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hspR from Mycobacterium tuberculosis H37Ra

Victor ID 1846
Gene Name hspR from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5211729
NCBI Protein GI 148660119
Locus Tag MRA_0362
Protein Accession YP_001281642.1
Other Database IDs UniProtKB-ID: A5TZ80_MYCTA
UniRef100: UniRef100_A5TZ80
UniRef90: UniRef90_A5TZ80
UniRef50: UniRef50_A0LWT0
UniParc: UPI00000D0FD9
EMBL: CP000611
EMBL-CDS: ABQ72080.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000068620.
EnsemblGenome_TRS: EBMYCT00000068625
EnsemblGenome_PRO: EBMYCP00000066735
GenomeReviews: CP000611_GR
KEGG: mra:MRA_0362
eggNOG: COG0789
HOGENOM: HBG710951
OMA: ISVVAKI
ProtClustDB: CLSK790457
BioCyc: MTUB419947:MRA_0362-MONOMER
Taxonomy ID 419947
Gene Starting Position 425000
Gene Ending Position 425380
Gene Strand (Orientation) +
Protein Name heat shock protein transcriptional repressor HspR
DNA Sequence 
>gi|148659757:425000-425380 Mycobacterium tuberculosis H37Ra, complete genome
GATGGCGAAGAACCCAAAGGACGGGGAATCCCGGACGTTTTTGATCTCGGTAGCCGCCGAGCTAGCCGGC
ATGCATGCACAGACCCTGCGTACCTACGATCGTCTTGGGTTGGTCAGCCCGCGGCGCACCTCCGGTGGCG
GGCGCCGCTATTCCCTGCATGACGTCGAGTTGCTGCGCCAGGTGCAGCACCTCTCGCAGGACGAGGGGGT
CAACTTGGCCGGCATCAAGCGCATTATTGAACTGACCAGTCAGGTCGAGGCGCTGCAGTCCAGGTTGCAA
GAGATGGCTGAGGAGTTGGCGGTGTTGCGTGCCAACCAGCGCCGCGAGGTCGCGGTGGTGCCGAAGAGCA
CCGCCCTGGTCGTCTGGAAACCGCGCCGGTG
Protein Sequence 
>gi|148660119|ref|YP_001281642.1| heat shock protein transcriptional repressor HspR [Mycobacterium tuberculosis H37Ra] MAKNPKDGESRTFLISVAAELAGMHAQTLRTYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIELTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWKPRR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hspR mutant is attenuated in mice (Stewart et al., 2001).
COG COG0789K, under K: Transcription
References
Stewart et al., 2001: Stewart GR, Snewin VA, Walzl G, Hussell T, Tormay P, O'Gaora P, Goyal M, Betts J, Brown IN, Young DB. Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection. Nature medicine. 2001; 7(6); 732-737. [PubMed: 11385512].