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mce2A from Mycobacterium tuberculosis H37Ra

Victor ID 1849
Gene Name mce2A from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5211750
NCBI Protein GI 148660358
Locus Tag MRA_0596
Protein Accession YP_001281881.1
Other Database IDs UniProtKB-ID: A5TZW9_MYCTA
UniRef100: UniRef100_A5TZW9
UniRef90: UniRef90_A5WJV4
UniRef50: UniRef50_A5TYP4
UniParc: UPI00000CCB3D
EMBL: CP000611
EMBL-CDS: ABQ72319.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000068367.
EnsemblGenome_TRS: EBMYCT00000068372
EnsemblGenome_PRO: EBMYCP00000066482
GenomeReviews: CP000611_GR
KEGG: mra:MRA_0596
eggNOG: COG1463
HOGENOM: HBG659494
OMA: AVAYTKA
ProtClustDB: CLSK799409
BioCyc: MTUB419947:MRA_0596-MONOMER
Taxonomy ID 419947
Gene Starting Position 688130
Gene Ending Position 689344
Gene Strand (Orientation) +
Protein Name MCE-family protein Mce2A
DNA Sequence 
>gi|148659757:688130-689344 Mycobacterium tuberculosis H37Ra, complete genome
GGTGCCAACGCTGGTGACGAGGAAGAACCGACGTGCGTGGCTGTATGTGGAGGGTGTTGTCCTGCTGTTG
GTGGGCGCGTTGGTGCTCGTATTGGTGTACAAGCAGTTTCGTGGGGAATTCACGCCGAAGACCGAGCTGA
CTATGGTCGCCTTCCGGGCTGGGCTGGTTATGGAAGCTGGATCCAAAGTCACCTACAACGGGGTGGAGAT
CGGCCGGGTGGGCAGCATTTCGGAGATTGAGCGTGACGGCCGGCCGGCGGCGAAGCTGGTTTTGGACGTG
AATCCTCGCTACATCAGCCTGATTCCGGTCAATGTGGTGGCCGATATCGAGGCGGCCACCCTGTTCGGCA
ACAAGTATGTTGCGCTGTCCGCGCCGAAAATTCCTCAACAGCAGCGGATTTCCTCACATGACGTGATTGA
TGTGGGGTCGGTGACCACCGAATTCAACACGTTGTTCGAGACGATCACCTCGATCGCCGAGAAGGTGGAT
CCGATCGAGCTGAACGCGACGCTGTCCGCGGTAGCACAGGCGCTGGATGGGCTGGGCGGCAAGTTCGGTG
AGTCGATCGTTAATGGCAATCAGATTCTGGCGCAATTAAATCCGCGGCTGCCGCAGCTCGGCTATGATGT
TCGGCGGTTGGCGGATCTCGGTGAGGTCTATGTCGATGCTTCGCCGGATCTGTGGTCCTTTCTGCAGAAC
GCACTGACCACTGCGCGCACATTGACCAGCCAACAGCGCGATCTGGATGCCGCGTTGTTGGCGGCTACGG
GTGCGGGCAACACCGGTGAAGACGTTTTTGCTCGAGGCGGGCCGTATCTTGCGCGCGCAGCCGCCGATCT
GGTGCCCACCGCTACGCTGCTGGACACCTACAGTCCCGAACTGTTCTGCATGATCCGCAACTTTCACGAC
GCTGCGCCCAAAGTCGCGGACGCGGTGGGCGGCAACGGCTATTCGCTAGCGGCCGCCGGAACGATTTTGG
GAGCACCCAATCCCTATGTCTATCCGGACAATCTGCCGCGGGTGAATGCCCACGGTGGACCCGGGGGCCG
ACCGGGCTGCTGGCAGACGATCACCCGGGAGCTGTGGCCGGCACCCTATCTGGTGATGGACACCGGTGCC
AGCCTCGCACCGTACAACCACGTCGAGCTCGGCCAACCGATGTTCACTGAATACGTATGGGGACGCCAAT
ACGGAGAGAACACGATCAACCCATG
Protein Sequence 
>gi|148660358|ref|YP_001281881.1| MCE-family protein Mce2A [Mycobacterium tuberculosis H37Ra] MPTLVTRKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTPKTELTMVAFRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNPRYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVTTEFNTLFETITSIAEKVDPIELNATLSAVAQALDGLGGKFGESIVNGNQILAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQRDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELFCMIRNFHDAAPKVADAVGGNGYSLAAAGTILGAPNPYVYPDNLPRVNAHGGPGGRPGCWQTITRELWPAPYLVMDTGASLAPYNHVELGQPMFTEYVWGRQYGENTINP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mce2A mutant is attenuated in mice (Gioffré et al., 2005).
COG COG1463Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Gioffré et al., 2005: Gioffré A, Infante E, Aguilar D, Santangelo MP, Klepp L, Amadio A, Meikle V, Etchechoury I, Romano MI, Cataldi A, Hernández RP, Bigi F. Mutation in mce operons attenuates Mycobacterium tuberculosis virulence. Microbes and infection / Institut Pasteur. 2005; 7(3); 325-334. [PubMed: 15804490].