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gmd from Brucella melitensis biovar Abortus 2308

Victor ID 1717
Gene Name gmd from Brucella melitensis biovar Abortus 2308
Sequence Strain (Species/Organism) Brucella melitensis biovar Abortus 2308
NCBI Gene ID 3788735
NCBI Protein GI 82699425
Locus Tag BAB1_0545
Protein Accession YP_413999.1
Other Database IDs UniProtKB-ID: Q2YMP3_BRUA2
UniRef100: UniRef100_D0B1X8
UniRef90: UniRef90_D0B1X8
UniRef50: UniRef50_O60547
UniParc: UPI000005806B
EMBL: AM040264
EMBL-CDS: CAJ10501.1
RefSeq_NT: NC_007618.1
GenomeReviews: AM040264_GR
KEGG: bmf:BAB1_0545
eggNOG: COG1089
HOGENOM: HBG755066
OMA: TQRVDHI
ProtClustDB: CLSK864399
BioCyc: BMEL359391:BAB1_0545-MONOMER
Taxonomy ID 359391
Chromosome No I
Gene Starting Position 538823
Gene Ending Position 539911
Gene Strand (Orientation) -
Protein Name Short-chain dehydrogenase/reductase SDR:GDP-mannose 4,6-dehydratase
DNA Sequence 
>gi|82698932:538823-539911 Brucella melitensis biovar Abortus 2308 chromosome I, complete sequence
ATCATTCCTTAGGGGCGAAAAATTGGTGACCATGTTCGCGCAGCAAATTCTCACGAGCCGCCGCCGCTAA
GTCTTCTGCTATCATCTCAGATACAAGCGTCTCAAAAGAGATTTTGGGCTTCCAGCCCAGTTTTTGATGC
GCCTTGGTCGCATCTCCCAGAAGAGTTTCCACCTCGGCTGGTCGAAAGTATCTAGGATCGACCTCGACAA
TACATGCACCGGTCTTGGCATCATAACCCTTCTCGGCTTCACCGCTACCTTCCCATCGCATCTCAATGCC
TATGTCTTTAGCAGCGAGCGTGACAAATTCTCGAACTGAATATTGTTTACCAGTTGCTATTACAAAATCT
TCTGGTTGATCCTGTTGAAGCATTAACCACTGCATCTCGACGTAGTCCCGAGCATGCCCCCAGTCGCGTA
ATGAGTCCAAATTCCCTAAGTATAAGCGATTCTGATTACCGATCTTAATTCTAGCTAAAGCGCGAGTAAT
TTTTCTCGTGACAAAAGTCTCTCCTCTAAGTGGAGATTCATGGTTAAAAAGTATGCCATTACAAGCATAT
ATACCATACGCCTCTCGGTAGTTTACCGTAATCCAATAGGCATAAAGCTTCGCTGCGGCATAGGGCGACC
GAGGGTAAAAAGGCGTCGTTTCTTTTTGCGGGATTTCTTGAACCAGACCATAAAGCTCAGAGGTGGATGC
TTGGTAGTACCGGGTCTGCTTCTCCATTCCAAGAATTCGGATCGCCTCTAGCAGACGAAGGGCACCTAGT
GCGTCTGAGTTCGCAGTATACTCCGGCTCCTCAAATGAAACAGCAACATGGCTTTGTGCGCCAAGGTTAT
AAACTTCATCCGGCCGAACGAGCTGCATGATTCGAACCAAGCTTGACGTATCTGTTAGATCGCCATGATG
AAGTGTTAGATCGACACCCTGCTCGTGCGGATCATGGTACAGATGATCGATACGTGCTGTGTTAAATTGC
GAGGTGCGACGCTTAATCCCGTGTACTGCATAACCTTTTTGTAGAAGCAATTCCGCAAGGTAGGCGCCGT
CTTGGCCGGTGATACCTGTGATAAGTGCGACTTTCTTCA
Protein Sequence 
>gi|82699425|ref|YP_413999.1| short-chain dehydrogenase [Brucella abortus 2308] MKKVALITGITGQDGAYLAELLLQKGYAVHGIKRRTSQFNTARIDHLYHDPHEQGVDLTLHHGDLTDTSSLVRIMQLVRPDEVYNLGAQSHVAVSFEEPEYTANSDALGALRLLEAIRILGMEKQTRYYQASTSELYGLVQEIPQKETTPFYPRSPYAAAKLYAYWITVNYREAYGIYACNGILFNHESPLRGETFVTRKITRALARIKIGNQNRLYLGNLDSLRDWGHARDYVEMQWLMLQQDQPEDFVIATGKQYSVREFVTLAAKDIGIEMRWEGSGEAEKGYDAKTGACIVEVDPRYFRPAEVETLLGDATKAHQKLGWKPKISFETLVSEMIAEDLAAAARENLLREHGHQFFAPKE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: gmd may be involved in perosamine synthesis. It has been shown to be in LPS synthesis since its B. melitensis mutation induces rough phenotype (Moriyón et al., 2004).
COG COG1089M, under M: Cell wall/membrane/envelope biogenesis
References
Moriyón et al., 2004: Moriyón I, Grilló MJ, Monreal D, González D, Marín C, López-Goñi I, Mainar-Jaime RC, Moreno E, Blasco JM. Rough vaccines in animal brucellosis: structural and genetic basis and present status. Veterinary research. 2004; 35(1); 1-38. [PubMed: 15099501].