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purN from Brucella melitensis biovar Abortus 2308

Victor ID 1738
Gene Name purN from Brucella melitensis biovar Abortus 2308
Sequence Strain (Species/Organism) Brucella melitensis biovar Abortus 2308
NCBI Gene ID 3788879
NCBI Protein GI 162002876
Locus Tag BAB1_0730
Protein Accession YP_414172.2
Other Database IDs UniProtKB-ID: Q2YN60_BRUA2
UniRef100: UniRef100_A9MA83
UniRef90: UniRef90_D0B2E0
UniRef50: UniRef50_B1ZKJ7
UniParc: UPI00000DD392
EMBL: AM040264
EMBL-CDS: CAJ10686.1
RefSeq_NT: NC_007618.1
GenomeReviews: AM040264_GR
KEGG: bmf:BAB1_0730
eggNOG: COG0299
HOGENOM: HBG649382
OMA: SFEARIH
ProtClustDB: PRK05647
BioCyc: BMEL359391:BAB1_0730-MONOMER
Taxonomy ID 359391
Chromosome No I
Gene Starting Position 713969
Gene Ending Position 714586
Gene Strand (Orientation) -
Protein Name phosphoribosylglycinamide formyltransferase
DNA Sequence 
>gi|82698932:713969-714586 Brucella melitensis biovar Abortus 2308 chromosome I, complete sequence
TTCAGGCGCTGAGCACCATGCCGTCCGAAAACTGGTTGGAAGCCTTCTCTCCAGCCGCAAACTTTTGAAG
CGCAAGCGGATAAAGCCGGTGTTCGGCCTTCAGCACGCGCGCGGCCAGCGTTTCGGCTGTATCGCCGTCC
AGCACCGGCACTGCGGCTTGTGCGAGGATTGGCCCTTCGTCCATGCCTTCCGTCACCAGATGGACGGTGC
AGCCCGCAAGCTTCATGCCCGCATCGAGCGCGCGCTGGTGCGTGTGCAGGCCCGGAAAAAGCGGTAGCAG
GGAAGGGTGGATATTAAGAATGCGCCCCTCGTAAGGGGCAATAAAGCGGCCTGACAGAAGGCGCATATAG
CCTGCAAGGCAGATAATATCCGGCTTGAGAACGTCGAGAGCGGCAAGGATCGCATCCTCATGCGCTTCTT
TGGAAGCAAAGTCCTTGCGCTTGAAAACCTGCGTGGCAATGCCTGCCGCTTCTGCCTTGGCAAGGCCGCC
CGCTTCTGCCTTGTCGGAAAAGACCGCTACGATTTCCGCCGGAAAACCGGGCGCTTGTGCCGCGCGGATC
AGCGCTTCCATGTTGGAGCCGCCGCCTGAAATAAAGATGACGACCCGGTTGCGTTTCA
Protein Sequence 
>gi|162002876|ref|YP_414172.2| phosphoribosylglycinamide formyltransferase [Brucella abortus 2308] MKRNRVVIFISGGGSNMEALIRAAQAPGFPAEIVAVFSDKAEAGGLAKAEAAGIATQVFKRKDFASKEAHEDAILAALDVLKPDIICLAGYMRLLSGRFIAPYEGRILNIHPSLLPLFPGLHTHQRALDAGMKLAGCTVHLVTEGMDEGPILAQAAVPVLDGDTAETLAARVLKAEHRLYPLALQKFAAGEKASNQFSDGMVLSA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: B. abortus purN gene is essential for intracellular growth in HeLa cells as shown from transposon mutagenesis study (Kim et al., 2003).
COG COG0299F, under F: Nucleotide transport and metabolism
References
Kim et al., 2003: Kim S, Watarai M, Kondo Y, Erdenebaatar J, Makino S, Shirahata T. Isolation and characterization of mini-Tn5Km2 insertion mutants of Brucella abortus deficient in internalization and intracellular growth in HeLa cells. Infection and immunity. 2003; 71(6); 3020-3027. [PubMed: 12761078].