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sigD from Mycobacterium tuberculosis H37Ra

Victor ID 1847
Gene Name sigD from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5211733
NCBI Protein GI 148663278
Locus Tag MRA_3454
Protein Accession YP_001284801.1
Other Database IDs UniProtKB-ID: A5U889_MYCTA
UniRef100: UniRef100_P66812
UniRef90: UniRef90_P66812
UniRef50: UniRef50_P66812
UniParc: UPI0000134831
EMBL: CP000611
EMBL-CDS: ABQ75239.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000067162.
EnsemblGenome_TRS: EBMYCT00000067167
EnsemblGenome_PRO: EBMYCP00000065277
GenomeReviews: CP000611_GR
KEGG: mra:MRA_3454
eggNOG: COG1595
HOGENOM: HBG753452
OMA: ICLAVAT
ProtClustDB: PRK09648
BioCyc: MTUB419947:MRA_3454-MONOMER
Taxonomy ID 419947
Gene Starting Position 3841715
Gene Ending Position 3842353
Gene Strand (Orientation) -
Protein Name RNA polymerase sigma factor SigD
DNA Sequence 
>gi|148659757:3841715-3842353 Mycobacterium tuberculosis H37Ra, complete genome
TTCACGCATAGTCACCTGCCGCAACAATCTCGTCCTTCAGCCGCTGAAGTGCACGGTGTTGGGCCACCCG
GACCGCCCCCGTGGTGCTGCCGACGGCGGCGGCGGTCTCTTCCGCGGACAGGCCGACGACAACACGCAGA
ATGAGGATCTCGCGTTGCTTGGCCGGCAAGATCTCAAGCAATTCGTTCATCCGGGTGACCGAATCGGCCT
CGATGGCCATCTGCTCCGGGCCGGCGTCGGCTGACCAGCGCTCAGGAAGCGTTTCGGCGGGATAGGCCCG
GTCACGGCCGGCTGCCCGATGGGCGTCGGCAACCTTGTGCGCCGCGATGCCGTACAGAAACGCCAGGAAT
GGCCGGCCGCGGTCCCGATAGCGCGGCAGCGCCGTTATGGTGGCCAAGCACACCTCCTGTGCCACGTCAT
CTGCTGACAGGCCGCTCCGCTCGACCGTGCCGACTCGCGCTCGGCAATATCGCACGACGATCGGGCGGAT
GGTCTCCAGCACCTCCCGAAGCGCGTTCCGGTCTCCTGCCACGGCCTCCGCAACCACAGCGTCGAGACGT
TCCCCTTGCATTGTCATCGACGGCGATATCTCCAACGTTACGAAGCGGACACATCCCGGGCTAACTCCCG
GATCGACCA
Protein Sequence 
>gi|148663278|ref|YP_001284801.1| RNA polymerase sigma factor SigD [Mycobacterium tuberculosis H37Ra] MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCRARVGTVERSGLSADDVAQEVCLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRDRAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPAKQREILILRVVVGLSAEETAAAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sigD mutant is attenuated in human macrophages and mice (Calamita et al., 2005).
COG COG1595K, under K: Transcription
References
Calamita et al., 2005: Calamita H, Ko C, Tyagi S, Yoshimatsu T, Morrison NE, Bishai WR. The Mycobacterium tuberculosis SigD sigma factor controls the expression of ribosome-associated gene products in stationary phase and is required for full virulence. Cellular microbiology. 2005; 7(2); 233-244. [PubMed: 15659067].