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flgE from Brucella melitensis biovar Abortus 2308

Victor ID 1746
Gene Name flgE from Brucella melitensis biovar Abortus 2308
Sequence Strain (Species/Organism) Brucella melitensis biovar Abortus 2308
NCBI Gene ID 3827409
NCBI Protein GI 83269934
Locus Tag BAB2_1098
Protein Accession YP_419225.1
Other Database IDs UniProtKB-ID: Q2YJF9_BRUA2
UniRef100: UniRef100_O52070
UniRef90: UniRef90_O52070
UniRef50: UniRef50_O52070
UniParc: UPI00000B4FAE
EMBL: AM040265
EMBL-CDS: CAJ13264.1
RefSeq_NT: NC_007624.1
GenomeReviews: AM040265_GR
KEGG: bmf:BAB2_1098
eggNOG: COG1749
HOGENOM: HBG579156
OMA: GMSAQAN
ProtClustDB: PRK05682
BioCyc: BMEL359391:BAB2_1098-MONOMER
Taxonomy ID 359391
Chromosome No II
Gene Starting Position 1076530
Gene Ending Position 1077720
Gene Strand (Orientation) -
Protein Name flagellar hook protein FlgE
DNA Sequence 
>gi|83268957:1076530-1077720 Brucella melitensis biovar Abortus 2308 chromosome II, complete genome
CTTATCTCTTCAGATTAACCAGCACGTCCATCAGCTCGAAACCCGTCTGGAAAACCTTGGAATTGGCCGT
ATAGCTGCGCTGCGCCTCGATCATGTCGGTCAGCTCCTGCGCTATATCGGCATTGGATTCCTCCAGCGTG
CCGGACATGATCTTGCCCATGCCATCGCCCTGCGGGAAGCCAAGGCGGACATCGCCGGATTCCGCACTGG
GCAGGAATATGTTGCCGCTCACCACCGTCATGCGGTCCGGGCTTGCTACATTGGCAAGCGGAATACGGTA
GAGAACCTTCTGCGTGCCATTTTCATAGACCGCGACCACCGCACCGTCATTACCGACATCCACACCCTTG
ATGGATGAAGGCGCCTGACCGTTGATGACCGCCTGTGAAATCGTGTAATCGCCCGCACGCTGCGTGGAAC
CGCCCAGATTGAGATTGAGGGTCTGGCCACCATAGGCACCGAGATTGACCGCGACATTGCCACCGGAAAC
GAGATCGCCCGTTGTGGGATCGAAGTTCAGCACCGTCGTGCCGATCTCCACGCCATCGGCAGCGTTCTTC
ACGGAAACATTCCATTCATCCGCACCCGTCTTGGTGAAATAGACGTCGAGCGTGATCTTCTCACCCTTGT
CATTATAGGAAATGAGCGAGGTTTTGTGGTTATATCCGCCAGCCGCAGGCGCCTGATCGGTGGAAGGCAG
GTTGACGGTGAAATCGCCCGCCGTGCTTCCCTCTGCCGGCAAAGCGGCCGCGTTGACATTGACGACATTA
AGCCCCGCGACGGTCAGCCCACCCGCCGCCTCGTCCGCGCCCGCACCCAGCAGATAATAACCGGCGGAAT
TGACCAGATCGCCGTTCTTGTCCGGCACGAAAGAACCGGCCCGTGTCAGATAGGTGGAGCCGCCGGGGCC
TTGCACCACGAAATAGCCATTGCCATCAATGGCAAGATCGGTCGTGGAAGACGTGGAACGAATACCGCCC
TGATCGGAAATGCCATAGCGCACATCGGTCAGTACGCTGCCGGAATTATATTGTCCGGCAGTGCTGGGCA
GGACAAGCGAGGAGAATTGCGTTTCCGCGCGCTTGTAACCGACCGTGCTTGCATTTGCGATATTATCCGC
AACTGTCGACAAACGGTTCGCCTGAGCATTCATTCCCGAAACACCGGTCCGCATCATACCGTAGAGGCTC
A
Protein Sequence 
>gi|83269934|ref|YP_419225.1| flagellar hook protein FlgE [Brucella abortus 2308] MSLYGMMRTGVSGMNAQANRLSTVADNIANASTVGYKRAETQFSSLVLPSTAGQYNSGSVLTDVRYGISDQGGIRSTSSTTDLAIDGNGYFVVQGPGGSTYLTRAGSFVPDKNGDLVNSAGYYLLGAGADEAAGGLTVAGLNVVNVNAAALPAEGSTAGDFTVNLPSTDQAPAAGGYNHKTSLISYNDKGEKITLDVYFTKTGADEWNVSVKNAADGVEIGTTVLNFDPTTGDLVSGGNVAVNLGAYGGQTLNLNLGGSTQRAGDYTISQAVINGQAPSSIKGVDVGNDGAVVAVYENGTQKVLYRIPLANVASPDRMTVVSGNIFLPSAESGDVRLGFPQGDGMGKIMSGTLEESNADIAQELTDMIEAQRSYTANSKVFQTGFELMDVLVNLKR
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: "Classical virulence factors", Secretion of transport system, Flagella (Delrue et al., 2004).

FUNCTION: Hook (Delrue et al., 2004).

SIMILARITY: Belongs to the flagella basal body rod proteins family(UniProt: Q8FUS9).

MUTATION: Attenuated in Mice, but not in Macrophages, HeLa (Delrue et al., 2004).
COG COG1749N, under N: Cell motility
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].