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sodC from Mycobacterium tuberculosis H37Rv

Victor ID 182
Gene Name sodC from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886358
NCBI Protein GI 15607573
Locus Tag Rv0432
Protein Accession NP_214946.1
Other Database IDs UniProtKB-ID: SODC_MYCTU
UniRef100: UniRef100_P0A609
UniRef90: UniRef90_P0A609
UniRef50: UniRef50_P0A609
UniParc: UPI0000135BB1
EMBL: BX842573
EMBL: AE000516
EMBL-CDS: CAB06572.1
EMBL-CDS: AAK44670.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 1PZS
EnsemblGenome: EBMYCG00000003368
EnsemblGenome_TRS: EBMYCT00000003370
EnsemblGenome_PRO: EBMYCP00000003370
EnsemblGenome: EBMYCG00000071956
EnsemblGenome_TRS: EBMYCT00000071961
EnsemblGenome_PRO: EBMYCP00000070020
GenomeReviews: AE000516_GR
Gen
Taxonomy ID 83332
Gene Starting Position 519599
Gene Ending Position 520321
Gene Strand (Orientation) +
Protein Name PROBABLE PERIPLASMIC SUPEROXIDE DISMUTASE [CU-ZN] SODC
DNA Sequence 
>gi|57116681:519599-520321 Mycobacterium tuberculosis H37Rv, complete genome
TATGCCAAAGCCCGCCGATCACCGCAATCACGCAGCTGTCAGCACGTCGGTCCTGTCCGCGTTGTTTCTG
GGCGCCGGTGCCGCGCTGCTGAGCGCATGCTCGTCGCCGCAGCACGCGTCTACAGTTCCGGGTACCACGC
CGTCGATTTGGACCGGATCGCCCGCGCCGTCGGGACTTTCGGGTCACGACGAGGAGTCGCCCGGTGCGCA
GAGCCTGACCAGTACCCTGACGGCGCCCGACGGCACGAAGGTAGCGACCGCGAAGTTCGAGTTCGCCAAC
GGCTATGCCACCGTCACGATCGCGACGACCGGCGTCGGTAAGCTCACGCCCGGCTTCCACGGCCTACACA
TCCACCAGGTGGGTAAGTGTGAGCCCAACTCGGTTGCCCCCACCGGCGGTGCGCCCGGCAACTTTCTGTC
CGCCGGCGGCCACTACCACGTGCCAGGGCATACCGGCACCCCCGCCAGCGGCGACCTGGCCTCGCTGCAG
GTACGCGGTGACGGTTCGGCGATGCTGGTGACCACCACCGACGCCTTCACCATGGACGACCTGCTGAGCG
GCGCGAAAACCGCGATCATCATTCACGCCGGCGCCGACAACTTTGCCAACATTCCGCCAGAACGCTACGT
CCAGGTCAATGGGACTCCGGGTCCCGACGAGACGACGTTGACCACCGGCGACGCCGGCAAGCGGGTGGCG
TGCGGTGTCATTGGTTCCGGCTA
Protein Sequence 
>gi|15607573|ref|NP_214946.1| superoxide dismutase [Mycobacterium tuberculosis H37Rv] MPKPADHRNHAAVSTSVLSALFLGAGAALLSACSSPQHASTVPGTTPSIWTGSPAPSGLSGHDEESPGAQSLTSTLTAPDGTKVATAKFEFANGYATVTIATTGVGKLTPGFHGLHIHQVGKCEPNSVAPTGGAPGNFLSAGGHYHVPGHTGTPASGDLASLQVRGDGSAMLVTTTDAFTMDDLLSGAKTAIIIHAGADNFANIPPERYVQVNGTPGPDETTLTTGDAGKRVACGVIGSG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sodC mutant is more susceptible to killing by activated murine macrophages than the wild type (Piddington et al., 2001).
COG COG2032P, under P: Inorganic ion transport and metabolism
References
Piddington et al., 2001: Piddington DL, Fang FC, Laessig T, Cooper AM, Orme IM, Buchmeier NA. Cu,Zn superoxide dismutase of Mycobacterium tuberculosis contributes to survival in activated macrophages that are generating an oxidative burst. Infection and immunity. 2001; 69(8); 4980-4987. [PubMed: 11447176].