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xthA from Mycobacterium tuberculosis H37Rv

Victor ID 184
Gene Name xthA from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886370
NCBI Protein GI 15607568
Locus Tag Rv0427c
Protein Accession NP_214941.1
Other Database IDs UniProtKB-ID: P96273_MYCTU
UniRef100: UniRef100_A5TZF3
UniRef90: UniRef90_A5TZF3
UniRef50: UniRef50_A0JS00
UniParc: UPI00000D5F1F
EMBL: AE000516
EMBL: BX842573
EMBL-CDS: AAK44665.1
EMBL-CDS: CAB06567.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
HSSP: P27695
EnsemblGenome: EBMYCG00000001502.
EnsemblGenome_TRS: EBMYCT00000001502
EnsemblGenome_PRO: EBMYCP00000001502
EnsemblGenome: EBMYCG00000072358.
EnsemblGenome_TRS: EBMYCT00000072363
EnsemblGenome_PRO: EBMYCP00000070422
GenomeReviews: AE000516
Taxonomy ID 83332
Gene Starting Position 516016
Gene Ending Position 516891
Gene Strand (Orientation) -
Protein Name PROBABLE EXODEOXYRIBONUCLEASE III PROTEIN XTHA (EXONUCLEASE III) (EXO III) (AP ENDONUCLEASE VI)
DNA Sequence 
>gi|57116681:516016-516891 Mycobacterium tuberculosis H37Rv, complete genome
CCTACCCGGCGTGCAGGTCGACGAGCACCGGAGCGTGGTCGCTGGGCGCTTTGCCTTTACGCTCCTCGCG
TACGATCTGGGCGTCCATCACCCGGGCGGCCAACGCCGGCGAGCCGAGGATGAAGTCGATGCGCATGCCC
TGTTTCTTCGGGAACCGCAGCTGCGTGTAATCCCAGTAGGTGTAAACCCCGGGTCCCGGGGTGAAAGGCC
GTACTACATCGGTGAATTGCGCGTCGACAATGGCGTTGAACGCCTTGCGCTCGGGTTCGGAAACGTGCGT
GCAGCCGGCGAAGAATTCGGTGCTCCAGACATCATCATCGGTCGGAGCGATGTTCCAGTCGCCCATCAGT
GCGATTGGTGCGGCGGGATCGTCACGTAGCCAGCCTTCGGCCGTATCACGCAGCGCGGCAAGCCAATCCA
ACTTGTAGGTGTAGTGCGGATCGTCCAGGGCGCGCCCGTTGGGCACGTAGAGGCTCCACACCCGGATGCC
GCCGCAGGTGGCGCCCAGGGCACGGGCCTCCGTCGTGGCGGCCACTTCCGGCTTGCCGCTCCAGCTGGGC
TGGCCGTCGAACCCAACCCGCACGTCGTCGAGGCCGACGCGGGATGCGATCGCCACGCCGTTCCACTGAT
CGAAGCCGACGTGTGCGACGTCATAGCCGAGTTCGAACAGCGGCAAGGCCGGGAATTGGCCGTCCGGGCA
CTTGGTCTCCTGCATGGCCAACACGTCGACATCGGCGCGCCCAAGCCAATCGAGGACACGATCCAACCGG
GTGCGAATCGAATTCACATTCCAGGTGGCCAGCCGCAGCAGCGGCGATCGCAAGCGCGGCGAAGCCGGGC
GTTGGGGGTGGCCGCCGTCAATTGTGCCGTCGGGCA
Protein Sequence 
>gi|15607568|ref|NP_214941.1| exodeoxyribonuclease III protein XthA [Mycobacterium tuberculosis H37Rv] MPDGTIDGGHPQRPASPRLRSPLLRLATWNVNSIRTRLDRVLDWLGRADVDVLAMQETKCPDGQFPALPLFELGYDVAHVGFDQWNGVAIASRVGLDDVRVGFDGQPSWSGKPEVAATTEARALGATCGGIRVWSLYVPNGRALDDPHYTYKLDWLAALRDTAEGWLRDDPAAPIALMGDWNIAPTDDDVWSTEFFAGCTHVSEPERKAFNAIVDAQFTDVVRPFTPGPGVYTYWDYTQLRFPKKQGMRIDFILGSPALAARVMDAQIVREERKGKAPSDHAPVLVDLHAG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0708L, under L: Replication, recombination and repair
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].