Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

purH from Yersinia pestis Antiqua

Victor ID 1773
Gene Name purH from Yersinia pestis Antiqua
Sequence Strain (Species/Organism) Yersinia pestis Antiqua
NCBI Gene ID 4118909
NCBI Protein GI 108809592
Locus Tag YPA_3601
Protein Accession YP_653508.1
Other Database IDs UniProtKB-ID: PUR9_YERPA
UniRef100: UniRef100_A7FNG6
UniRef90: UniRef90_A1JIJ7
UniRef50: UniRef50_A9IZD0
UniParc: UPI00000CDA75
EMBL: CP000308
EMBL-CDS: ABG15563.1
RefSeq_NT: NC_008150.1
GenomeReviews: CP000308_GR
KEGG: ypa:YPA_3601
eggNOG: COG0138
HOGENOM: HBG498048
OMA: ASDGFFP
ProtClustDB: PRK00881
BioCyc: YPES360102:YPA_3601-MONOMER
Taxonomy ID 360102
Gene Starting Position 4038209
Gene Ending Position 4039798
Gene Strand (Orientation) +
Protein Name bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
DNA Sequence 
>gi|108805998:4038209-4039798 Yersinia pestis Antiqua chromosome, complete genome
CATGCAACAACGCCGTCCAATCCGCCGTGCTCTACTCAGTGTGTCTGACAAAGCAGGTATCATCGAATTC
GCCCAAGCACTTTCTCAACGCGGTATCGAGTTACTTTCCACCGGTGGGACTGCCCGCCTGCTGGCTGATG
CTGGTTTACCCGTTACCGAAGTGTCTGACTACACCGGTTTCCCGGAAATGATGGATGGACGTGTGAAGAC
TTTGCATCCAAAGGTGCATGGTGGGATTTTAGGTCGTCGTGGTCAGGATGATGGCATCATGGCTCAACAT
GGCATTCAGCCCATTGATATTGTCGTCGTTAATTTATATCCCTTCGCCCAGACGGTTGCCCGCCCGGATT
GCTCGTTGGAAGATGCGGTTGAGAATATTGATATTGGTGGCCCAACCATGGTTCGCTCTGCGGCCAAGAA
CCATAAAGATGTCGCCATCGTGGTGAAGAGTAGCGACTACCCCGCCATTATTACTGAGCTTGATAATAAT
GATGGTTCGTTGACTTACCCCACCCGCTTCAATCTGGCCATTAAAGCTTTCGAACACACCGCCGCCTACG
ACAGCATGATCGCCAACTACTTCGGCACACTGGTGCCACCTTATCATGGTGATACGGAACAGCCTTCCGG
CCACTTCCCTCGCACCCTAAATCTTAACTATATAAAGAAGCAGGATATGCGTTACGGTGAAAACAGCCAC
CAGCAAGCTGCCTTCTATATAGAAGAAGATGTCAAAGAGGCATCCGTTGCCACTGCCCAGCAATTACAAG
GGAAAGCCCTCTCTTATAACAATATTGCGGATACCGATGCCGCGCTGGAATGCGTGAAAGAGTTCAGTGA
ACCAGCCTGTGTGATCGTTAAACATGCCAACCCATGCGGTGTGGCTATCGGTGATTCTATTCTTGCCGCT
TATGAACGTGCCTATCAAACCGATCCAACCTCAGCTTTCGGTGGCATCATCGCCTTTAACCGTGAATTGG
ATGCAGCAACGGCCAGCGCGATCATCAGCCGCCAGTTTGTCGAAGTGATCATTGCGCCAACAGTCAGCTC
TGATGCATTGGCATTGCTTGCAGCTAAACAAAATGTCCGAGTCCTGACTTGTGGCCAGTGGCAAGCACGT
TCAGCAGGTTTAGATTTCAAACGTGTTAATGGGGGTTTGCTGGTACAAGAACGCGATTTAGGTATGGTGA
CGGCGGCCGACCTTCGCGTGGTTTCCAAGCGTCAGCCTACCGAACAGGAACTGCGTGATGCGCTGTTCTG
CTGGAAAGTGGCTAAGTTTGTTAAATCCAATGCGATTGTCTATGCCCGCGATAACATGACAATCGGTATA
GGTGCCGGCCAAATGAGCCGCGTGTACTCTGCGAAAATAGCCGGTATCAAGGCCGCAGATGAAGGGCTGG
AAGTGGCTGGCTCAGCCATGGCCTCTGATGCCTTCTTCCCGTTCCGTGATGGTATTGATGCCGCCGCGGC
TGTGGGCATTACTTGTGTCATCCAACCGGGCGGCTCAATTCGTGATGATGAAGTCATCGCGGCTGCTGAT
GAACACAGTATTGCCATGATCTTCACCGACATGCGCCATTTCCGTCATTA
Protein Sequence 
>gi|108809592|ref|YP_653508.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Yersinia pestis Antiqua] MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHSIAMIFTDMRHFRH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purH mutant is attenuated in mice (Flashner et al., 2004).
COG COG0138F, under F: Nucleotide transport and metabolism
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].