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glnA from Brucella melitensis biovar Abortus 2308

Victor ID 1714
Gene Name glnA from Brucella melitensis biovar Abortus 2308
Sequence Strain (Species/Organism) Brucella melitensis biovar Abortus 2308
NCBI Gene ID 3788725
NCBI Protein GI 82699855
Locus Tag BAB1_1023
Protein Accession YP_414429.1
Other Database IDs UniProtKB-ID: Q2YQ67_BRUA2
UniRef100: UniRef100_B2S5L6
UniRef90: UniRef90_A9MB20
UniRef50: UniRef50_P00964
UniParc: UPI00004F902A
EMBL: AM040264
EMBL-CDS: CAJ10979.1
RefSeq_NT: NC_007618.1
GenomeReviews: AM040264_GR
KEGG: bmf:BAB1_1023
eggNOG: COG0174
HOGENOM: HBG553755
OMA: FAEGTMF
ProtClustDB: CLSK862961
BioCyc: BMEL359391:BAB1_1023-MONOMER
Taxonomy ID 359391
Chromosome No I
Gene Starting Position 983239
Gene Ending Position 984648
Gene Strand (Orientation) -
Protein Name Glutamine synthetase class-I, adenylation site:Glutamine synthetase type I:Glutamine synthetase, catalytic domain:Glutamine s...
DNA Sequence 
>gi|82698932:983239-984648 Brucella melitensis biovar Abortus 2308 chromosome I, complete sequence
TTTATACCGAGTAATACATATCGAACTCGACCGGGTGCGGCGTCATTTCAAAACGCATCACTTCAGCCAT
TTTCAGCTCGATGAAGCTGTCGATCTGGTCGTCGGAGAACACGCCGCCAGCCTTGAGGAATTCACGATCC
TTGTTGAGCGACTGTAGAGCTTCACGCAGGGAGCCGCAGACGGTCGGAATCTGCTTCAGTTCCTTCGGCG
GCAGGTCGTAGAGATCCTTGTCCATGGCCTGGCCCGGATGGATCTTGTTCTTGATGCCGTCAAGGCCCGC
CATCAGAAGGGCCGAGAAGCAGAGATAAGGGTTGGCGGACGGATCCGGGAAGCGGACTTCGAGACGCTTC
GATTTCGGCGAGGAGCCGAATGGAATGCGGCAGGAAGCCGAACGGTTGCGTGCGGAATAGGCCAGCAGAA
CAGGCGCTTCATAGCCCGGCACCAGACGCTTGTAGGAGTTGGTGGACGGGTTGGTGAAGGCATTCACAGC
TTTTGCGTGCTTGATGACGCCGCCAATGAAGTAGAGGCAGTTTTCCGACAGACCAGCATATTCATTGCCT
GCGAAGGTCGGCTTGCCGTCTTTCCAGATCGAGAAGTGAACATGCATGCCGGAGCCATTGTCGCCAAAGA
CCGGCTTCGGCATGAAGGTTGCCGTTTTGCCATAGGCATTGGCAACCTGATGCACGACATATTTCTGAAT
CTGCATCTTGTCGGCGTTGCGCACCAGCGTGTCGAATTTCGTGCCCAGTTCGTGCTGCGCGGAAGCGACT
TCATGGTGGTGCTTTTCAACCGTCACACCCATTTCCGAGAGCACGGTCAGCATTTCGGAACGCATGTCCT
GCAAGCTGTCGATTGGCGGAACGGGGAAATAGCCGCCCTTGACGCGCGGACGATGGCCGAGATTGCCGGT
TTCATAATCGGTGTCGTCGTTGGATGGCAATTCGGCGCTATCGAGCTTGAAGCCCGTATTGAACGGATCG
GCCTTGAACTTCACATCGTCGAAGACGAAGAATTCGGCTTCCGGGCCGACATAGACCGTATCGCCAATGC
CGAGCGATTTCAGATAGGCTTCGGCCTTCTTGGCAGTCGTACGCGGATCACGGCTGTAGCTTTCGCCGGA
AAGCGGCTCAAGGATATCGCAGAGAATGACAAGCGTGGACTGGGCGAAGAACGGGTCGATATGAGCCGTT
TCCGGATCGGGCATCAAAACCATGTCGGATTCGTTGATGGCCTTCCAGCCTGCGATCGAAGAGCCGTCGA
ACATGACACCGTCGACGAACATGTCTTCGTCCACGAGGCCGATATCCATCGTAACGTGATGGAGCTTGCC
CTTCGGATCGGTGAAGCGAAGGTCGACGAACTTGACGTCGTTATCTTTGATCTGTTTCAGAATATCGTTG
GCAGTCGTCA
Protein Sequence 
>gi|82699855|ref|YP_414429.1| glutamine synthetase [Brucella abortus 2308] MTTANDILKQIKDNDVKFVDLRFTDPKGKLHHVTMDIGLVDEDMFVDGVMFDGSSIAGWKAINESDMVLMPDPETAHIDPFFAQSTLVILCDILEPLSGESYSRDPRTTAKKAEAYLKSLGIGDTVYVGPEAEFFVFDDVKFKADPFNTGFKLDSAELPSNDDTDYETGNLGHRPRVKGGYFPVPPIDSLQDMRSEMLTVLSEMGVTVEKHHHEVASAQHELGTKFDTLVRNADKMQIQKYVVHQVANAYGKTATFMPKPVFGDNGSGMHVHFSIWKDGKPTFAGNEYAGLSENCLYFIGGVIKHAKAVNAFTNPSTNSYKRLVPGYEAPVLLAYSARNRSASCRIPFGSSPKSKRLEVRFPDPSANPYLCFSALLMAGLDGIKNKIHPGQAMDKDLYDLPPKELKQIPTVCGSLREALQSLNKDREFLKAGGVFSDDQIDSFIELKMAEVMRFEMTPHPVEFDMYYSV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A study with miniTn5 mutants of B. suis constitutively expressing gfp indicates that B. suis glnA gene is required for intracellular multiplication in human macrophage THP-1 cells (Kohler et al., 2002).
COG COG0174E, under E: Amino acid transport and metabolism
References
Kohler et al., 2002: Kohler S, Foulongne V, Ouahrani-Bettache S, Bourg G, Teyssier J, Ramuz M, Liautard JP. The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell. Proceedings of the National Academy of Sciences of the United States of America. 2002 Nov 26; 99(24); 15711-6. [PubMed: 12438693 ].