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dsbA from Shigella flexneri 5 str. 8401

Victor ID 1800
Gene Name dsbA from Shigella flexneri 5 str. 8401
Sequence Strain (Species/Organism) Shigella flexneri 5 str. 8401
NCBI Gene ID 4208998
NCBI Protein GI 110807455
Locus Tag SFV_3641
Protein Accession YP_690975.1
Other Database IDs UniProtKB-ID: Q0SZ45_SHIF8
UniRef100: UniRef100_P0AEG5
UniRef90: UniRef90_P0A4L6
UniRef50: UniRef50_P0A4L6
UniParc: UPI000002D10B
EMBL: CP000266
EMBL-CDS: ABF05670.1
RefSeq_NT: NC_008258.1
EnsemblGenome: EBESCG00000095453.
EnsemblGenome_TRS: EBESCT00000096409
EnsemblGenome_PRO: EBESCP00000092605
GenomeReviews: CP000266_GR
KEGG: sfv:SFV_3641
eggNOG: COG0526
HOGENOM: HBG680642
OMA: PAMYVNG
ProtClustDB: PRK10954
BioCyc: SFLE373384:SFV_3641-MONOMER
Taxonomy ID 373384
Gene Starting Position 3726935
Gene Ending Position 3727561
Gene Strand (Orientation) -
Protein Name periplasmic protein disulfide isomerase I
DNA Sequence 
>gi|110804074:3726935-3727561 Shigella flexneri 5 str. 8401, complete genome
ATTATTTTTTCTCGGACAGATATTTCACCGTATCAGCATACTGCTGAACAAAAACATCCATATTGCTGGT
ATCCATACCCTGCGGATTCAGCTGATATTTACCGTTAACAAACATCGCCGGAACACCACGCAATTGCACA
TCAGCTGCGGCTTTTTCCTGCTGAGCGACCAGAGATTTCACCACGAAGCTGTTCCACGCCGCGTCGTACT
CTTCACCTTTAATACCTGCATTGATAAATACATCGCGGATATCAGATGCTGAACGAATGGTCTGGGTTTT
CTGTACGCCTTCAAACAGCGGAACAGTCACTTTGTCTTCCACGCCCAGCGCCATCGCCACAGCCCATGCC
TGAGTCAGATCTTTGCCCAGGTCACCACCCATGAAGTTGACGTGGTATTTAGTCATCTTCACGCCTTCCG
GCAGTTTTTTCTTCACATTATCAGAAATATGCAGAACTTCTTCAAACTGATAGCAGTGCGGGCAGAAGAA
AGAGAAAAACTCCAGCACTTGCGGCGCGCCAGCTACCGGTTTTTCCAGGGTAGTGTACTGTTTACCATCT
TCATACTGCGCCGCCGATGCGCTAAACGCTAAAACTAAACCAGCCAGCGCCAGCCAAATCTTTTTCA
Protein Sequence 
>gi|110807455|ref|YP_690975.1| periplasmic protein disulfide isomerase I [Shigella flexneri 5 str. 8401] MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dsbA mutants are less invasive to MK-2 cell monolayers compared to the wild-type (Watarai et al., 1995).
COG COG1651O, under O: Posttranslational modification, protein turnover, chaperones
References
Watarai et al., 1995: Watarai M, Tobe T, Yoshikawa M, Sasakawa C. Disulfide oxidoreductase activity of Shigella flexneri is required for release of Ipa proteins and invasion of epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 1995; 92(11); 4927-4931. [PubMed: 7761426].