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envZ from Shigella flexneri 5 str. 8401

Victor ID 1791
Gene Name envZ from Shigella flexneri 5 str. 8401
Sequence Strain (Species/Organism) Shigella flexneri 5 str. 8401
NCBI Gene ID 4207729
NCBI Protein GI 110807236
Locus Tag SFV_3409
Protein Accession YP_690756.1
Other Database IDs UniProtKB-ID: Q0SZR4_SHIF8
UniRef100: UniRef100_P0AEJ4
UniRef90: UniRef90_P0AEJ4
UniRef50: UniRef50_P0AEJ4
UniParc: UPI0000000AFB
EMBL: CP000266
EMBL-CDS: ABF05451.1
RefSeq_NT: NC_008258.1
EnsemblGenome: EBESCG00000093950.
EnsemblGenome_TRS: EBESCT00000094906
EnsemblGenome_PRO: EBESCP00000091102
GenomeReviews: CP000266_GR
KEGG: sfv:SFV_3409
eggNOG: COG0642
HOGENOM: HBG334875
OMA: KPSYQQI
ProtClustDB: PRK09467
BioCyc: SFLE373384:SFV_3409-MONOMER
Taxonomy ID 373384
Gene Starting Position 3465716
Gene Ending Position 3467068
Gene Strand (Orientation) -
Protein Name osmolarity sensor protein
DNA Sequence 
>gi|110804074:3465716-3467068 Shigella flexneri 5 str. 8401, complete genome
TTTACCCTTCTTTTGTCGTGCCCTGCGCCCGCGTTACCGGCACTGGCAGCCAGGCGCGAATGGAAAGCCC
GCCCCGCTCGCTGGTGCCAAGCTCCAGCATCCCGTTATGGTTATCCACGATACGCTGCACAATTGCCAGC
CCTAATCCCGTGCCGCTAATGGTGCGCGCACTGTCGCCGCGGACAAACGGCTGGAACAGGTGCTTACGTT
GTTCCGGCGCAATTCCCGGACCGTCATCTTCCACCTGGAACCAGGCGCGATTCGGCTCCGTTCCGCTGCT
GACTTTGATCCAGCCATTGCCATAACGGGCGGCGTTGACCACCATATTCGCCACCGCGCGTTTGATCGAC
AGCGGGTGCATTTTCACTTCAATGCTGCCGGGGTAAAGCGCGGTTTCAATTTCCCGCTCATAGCCACTTT
CGGCAGCAATCACCTCACCGAGCACTGCATTAAGATCCGCCATTTCCATCGGCATCTCCTGCCCGGTGCG
CAGGTAGTCGATAAACTGCTCAATGATGGCGTTGCACTCTTCGATATCTTTATTGATCGATTCTGCCAGA
TAGCCATCCTGCTCGCTCATCATCTCAGTCGCCAGGCGAATACGCGTCAGCGGCGTGCGCAAGTCGTGAC
TTACCCCCGCCATCAGCAGCGTGCGGTCATCCGCCAGTTGCTTAACACCAGCCGCCATATGGTTAAAGGC
ACGGGTAACGGAACGCACCTCCGAAGCGCCATATTCACGCAGCGGCGGCGGAATAATCCCTTTACCAACC
TGCAAGGCTGCGTGTTCGAGATCGACCAACGGTCGGTTCTGGATACGAATAAACAGCCACGCCCCGCCTA
TCGCCAATAGCATAATCGCCAGCGTATAGCGGAACAGCGGAGAGAAATCGCCCTGATGAATTTCGGTCAG
CGGCACGCGTACCCAGATATTGGGCGACAGCCAGGTTTTCAGCCAGACGACAGGCGAACTTTTGTTGACC
TCAACGCGCACTTCCGTCGGGCCGCCCAGTTGCTGTGCCATCTGATGGCTTAAGAATTCATAGTGTTGCG
CCCAACGCAGACCTGCCTCTTCGGCAGCCTCGTTGGAGTAGAGAGAGATCCCCAGCTCACGGTAGATCTC
CCGACGGAAAGCGGGAGGCACAACCAACTGCGTGCCGTCCTCCAGTTGCAGTTTGTCGGTCATCAACATA
CGCACTTCGTACGCGAGGACTTTATTAAACTGCTGGAGGCTCGGCAAAATCGCGAAGTTCAGCACCACCA
GATAAGTCGTCACCAGGCTGGCGAACAGCAAGGTGACGATGAGCAATAACGTACGGGCAAATGAACTTCG
TGGCGAGAAGCGCAATCGCCTCA
Protein Sequence 
>gi|110807236|ref|YP_690756.1| osmolarity sensor protein [Shigella flexneri 5 str. 8401] MRRLRFSPRSSFARTLLLIVTLLFASLVTTYLVVLNFAILPSLQQFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWAQHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPLFRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTRAFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHPLSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVRGDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: envZ insertion mutant is able to invade cells but has decreased virulence due to the inability to survive intracellularly (Bernardini et al., 1990).
COG COG0642T, under T: Signal transduction mechanisms
References
Bernardini et al., 1990: Bernardini ML, Fontaine A, Sansonetti PJ. The two-component regulatory system ompR-envZ controls the virulence of Shigella flexneri. Journal of bacteriology. 1990; 172(11); 6274-6281. [PubMed: 2121709].