Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

bioB

Victor ID 179
Gene Name bioB
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886301
NCBI Protein GI 15608727
Locus Tag Rv1589
Protein Accession NP_216105.1
Other Database IDs UniProtKB-ID: BIOB_MYCTU
UniRef100: UniRef100_A1KJ05
UniRef90: UniRef90_A1KJ05
UniRef50: UniRef50_A8L2N0
UniParc: UPI0000126961
EMBL: BX842577
EMBL: AE000516
EMBL-CDS: CAB09080.1
EMBL-CDS: AAK45892.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000000433
EnsemblGenome_TRS: EBMYCT00000000433
EnsemblGenome_PRO: EBMYCP00000000433
EnsemblGenome: EBMYCG00000069916
EnsemblGenome_TRS: EBMYCT00000069921
EnsemblGenome_PRO: EBMYCP00000067980
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 1790283
Gene Ending Position 1791332
Gene Strand (Orientation) +
Protein Name biotin synthase
DNA Sequence 
>gi|57116681:1790283-1791332 Mycobacterium tuberculosis H37Rv, complete genome
GGTGACGCAAGCGGCAACGCGACCGACGAACGACGCCGGCCAGGATGGCGGGAACAACTCGGACATTCTG
GTGGTTGCCCGCCAACAGGTGCTGCAGCGCGGTGAGGGCCTGAACCAGGACCAGGTGCTGGCGGTGCTGC
AGCTACCCGACGACCGGCTCGAGGAGCTGTTGGCGCTGGCCCACGAGGTGCGGATGCGCTGGTGCGGACC
CGAGGTCGAGGTCGAAGGCATCATCAGCCTGAAAACCGGTGGCTGCCCGGAGGATTGCCATTTCTGCTCG
CAATCGGGGCTGTTCGCCTCCCCGGTGCGCAGCGCCTGGCTGGACATACCCAGCCTGGTCGAGGCGGCCA
AACAGACCGCCAAGTCCGGCGCCACCGAGTTCTGCATCGTGGCCGCGGTGCGCGGACCCGACGAGCGATT
GATGGCCCAGGTCGCGGCCGGCATCGAGGCGATTCGCAACGAAGTCGAGATCAACATCGCCTGCTCCCTA
GGGATGCTGACCGCCGAGCAAGTGGACCAACTGGCGGCGAGGGGGGTGCATCGCTACAACCACAACCTCG
AAACGGCGCGCTCGTTCTTCGCCAACGTCGTCACCACCCACACCTGGGAAGAGCGCTGGCAGACGCTATC
GATGGTGCGTGACGCGGGCATGGAGGTTTGCTGCGGCGGCATCCTCGGCATGGGGGAGACGCTGCAGCAG
CGCGCGGAATTCGCCGCCGAGCTTGCCGAGCTGGGCCCCGACGAGGTCCCGCTGAACTTCCTCAACCCGC
GGCCCGGTACCCCGTTCGCCGACCTGGAGGTAATGCCGGTCGGTGACGCGCTCAAGGCGGTGGCCGCCTT
CCGGTTGGCGTTACCGCGCACCATGCTGCGGTTCGCCGGTGGCCGCGAGATCACCCTGGGTGACCTCGGC
GCCAAGCGAGGCATCCTGGGCGGCATCAACGCCGTGATCGTCGGCAACTACCTGACCACCCTCGGCCGGC
CCGCGGAAGCCGACCTGGAACTGCTCGACGAGCTACAGATGCCGCTGAAGGCACTCAACGCCAGCCTGTA
Protein Sequence 
>gi|15608727|ref|NP_216105.1| biotin synthetase [Mycobacterium tuberculosis H37Rv] MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0502H, under H: Coenzyme transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].