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tonB from Shigella flexneri 5 str. 8401

Victor ID 1805
Gene Name tonB from Shigella flexneri 5 str. 8401
Sequence Strain (Species/Organism) Shigella flexneri 5 str. 8401
NCBI Gene ID 4209759
NCBI Protein GI 110805256
Locus Tag SFV_1266
Protein Accession YP_688776.1
Other Database IDs UniProtKB-ID: Q0T5E4_SHIF8
UniRef100: UniRef100_Q0T5E4
UniRef90: UniRef90_P02929
UniRef50: UniRef50_P25945
UniParc: UPI0000DB294F
EMBL: CP000266
EMBL-CDS: ABF03471.1
RefSeq_NT: NC_008258.1
EnsemblGenome: EBESCG00000095196.
EnsemblGenome_TRS: EBESCT00000096152
EnsemblGenome_PRO: EBESCP00000092348
GenomeReviews: CP000266_GR
KEGG: sfv:SFV_1266
eggNOG: COG0810
HOGENOM: HBG473783
OMA: MIMTSIT
ProtClustDB: PRK10819
BioCyc: SFLE373384:SFV_1266-MONOMER
Taxonomy ID 373384
Gene Starting Position 1321276
Gene Ending Position 1322058
Gene Strand (Orientation) +
Protein Name membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins
DNA Sequence 
>gi|110804074:1321276-1322058 Shigella flexneri 5 str. 8401, complete genome
TTTGCATTTAAAATCGAGGCCTAGTTTTTCTACTGAAATGATTATGACTTCAATAACCCTTGATTTACCT
CGCCGCTTCCCCTGGCCGACGTTACTTTCGGTCTGCATTCATGGTGCTGTTGTGGCGGGGCTGCTCTATA
CCTCGGTACATCAGGTTATTGAACTACCTGCGCCTGCGCAACCAATTTCTGTCACGATGGTTGCGCCTGC
TGATCTCGAACCGCCACAAGCCGTTCAGCCGCCACCGGAGCCGGTGGTAGAGCCAGAACCGGAACCTGAG
CCGATCCCCGAACCGCCAAAAGAAGCACCGGTGGTCATTGAAAAGCCGAAGCCGAAACCTAAGCCAAAAC
CGAAGCCAAAACCGAAGCCGGTGAAAAAGGTACAGGAGCAGCCAAAACGCGATGTCAAACCCGTAGAGTC
GCGTCCGGCATCACCGTTTGAAAATACGGCACCCGCGCGCCCCACATCAAGTACGGCAACGGCTGCAACC
AGCAAGCCGGTTACCAGTGTGGCTTCAGGACCACGCGCATTAAGCCGTAATCAGCCGCAGTATCCGGCAC
GAGCACAGGCATTGCGCATTGAAGGGCAGGTTAAAGTTAAATTTGACGTCACGCCGGATGGTCGCGTGGA
TAACGTACAAATCCTCTCAGCCAAGCCTGCGAACATGTTTGAGCGTGAGGTGAAAAATGCGATGCGCAGA
TGGCGTTATGAGCCGGGTAAGCCAGGCAGTGGGATTGTGGTGAATATCCTGTTTAAAATTAACGGCACCA
CCGAAATTCAGTA
Protein Sequence 
>gi|110805256|ref|YP_688776.1| transport protein TonB [Shigella flexneri 5 str. 8401] MHLKSRPSFSTEMIMTSITLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tonB mutant is able to invade epithelial cells but is incapable of cell to cell spread (Reeves et al., 2000).
COG COG0810M, under M: Cell wall/membrane/envelope biogenesis
References
Reeves et al., 2000: Reeves SA, Torres AG, Payne SM. TonB is required for intracellular growth and virulence of Shigella dysenteriae. Infection and immunity. 2000; 68(11); 6329-6336. [PubMed: 11035742].