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relA from Yersinia pestis Nepal516

Victor ID 1815
Gene Name relA from Yersinia pestis Nepal516
Sequence Strain (Species/Organism) Yersinia pestis Nepal516
NCBI Gene ID 4123547
NCBI Protein GI 108810878
Locus Tag YPN_0713
Protein Accession YP_646645.1
Other Database IDs UniProtKB-ID: Q1CLT5_YERPN
UniRef100: UniRef100_A4TPX8
UniRef90: UniRef90_A4TPX8
UniRef50: UniRef50_P55133
UniParc: UPI00000DC624
EMBL: CP000305
EMBL: ACNQ01000007
EMBL-CDS: ABG17045.1
EMBL-CDS: EEO77905.1
RefSeq_NT: NC_008149.1
GenomeReviews: CP000305_GR
KEGG: ypn:YPN_0713
eggNOG: COG0317
HOGENOM: HBG594146
OMA: DLGHRCR
ProtClustDB: PRK10872
BioCyc: YPES377628:YPN_0713-MONOMER
Taxonomy ID 377628
Gene Starting Position 836576
Gene Ending Position 838810
Gene Strand (Orientation) +
Protein Name GDP/GTP pyrophosphokinase
DNA Sequence 
>gi|108810166:836576-838810 Yersinia pestis Nepal516, complete genome
TATGGTTGCGGTACGAAGTGCGCATTTAAACCCAGCGGGTGAGTTTGCTCTTGACGATTGGATTGCCAGT
TTAGGGCTTGCCAATCCGCAGTCATCTGAGCGATTAGCCGAAACCTGGCGTTACTGTGAACAACAGACGC
AAAACCATCCCGATGCCTCGTTATTACTGTGGCGCGGTCTTGAAATGGTTGAAATTCTTTCCACTCTGAG
TATGGATAACGACAGTATGCGCGCGGCGCTGCTGTTCCCGCTGGTAGATGCCAATATCGTGGACGAAACT
ACCCTGACCGAGCAATTCGGTAAGGGGATTACGTATCTGGTACACGGCGTGCGTGATATGGATGCTATCC
GCCAGTTAAAAGCCACTCACAACGATTCCATGAGCTCGGAGCAAGTGGATAACGTGCGCCGTATGTTATT
GGCGATGGTGGAGGATTTCCGCTGCGTGGTGATCAAGCTGGCAGAGCGGATCGCTCATCTGCGTGAAGTC
AAAGATGCACCGGAAGATGAACGTGTTCTGGCGGCTAAAGAGTGTTCCAATATTTACGCACCACTGGCGA
ACCGTTTGGGGATTGGCCAGATTAAATGGGAGCTGGAGGATTTCTGCTTCCGTTATCTGCATCCAGATGA
ATATAAGAAAATCGCCAAATTACTCCACGAGAGGCGTATTGATCGCGAACAATTTATTGATGACTTCGTT
GCTTCATTACATAAGGCGATGGCCGACGAAGGCATTAAAGCCGACATTTATGGCCGACCGAAGCATATCT
ACAGCATTTGGCGCAAAATGCAGAAAAAGTCGCTGGCCTTCGATGAGCTATTCGACGTCCGCGCGGTGCG
GGTGGTGGTGGAACGTTTGCAGGATTGTTATGCCGCGTTAGGGATTGTTCACACGCACTTCCGGCATTTA
CCTGATGAATTTGATGATTATGTGGCCAACCCTAAGCCAAATGGTTACCAATCGATCCATACCGTGGTGC
TTGGGCCACGAGGTAAAACGTTAGAGATTCAGATCCGCACCCGCCAGATGCATGAAGATGCCGAGTTGGG
GGTTGCTGCGCACTGGAAATATAAAGAAGGGGCCGTGGCAGCGGGCCGTTCGAGTTATGAAGGGCGAATC
GCCTGGTTACGTAAATTGATCGCTTGGCAGGAAGAGATGGCTGATTCTGGCGAAATGCTGGATGAAGTGC
GCAGCCAGGTATTTGATGATCGGGTGTACGTGTTTACACCGAAAGGCGATGTGATTGACCTGCCTGCCGG
CTCGACGCCGCTGGATTTTGCCTACCATATTCATAGCGATGTGGGCCACCGTTGTATCGGTGCCAAAATC
AGTGGCCGCATTGTGCCGTTTACTTATCAGTTGCAGATGGGTGATCAAATTGAAATTATCACTCAAAAAC
AGCCAAACCCAAGCCGTGACTGGCTGAATCCTAACCTCGGTTACATCACGACCAGTCGCGGACGTTCCAA
AATTCATAACTGGTTCCGCAAACAAGATAGAGATAAGAATATTCTGGCTGGCCGGCAAATGCTGGATGAT
GAGCTGGAGCATCTGGATATCAGTCTGAAAGAGGCTGAGAAGCTGCTTGTTCCGCGTTACAACATGAATT
CGATGGATGAAGTGTTAGCGGCGATTGGGGGGGGTGATATCCGTCTGAATCAGATGGTGAACTTCCTCCA
GGGCAAACTGAATAAGCCAACGGCAGAAGAGGCTGATCTAGAAGCACTCCGTCATCTGAATAACAAGCAT
CAGCCCGCGCCACGTAACGCCAGCAAAGACAGTGGGCGTATTGTGGTCGAAGGTGTCGGTAACCTGATGC
ACCATATTGCCCGTTGTTGCCAGCCGATCCCCGGTGATCAAATTATCGGTTTTATCACGCAAGGGCGGGG
GATATCGATTCACCGTGCAGATTGTGAGCAGTTGGCTGAATTGGAATCCCATGCACCGGAACGGATTGTC
GATGCAGTCTGGGGCGAAAGCTACTCCAGCGGTTATTCGCTGGTGGTGCGGGTTACGGCTAATGACCGCA
GTGGGTTATTGCGCGATATCACTACGATCCTGGCAAATGAGAAAGTTAACGTACTGGGCGTTGCCAGCCG
CAGCGATACCAAAAAGATGGTGGCGACTATCGATATGGATATCGAGATCTATAACTTGCAGGTGCTGGGC
CGGGTATTGGCCAAACTGAATCAGTTGCCGGATGTCATAGACGCCCGTCGCCTCCATGGCAATTA
Protein Sequence 
>gi|108810878|ref|YP_646645.1| GDP/GTP pyrophosphokinase [Yersinia pestis Nepal516] MVAVRSAHLNPAGEFALDDWIASLGLANPQSSERLAETWRYCEQQTQNHPDASLLLWRGLEMVEILSTLSMDNDSMRAALLFPLVDANIVDETTLTEQFGKGITYLVHGVRDMDAIRQLKATHNDSMSSEQVDNVRRMLLAMVEDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECSNIYAPLANRLGIGQIKWELEDFCFRYLHPDEYKKIAKLLHERRIDREQFIDDFVASLHKAMADEGIKADIYGRPKHIYSIWRKMQKKSLAFDELFDVRAVRVVVERLQDCYAALGIVHTHFRHLPDEFDDYVANPKPNGYQSIHTVVLGPRGKTLEIQIRTRQMHEDAELGVAAHWKYKEGAVAAGRSSYEGRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVIDLPAGSTPLDFAYHIHSDVGHRCIGAKISGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYITTSRGRSKIHNWFRKQDRDKNILAGRQMLDDELEHLDISLKEAEKLLVPRYNMNSMDEVLAAIGGGDIRLNQMVNFLQGKLNKPTAEEADLEALRHLNNKHQPAPRNASKDSGRIVVEGVGNLMHHIARCCQPIPGDQIIGFITQGRGISIHRADCEQLAELESHAPERIVDAVWGESYSSGYSLVVRVTANDRSGLLRDITTILANEKVNVLGVASRSDTKKMVATIDMDIEIYNLQVLGRVLAKLNQLPDVIDARRLHGN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: relA spoT deletion mutants are attenuated in mice (Sun et al., 2009).
COG COG0317TK, under T: Signal transduction mechanisms; K: Transcription
References
Sun et al., 2009: Sun W, Roland KL, Branger CG, Kuang X, Curtiss R 3rd. The role of relA and spoT in Yersinia pestis KIM5 pathogenicity. PloS one. 2009; 4(8); e6720. [PubMed: 19701461].