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iucA from Shigella flexneri 5 str. 8401

Victor ID 1787
Gene Name iucA from Shigella flexneri 5 str. 8401
Sequence Strain (Species/Organism) Shigella flexneri 5 str. 8401
NCBI Gene ID 4207099
NCBI Protein GI 110807649
Locus Tag SFV_3854
Protein Accession YP_691169.1
Other Database IDs UniProtKB-ID: Q0SYK1_SHIF8
UniRef100: UniRef100_Q31T55
UniRef90: UniRef90_Q47316
UniRef50: UniRef50_Q47316
UniParc: UPI00005AAB11
EMBL: CP000266
EMBL-CDS: ABF05864.1
RefSeq_NT: NC_008258.1
EnsemblGenome: EBESCG00000096332.
EnsemblGenome_TRS: EBESCT00000097288
EnsemblGenome_PRO: EBESCP00000093484
GenomeReviews: CP000266_GR
KEGG: sfv:SFV_3854
eggNOG: COG4264
HOGENOM: HBG578705
OMA: SFLNCYL
ProtClustDB: CLSK908239
BioCyc: SFLE373384:SFV_3854-MONOMER
Taxonomy ID 373384
Gene Starting Position 3954510
Gene Ending Position 3956234
Gene Strand (Orientation) -
Protein Name siderophore biosynthesis protein
DNA Sequence 
>gi|110804074:3954510-3956234 Shigella flexneri 5 str. 8401, complete genome
TTCAGACCTCCTGAGCCTGCAGCGGGTTAGCGAAATCGAAATAGATCACCGAAGGGTCAACAATGGTGTT
CTCGTTATGATCGTTCAGATAACAGAAAAAGTTACCTTTTACGTTCCAGTACGGACTTTCCAGCACGTAG
TTGAGACAGGTTTTATGAGTCACCTGATCACGCACTTCAGCCAGCGATGCTCGTACACGAGCCATCAGAT
TCGATTCGCTGTCCAGCCCGGCAGCCCCCAGCGCAGCGGTCACAGCAAAAGTGGAGTTAACCAGCAGGTA
ATAAGGGAAATAGCGCAGCAACTGCTCATGGGTGAAAATATTTTCCGCCTGCGCCTCGCCAATAGAATCG
AGCCAGTCTGTCGCGTGAGGCATAAAAGCGCTGCCCTGACAGTCACGGTAAATAAATCCGACCGGCAGAT
CCCCAAGCATCTGGACAAGAATATTTTGCTGATGCGCCAGCAGCACCAGGCCGTAATCCGCTTCAGCCGT
AAACAGCGGCTTTAGCACTTGCTGACAGTATGCATCAACCCATGCATGGGCGGCCTGTTGCACAGTGATA
CCGAGGCGATCGCTCAGGCGTTTTACCGCCGAAACCAGCAGCGAATCACCGCCATCAGGTGCGGCCTGAG
TCAGGGAGACCAGTACGTTAGTCTGGCTTTTCGGCTGATCCACCAGCAGATTTTCACGCAGGGCAAACAG
ACTTTCCTGCATGATGTTGCCGTTAAGATCGAGCAGCCCGGCCCAGCCATCCTCCTGCATTACCCGGAAA
GTCGGGAAGCGGACCTGTAGCATCTGCCAGCCGTCGGTTTGAGCCAGGCGTGCCAGGCGCATCCCACGCT
TCACTTCTTTCACGGACAGAGTACGGATGGAGTTGGTCAGCCGTACGCTCAGGGAGAACTTGATCATATC
GCGGCTGGTGGCACAGTAGAGGGAACGGGAAGAGGTGGTCGGCAGCCACGACGTGCCGGCCTCACCTAAG
TCTTTAATCAGCCCTTTAGCAACAAGTGCCTGGCACCACCCCTGCTGCAAAAGATATTCCCCCTGCCACG
GGTGCAACGGGAACAGCCATTGGTTGTCACTTAATTCGTTGAGTAACTGAGGCGCATTCTCTGCGGCAAA
TCGCGTCAGCCGCTGTTGAAGGTTGAGATGCAAACTTTCACCGGCGATTTGCGTTTTATCCACCGAAAAC
CACCGCAGTGGGAAGTGGGGTGCCATATCAGGCAGGTAGCGTTCAGCCTCCCGCCGGTTAAACGGTTCAT
GAGACTTAGGCGCAGGGTGGAAAGCGTGTCCTGTCAGCAGCGCCTGCTCAGCCTCGCCAAAATTCAACGC
TTTTTCACGCAGAGCGGCCCAGTCATGACGGGCATCAATTGCCTGTTGCGTATGGACATGGCTTTCCAGC
ACGCGCTGGTGGAAAGTTTCGCAGAGGGGAACGGGCAGAAACAGTTGATGGCGTAGCTTATCAATAATAA
GCCGGGAGAGAGTGGTAAAGTCGACAGGATAACTGCCTGATGCCGTGACCAGACGTGCAGGAAATGCAAA
GCGGTGATGCTGGGTTGGGGAGAAATAAGCCACTCTGAAATGGAGCGATTTCTGCTCATCCAGCGGGATG
AGCAATTCGTCTGGCGGGTATTCTGTCAGTTTCCAGTCTGTGGTTTCACGAATCAGTGCATTCAGGAAGC
ACTGCGCAGCCACATCTGTGGCTGGTTTTTCAGAGGGCAGGGTCA
Protein Sequence 
>gi|110807649|ref|YP_691169.1| siderophore biosynthesis protein [Shigella flexneri 5 str. 8401] MTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVAYFSPTQHHRFAFPARLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFNRREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQALVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTFRVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYFPYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iuc mutants are attenuated in chicken embryos and rabbit ileal loops (Wyckoff et al., 2009).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Wyckoff et al., 2009: Wyckoff EE, Boulette ML, Payne SM. Genetics and environmental regulation of Shigella iron transport systems. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2009; 22(1); 43-51. [PubMed: 19130265].