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purF from Brucella melitensis biovar Abortus 2308

Victor ID 1735
Gene Name purF from Brucella melitensis biovar Abortus 2308
Sequence Strain (Species/Organism) Brucella melitensis biovar Abortus 2308
NCBI Gene ID 3788875
NCBI Protein GI 82699358
Locus Tag BAB1_0472
Protein Accession YP_413932.1
Other Database IDs UniProtKB-ID: Q2YMH7_BRUA2
UniRef100: UniRef100_D0B1Q7
UniRef90: UniRef90_D0B1Q7
UniRef50: UniRef50_B9JUS7
UniParc: UPI00000DD2D1
EMBL: AM040264
EMBL-CDS: CAJ10428.1
RefSeq_NT: NC_007618.1
MEROPS: C44.001
GenomeReviews: AM040264_GR
KEGG: bmf:BAB1_0472
eggNOG: COG0034
HOGENOM: HBG392416
OMA: GIPFELG
ProtClustDB: PRK09123
BioCyc: BMEL359391:BAB1_0472-MONOMER
Taxonomy ID 359391
Chromosome No I
Gene Starting Position 464197
Gene Ending Position 465654
Gene Strand (Orientation) -
Protein Name amidophosphoribosyltransferase
DNA Sequence 
>gi|82698932:464197-465654 Brucella melitensis biovar Abortus 2308 chromosome I, complete sequence
ATCAGCCGTTGCTGGCGAGCAGCGACAAGGTGTGGACGTTGCTTTCGCCTTCCTGATCCAGAAGGCGGGT
CGGATACTCGCCCGTGAAATAGTGATCGGTGAAGGTCGGCGCCTTTGGATCACGCGGCTTTCCGCCAACG
GCCTTGTAGAGCCCGTCGATGGAAAGGAAGGCCAGCGAATCGGCGCCGATGTAGCGGCACATGGATTCGA
GGCTTTCGTGCTGGTTGGCCAGCAGCTTATCGGCATGGGGGGTGTCGATACCGTAAAAATCCGGGTGGAA
GATCATCGGGCTTGCCACGCGCATATGGACTTCGGTTGCGCCTGCGTCGCGGATCATCTGAACGATCTTG
ACCGAGGTGGTGCCGCGCACGATGGAATCATCCACCAGAACGACCCGCTTGCCTTCAATCATAGCGCGAT
TGGCTGAATGTTTCAGCTTCACGCCAAGCGCGCGGATCTGCTGTGTAGGCTCAATGAAGGTGCGGCCCAC
ATAATGGTTGCGGATGATGCCATATTCAAACGGAATACCGCTTGCCTGCGCAAAGCCCAGCGCTGCCGGC
GTACCGCCATCCGGTACGGGCACGACCACATCGGCATCCACGCCCGCCTCGGCGGCAAGGTTCATGCCCA
TGTTCTTGCGCGCCACATAGACGCTGCGGCCACCCACTACCGAATCCGGCCGTGCGAAATAAACATATTC
AAAAAGGCACAGCCGCTCCGGCTGCGGATTTTCCGGCTTGATGGATCGGGTGGTGATGGAGCCATCCTTC
TGGATTTCGCAGACTACCACTTCGCCATTCTCGACGTCGCGAATATATTTCGCGCCGATAATATCGAGAG
CGCAGGTTTCCGAGCAGAAGATCGGCTTGCCGTCCAGCTCGCCCATGACGAGCGGGCGAATGCCGATGGG
ATCGCGCGCGGCGATCAGCTTGGTGCGGGTAAGCGCCAGCATGGCATAGCCGCCTTCAACCTGGCGGATC
GCTTCCACGAAACGGTCGGTTGAGGAGGAGTGCCGCGAACGGGCAATCATGTGCAGCACGACTTCCGTAT
CCGACGTTGCCTGGAAGATCGCGCCGGAAGCAATCAACTGTTTGCGCAGCGTAATGCCATTGGTGAAATT
GCCGTTATGGGCAATGGCGATGCCGCCGACTTCCAGTTCCGCAAACAGCGGCTGTACATTGCGCAGGATC
GTCTCGCCGGTTGTGGAATAACGCACATGGCCGATGGCGCGGTTGCCCGGCAGGCGGTTCAGTGTTGCCG
CATCGGTGAAATGGTCGCCGACGAGGCCCATATGGCGTTCGGAATGGAAACGGCGATTATGATAGGAAAC
AATGCCGGCGGCTTCCTGACCGCGATGCTGGAGCGCATGCAGGCCGAGCGCGGTCAGCGCAGCCGCATCC
TCATGGCCCAGAATGCCGAATACACCACATTCTTCATGCAGGGTGTCATCATCCAGCA
Protein Sequence 
>gi|82699358|ref|YP_413932.1| amidophosphoribosyltransferase [Brucella abortus 2308] MLDDDTLHEECGVFGILGHEDAAALTALGLHALQHRGQEAAGIVSYHNRRFHSERHMGLVGDHFTDAATLNRLPGNRAIGHVRYSTTGETILRNVQPLFAELEVGGIAIAHNGNFTNGITLRKQLIASGAIFQATSDTEVVLHMIARSRHSSSTDRFVEAIRQVEGGYAMLALTRTKLIAARDPIGIRPLVMGELDGKPIFCSETCALDIIGAKYIRDVENGEVVVCEIQKDGSITTRSIKPENPQPERLCLFEYVYFARPDSVVGGRSVYVARKNMGMNLAAEAGVDADVVVPVPDGGTPAALGFAQASGIPFEYGIIRNHYVGRTFIEPTQQIRALGVKLKHSANRAMIEGKRVVLVDDSIVRGTTSVKIVQMIRDAGATEVHMRVASPMIFHPDFYGIDTPHADKLLANQHESLESMCRYIGADSLAFLSIDGLYKAVGGKPRDPKAPTFTDHYFTGEYPTRLLDQEGESNVHTLSLLASNG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A B. suis purF mutation experiment suggests that the purine biosynthesis pathway contributes to intracellular growth (Kim et al., 2003).
COG COG0034F, under F: Nucleotide transport and metabolism
References
Kim et al., 2003: Kim S, Watarai M, Kondo Y, Erdenebaatar J, Makino S, Shirahata T. Isolation and characterization of mini-Tn5Km2 insertion mutants of Brucella abortus deficient in internalization and intracellular growth in HeLa cells. Infection and immunity. 2003; 71(6); 3020-3027. [PubMed: 12761078].