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aroA from Shigella flexneri 5 str. 8401

Victor ID 1793
Gene Name aroA from Shigella flexneri 5 str. 8401
Sequence Strain (Species/Organism) Shigella flexneri 5 str. 8401
NCBI Gene ID 4208207
NCBI Protein GI 110804915
Locus Tag SFV_0908
Protein Accession YP_688435.1
Other Database IDs UniProtKB-ID: AROA_SHIF8
UniRef100: UniRef100_Q0SX08
UniRef90: UniRef90_A8AIH5
UniRef50: UniRef50_B1JXR9
UniParc: UPI000000E04D
EMBL: CP000266
EMBL-CDS: ABF03130.1
RefSeq_NT: NC_008258.1
EnsemblGenome: EBESCG00000095648
EnsemblGenome_TRS: EBESCT00000096604
EnsemblGenome_PRO: EBESCP00000092800
GenomeReviews: CP000266_GR
KEGG: sfv:SFV_0908
eggNOG: COG0128
HOGENOM: HBG646626
OMA: GADIEWG
ProtClustDB: PRK02427
BioCyc: SFLE373384:SFV_0908-MONOMER
Taxonomy ID 373384
Gene Starting Position 948100
Gene Ending Position 949383
Gene Strand (Orientation) +
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
DNA Sequence 
>gi|110804074:948100-949383 Shigella flexneri 5 str. 8401, complete genome
CATGGAATCCCTGACGTTACAACCCATCGCTCGTGTCGATGGCACTATTAATCTGCCCGGTTCCAAGAGC
GTTTCTAACCGCGCTTTATTGCTTGCGGCATTAGCACACGGCAAAACAGTATTAACCAATCTGCTGGATA
GCGACGACGTGCGCCATATGCTGAATGCATTAACAGCGTTAGGGTTAAGCTATACGCTTTCAGCCGATCG
TACGCGTTGCGAAATTATCGGTAACGGCGGTCCATTACACGCAGAAGGTGCCCTGGAGTTGTTCCTCGGT
AACGCCGGAACGGCAATGCGTCCGCTGGCGGCAGCTCTTTGTCTGGATAGCAATGATATTGTGCTGACCG
GTGAGCCGCGTATGAAAGAGCGCCCGATTGGTCATCTGGTGGATGCGCTGCGCCTGGGCGGGGCGAAGAT
CACTTACCTGGAACAAGAAAATTATCCGCCGTTGCGTTTACAGGGCGGCTTTACTGGCGGCAACGTTGAC
GTTGATGGCTCCGTTTCCAGCCAATTCCTCACCGCACTGTTAATGACTGCGCCTCTTGCGCCGGAAGATA
CGGTGATTCGTATTAAAGGCGATCTGGTTTCTAAACCTTATATCGACATCACACTCAATCTGATGAAGAC
GTTTGGTGTTGAAATTGAAAATCAGCACTATCAACAATTTGTCGTAAAAGGCGGGCAGTCTTATCAGTCT
CCGGGTACTTATTTGGTCGAAGGCGATGCATCTTCGGCTTCTTACTTTCTGGCAGCAGCAGCAATCAAAG
GCGGCACTGTAAAAGTGACCGGTATTGGACGTAACAGTATGCAGGGTGATATTCGCTTTGCTGATGTGCT
GGAAAAAATGGGCGCGACCATTTGCTGGGGCGATGATTATATTTCCTGCACGCGTGGTGAACTGAACGCT
ATTGATATGGATATGAACCATATTCCTGATGCGGCGATGACCATTGCCACGGCGGCGTTATTTGCAAAAG
GCACCACCACGCTGCGCAATATCTATAACTGGCGTGTTAAAGAGACCGATCGCCTGTTTGCGATGGCAAC
AGAACTGCGTAAAGTCGGCGCGGAAGTGGAAGAGGGGCACGATTACATTCGTATCACTCCTCCGGAAAAA
CTGAACTTTGCCGAGATCGCGACATACAATGATCACCGGATGGCGATGTGTTTCTCGCTGGTGGCGTTGT
CAGATACACCAGTGACGATTCTTGATCCCAAATGCACGGCCAAAACATTTCCGGATTATTTCGAGCAGCT
GGCGCGGATTAGCCAGGCAGCCTG
Protein Sequence 
>gi|110804915|ref|YP_688435.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Shigella flexneri 5 str. 8401] MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGLSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLDSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroA deletion mutants are attenuated in HeLa cells (Noriega et al., 1996).
COG COG0128E, under E: Amino acid transport and metabolism
References
Noriega et al., 1996: Noriega FR, Losonsky G, Lauderbaugh C, Liao FM, Wang JY, Levine MM. Engineered deltaguaB-A deltavirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine. Infection and immunity. 1996; 64(8); 3055-3061. [PubMed: 8757833].