: UniRef90_A1KFN6
UniRef50: UniRef50_A0JYP1
UniParc: UPI0000136DD9
EMBL: BX842573
EMBL: AE000516
EMBL-CDS: CAB06584.1
EMBL-CDS: AAK44651.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000001412
EnsemblGenome_TRS: EBMYCT00000001412
EnsemblGenome_PRO: EBMYCP00000001412
EnsemblGenome: EBMYCG00000070675
EnsemblGenome_TRS: EBMYCT00000070680
EnsemblGenome_PRO: EBMYCP00000068739
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 500349
Gene Ending Position 501017
Gene Strand (Orientation) -
Protein Name thiamine-phosphate pyrophosphorylase
DNA Sequence 
>gi|57116681:500349-501017 Mycobacterium tuberculosis H37Rv, complete genome
ATCAGTTCGCTGCTGTAAGCGCCGACCGGAGCTGCTCGGCCGCCGCACGTGGGTCGTCAGCCGAGGTGAT
CGCCCGCACCACCACGATCCGGCGAGCGCCGGCATCGAGCACGGCCGGCAGCCGTTGCGCGTTGATGCCG
CCGATAGCGAACCACGGCTTGTCGTCGCCGCCGAGTTCGGCGGCGACCCGTACCAGCCCCAGACCCGGCG
CCGCACGGCCAGGCTTGGTCGGTGTCGGCCAACATGGTCCGACACAGAAATAGTCGGCGTCGCCGGCGGC
GGCCGCAGCAACCTGGTCGGGGTCGTGGGTGGACCGGCCGATGAGGGTATCCGGTGCCAGGATCTGTCGT
GCGACGTTCACGGGCAGGTCGCGTTGACCCAGATGCAGCACGTCGGCGCCGGCCGCGCGGGCAATATCGG
CGCGGTCGTTGACCGCGAATAGGGCGCCGTACCGGTGCGCTGCGTCGGCCAGGATCTCGCAGGCGGCCAG
TTCGTCACGCGCCTGTAGCGGGCCGAACCGCAGCTCACCGGGTGAGCCCTTGTCGCGCAACTGGATGATG
TCCACTCCGCCGGCCAGGGCGGCCTCGGCGAACTGAGCCAAGTCGCCGCGTTCCCGACGGGCGTCGGTGC
ACAGATACAGCCTTGCCGATGCCAGACGGGATTCGTGCA
Protein Sequence 
>gi|15607555|ref|NP_214928.1| thiamine-phosphate synthase [Mycobacterium tuberculosis H37Rv] MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0352H, under H: Coenzyme transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].