Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

purH from Yersinia pestis Pestoides F

Victor ID 1823
Gene Name purH from Yersinia pestis Pestoides F
Sequence Strain (Species/Organism) Yersinia pestis Pestoides F
NCBI Gene ID 5063065
NCBI Protein GI 145600973
Locus Tag YPDSF_3726
Protein Accession YP_001165049.1
Other Database IDs UniProtKB-ID: PUR9_YERPP
UniRef100: UniRef100_A7FNG6
UniRef90: UniRef90_A1JIJ7
UniRef50: UniRef50_A9IZD0
UniParc: UPI00000CDA75
EMBL: CP000668
EMBL-CDS: ABP42076.1
RefSeq_NT: NC_009381.1
GenomeReviews: CP000668_GR
KEGG: ypp:YPDSF_3726
eggNOG: COG0138
HOGENOM: HBG498048
OMA: ASDGFFP
ProtClustDB: PRK00881
BioCyc: YPES386656:YPDSF_3726-MONOMER
Taxonomy ID 386656
Gene Starting Position 4285639
Gene Ending Position 4287228
Gene Strand (Orientation) +
Protein Name bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
DNA Sequence 
>gi|145597324:4285639-4287228 Yersinia pestis Pestoides F, complete genome
CATGCAACAACGCCGTCCAATCCGCCGTGCTCTACTCAGTGTGTCTGACAAAGCAGGTATCATCGAATTC
GCCCAAGCACTTTCTCAACGCGGTATCGAGTTACTTTCCACCGGTGGGACTGCCCGCCTGCTGGCTGATG
CTGGTTTACCCGTTACCGAAGTGTCTGACTACACCGGTTTCCCGGAAATGATGGATGGACGTGTGAAGAC
TTTGCATCCAAAGGTGCATGGTGGGATTTTAGGTCGTCGTGGTCAGGATGATGGCATCATGGCTCAACAT
GGCATTCAGCCCATTGATATTGTCGTCGTTAATTTATATCCCTTCGCCCAGACGGTTGCCCGCCCGGATT
GCTCGTTGGAAGATGCGGTTGAGAATATTGATATTGGTGGCCCAACCATGGTTCGCTCTGCGGCCAAGAA
CCATAAAGATGTCGCCATCGTGGTGAAGAGTAGCGACTACCCCGCCATTATTACTGAGCTTGATAATAAT
GATGGTTCGTTGACTTACCCCACCCGCTTCAATCTGGCCATTAAAGCTTTCGAACACACCGCCGCCTACG
ACAGCATGATCGCCAACTACTTCGGCACACTGGTGCCACCTTATCATGGTGATACGGAACAGCCTTCCGG
CCACTTCCCTCGCACCCTAAATCTTAACTATATAAAGAAGCAGGATATGCGTTACGGTGAAAACAGCCAC
CAGCAAGCTGCCTTCTATATAGAAGAAGATGTCAAAGAGGCATCCGTTGCCACTGCCCAGCAATTACAAG
GGAAAGCCCTCTCTTATAACAATATTGCGGATACCGATGCCGCGCTGGAATGCGTGAAAGAGTTCAGTGA
ACCAGCCTGTGTGATCGTTAAACATGCCAACCCATGCGGTGTGGCTATCGGTGATTCTATTCTTGCCGCT
TATGAACGTGCCTATCAAACCGATCCAACCTCAGCTTTCGGTGGCATCATCGCCTTTAACCGTGAATTGG
ATGCAGCAACGGCCAGCGCGATCATCAGCCGCCAGTTTGTCGAAGTGATCATTGCGCCAACAGTCAGCTC
TGATGCATTGGCATTGCTTGCAGCTAAACAAAATGTCCGAGTCCTGACTTGTGGCCAGTGGCAAGCACGT
TCAGCAGGTTTAGATTTCAAACGTGTTAATGGGGGTTTGCTGGTACAAGAACGCGATTTAGGTATGGTGA
CGGCGGCCGACCTTCGCGTGGTTTCCAAGCGTCAGCCTACCGAACAGGAACTGCGTGATGCGCTGTTCTG
CTGGAAAGTGGCTAAGTTTGTTAAATCCAATGCGATTGTCTATGCCCGCGATAACATGACAATCGGTATA
GGTGCCGGCCAAATGAGCCGCGTGTACTCTGCGAAAATAGCCGGTATCAAGGCCGCAGATGAAGGGCTGG
AAGTGGCTGGCTCAGCCATGGCCTCTGATGCCTTCTTCCCGTTCCGTGATGGTATTGATGCCGCCGCGGC
TGTGGGCATTACTTGTGTCATCCAACCGGGCGGCTCAATTCGTGATGATGAAGTCATCGCGGCTGCTGAT
GAACACAGTATTGCCATGATCTTCACCGACATGCGCCATTTCCGTCATTA
Protein Sequence 
>gi|145600973|ref|YP_001165049.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Yersinia pestis Pestoides F] MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHSIAMIFTDMRHFRH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purH mutant is attenuated in mice (Flashner et al., 2004).
COG COG0138F, under F: Nucleotide transport and metabolism
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].