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bioA

Victor ID 180
Gene Name bioA
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886343
NCBI Protein GI 15608706
Locus Tag Rv1568
Protein Accession NP_216084.1
Other Database IDs UniProtKB-ID: BIOA_MYCTU
UniRef100: UniRef100_P0A4X7
UniRef90: UniRef90_P0A4X7
UniRef50: UniRef50_P0A4X7
UniParc: UPI0000126955
EMBL: BX842577
EMBL: AE000516
EMBL-CDS: CAB09069.1
EMBL-CDS: AAK45886.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 3BV0
PDB: 3LV2
EnsemblGenome: EBMYCG00000000100
EnsemblGenome_TRS: EBMYCT00000000100
EnsemblGenome_PRO: EBMYCP00000000100
EnsemblGenome: EBMYCG00000070204
EnsemblGenome_TRS: EBMYCT00000070209
EnsemblGenome_PRO: EBMYCP00000068268
GenomeReviews: AE000
Taxonomy ID 83332
Gene Starting Position 1775391
Gene Ending Position 1776704
Gene Strand (Orientation) +
Protein Name adenosylmethionine--8-amino-7-oxononanoate transaminase
DNA Sequence 
>gi|57116681:1775391-1776704 Mycobacterium tuberculosis H37Rv, complete genome
CATGGCTGCGGCGACTGGCGGGTTGACGCCCGAGCAGATCATCGCGGTCGATGGCGCCCATCTGTGGCAC
CCTTACAGCTCCATCGGCAGGGAAGCCGTGTCGCCGGTGGTGGCCGTCGCCGCCCACGGAGCGTGGTTGA
CGCTGATTCGCGACGGCCAGCCGATCGAGGTGCTCGACGCGATGAGCTCCTGGTGGACCGCGATCCACGG
GCACGGCCACCCCGCTCTGGACCAGGCGTTAACCACCCAGTTGCGGGTGATGAACCACGTCATGTTCGGG
GGGCTGACTCACGAGCCGGCGGCCCGGCTGGCGAAGCTGCTGGTCGACATCACCCCGGCGGGTCTCGACA
CGGTGTTCTTCAGCGACTCCGGCTCGGTGTCGGTGGAAGTCGCGGCCAAGATGGCGCTGCAGTACTGGCG
CGGCCGCGGCCTGCCCGGCAAGCGACGGCTCATGACCTGGCGCGGCGGCTATCACGGCGACACCTTCCTG
GCTATGAGCATCTGCGACCCGCACGGCGGCATGCACTCGCTGTGGACCGACGTCCTGGCCGCCCAAGTGT
TCGCGCCACAAGTGCCACGGGACTACGATCCCGCCTACAGCGCGGCGTTCGAGGCGCAGCTGGCGCAGCA
CGCCGGCGAGCTGGCCGCGGTGGTCGTGGAGCCGGTCGTGCAGGGTGCGGGCGGTATGCGTTTTCACGAC
CCGCGCTATCTGCACGACCTGCGGGACATCTGCCGCCGTTACGAGGTGCTGCTGATCTTCGATGAGATCG
CCACCGGCTTCGGCCGCACCGGCGCGTTGTTCGCCGCCGACCACGCCGGGGTGAGCCCGGACATCATGTG
TGTCGGCAAGGCGCTCACCGGCGGCTACCTCAGCTTGGCCGCCACCTTGTGCACCGCCGACGTCGCGCAC
ACCATCAGCGCCGGTGCGGCCGGGGCGCTGATGCACGGCCCCACCTTCATGGCCAATCCGCTGGCCTGTG
CGGTCTCGGTGGCCAGTGTGGAGCTGCTGCTCGGCCAGGACTGGCGCACGCGCATCACCGAACTGGCCGC
CGGGCTGACCGCCGGCCTGGATACCGCCCGGGCGCTGCCCGCCGTCACCGATGTGCGGGTGTGCGGCGCG
ATCGGCGTCATCGAATGCGACCGACCGGTCGACCTGGCCGTCGCGACTCCCGCGGCGCTGGATCGAGGCG
TGTGGCTGCGCCCGTTTCGCAACCTGGTCTACGCCATGCCGCCCTATATCTGCACACCGGCCGAGATCAC
GCAGATCACCTCGGCGATGGTCGAGGTCGCACGGCTCGTAGGCTCACTGCCATG
Protein Sequence 
>gi|15608706|ref|NP_216084.1| adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Mycobacterium tuberculosis H37Rv] MAAATGGLTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGSLP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0161H, under H: Coenzyme transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].