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glpK from Brucella melitensis biovar Abortus 2308

Victor ID 1769
Gene Name glpK from Brucella melitensis biovar Abortus 2308
Sequence Strain (Species/Organism) Brucella melitensis biovar Abortus 2308
NCBI Gene ID 3828238
NCBI Protein GI 0
Locus Tag BAB2_0796
Protein Accession -
Taxonomy ID 359391
Chromosome No II
Gene Starting Position 783107
Gene Ending Position 783274
Gene Strand (Orientation) +
Protein Name pseudo
DNA Sequence
>gi|83268957:783107-783274 Brucella melitensis biovar Abortus 2308 chromosome II, complete genome
AATGAGCGGATATATTCTGGCTATCGATCAGGGAACCACCTCCACAAGGTCGATGCTGTTCGACAGGAAT
ATGCGGGTCGTGGGGTTGGGGCAGCAGGAATTTACGCAGCATTTTCCTTCCTCCGGCTGGGTGGAGCACG
ATGCGGAAGAAATCTGGAAATCGGTGTA
Molecule Role Virulence factor
Molecule Role Annotation FUNCTION: Key enzyme in the regulation of glycerol uptake and metabolism(UniProt: Q8FWK8).

CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3-phosphate(UniProt: Q8FWK8).

PATHWAY: Glycerol utilization; first (rate-limiting) step(UniProt: Q8FWK8).

SIMILARITY: Belongs to the FGGY kinase family(UniProt: Q8FWK8).

MUTATION: Attenuated in Mice, Macrophages, HeLa (Delrue et al., 2004).
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].