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miaA from Shigella flexneri 5 str. 8401

Victor ID 1794
Gene Name miaA from Shigella flexneri 5 str. 8401
Sequence Strain (Species/Organism) Shigella flexneri 5 str. 8401
NCBI Gene ID 4208270
NCBI Protein GI 110808089
Locus Tag SFV_4329
Protein Accession YP_691609.1
Other Database IDs UniProtKB-ID: MIAA_SHIF8
UniRef100: UniRef100_A7ZV40
UniRef90: UniRef90_A8AMN0
UniRef50: UniRef50_Q7U347
UniParc: UPI000012F0BD
EMBL: CP000266
EMBL-CDS: ABF06304.1
RefSeq_NT: NC_008258.1
EnsemblGenome: EBESCG00000094166
EnsemblGenome_TRS: EBESCT00000095122
EnsemblGenome_PRO: EBESCP00000091318
GenomeReviews: CP000266_GR
KEGG: sfv:SFV_4329
eggNOG: COG0324
HOGENOM: HBG559459
ProtClustDB: PRK00091
BioCyc: SFLE373384:SFV_4329-MONOMER
Taxonomy ID 373384
Gene Starting Position 4471968
Gene Ending Position 4472873
Gene Strand (Orientation) +
Protein Name tRNA delta(2)-isopentenylpyrophosphate transferase
DNA Sequence 
>gi|110804074:4471968-4472873 Shigella flexneri 5 str. 8401, complete genome
GATGGGGCCGACGGCCTCCGGTAAAACGGCGTTAGCCATTGAGCTGCGTAAAATTTTACCAGTAGAGTTG
ATAAGCGTTGATTCTGCCCTTATTTACAAAGGGATGGATATCGGGACGGCGAAGCCGAACGCTGAAGAGT
TACTCGCCGCGCCGCACCGATTGCTGGATATTCGCGATCCGTCGCAGGCTTACTCGGCTGCTGATTTTCG
CCGCGATGCGCTGGCGGAAATGGCCGATATCACCGCGGCGGGGCGGATCCCACTGTTAGTGGGCGGTACG
ATGTTGTATTTCAAGGCATTGCTGGAAGGGTTGTCGCCGCTACCGTCGGCAGACCCGGAAGTGCGGGCCA
GAATTGAGCAACAGGCGGCAGAGCAAGGTTGGGAGTCATTGCATCGTCAACTTCAGGAGGTAGATCCGGT
TGCGGCAGCAAGGATTCATCCAAATGATCCACAAAGGCTTTCCCGGGCACTGGAAGTTTTTTTCATTTCG
GGTAAAACTTTAACGGAACTGACGCAAACGTCAGGAGACGCTCTACCGTATCAGGTGCATCAGTTCGCCA
TCGCCCCGGCGAGCCGTGAACTGCTCCATCAACGCATTGAGCAGCGTTTTCATCAGATGTTGGCTTCAGG
TTTTGAAGCAGAAGTCCGGGCGCTTTTTGCCCGAGGAGATTTGCATACGGACTTGCCTTCCATTCGTTGC
GTGGGTTATCGCCAGATGTGGTCTTACCTTGAAGGCGAAATCTCATACGATGAAATGGTTTATCGAGGTG
TTTGCGCCACGAGACAGTTGGCGAAGCGGCAGATAACCTGGCTGCGTGGTTGGGAAGGGGTTCACTGGCT
TGACAGTGAAAAACCAGAACAGGCGCGTGACGAAGTATTACAGGTTGTTGGTGCTATCGCAGGCTG
Protein Sequence 
>gi|110808089|ref|YP_691609.1| tRNA delta(2)-isopentenylpyrophosphate transferase [Shigella flexneri 5 str. 8401] MGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: miaA mutants had reduced ability to invade and spread in MK2 cell monolayers compared to the wildtype (Durand et al., 1997).
COG COG0324J, under J: Translation, ribosomal structure and biogenesis
References
Durand et al., 1997: Durand JM, Björk GR, Kuwae A, Yoshikawa M, Sasakawa C. The modified nucleoside 2-methylthio-N6-isopentenyladenosine in tRNA of Shigella flexneri is required for expression of virulence genes. Journal of bacteriology. 1997; 179(18); 5777-5782. [PubMed: 9294434].