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Rv3881c

Victor ID 171
Gene Name Rv3881c
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886214
NCBI Protein GI 15611017
Locus Tag Rv3881c
Protein Accession NP_218398.1
Other Database IDs UniProtKB-ID: ESPB_MYCTU
UniRef100: UniRef100_Q933K8
UniRef90: UniRef90_Q933K8
UniRef50: UniRef50_B2HNQ9
UniParc: UPI000012ECFF
EMBL: AY029285
EMBL: BX842584
EMBL: AE000516
EMBL-CDS: AAK31576.1
EMBL-CDS: CAA17973.1
EMBL-CDS: AAK48364.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000002868
EnsemblGenome_TRS: EBMYCT00000002870
EnsemblGenome_PRO: EBMYCP00000002870
EnsemblGenome: EBMYCG00000071066
EnsemblGenome_TRS: EBMYCT00000071071
EnsemblGenome_PRO: EBMYCP00000069130
Geno
Taxonomy ID 83332
Gene Starting Position 4360542
Gene Ending Position 4361924
Gene Strand (Orientation) -
Protein Name CONSERVED HYPOTHETICAL ALANINE AND GLYCINE RICH PROTEIN
DNA Sequence 
>gi|57116681:4360542-4361924 Mycobacterium tuberculosis H37Rv, complete genome
CTCACTTCGACTCCTTACTGTCCTGGCGCCGACGGTTACCAATGACGGCCTCGGTCCATGCCCGATCCTC
GGTGTAGAGCGCCTCGTCTTCCTGCTGAGAACCCTTGGACTTGGCGCCCCCTTGTCCCTGATGCGCGGCA
CCCATCGGCATTCCCATGCCACCGCCGCCCAGCGCGGCGCCGCCGCCGGCCCTTCCCTGGCCTAAGCCGG
CAATGTCACCAGCGCCAGCGGGCCGCACCGATTCGGCGCCCCCGATCGCGGATCCCAACGGCGCCGACGG
CACCCCGCCGCCTCCACCGCCACCGAGCGATGCCGCTTTGACCGCCACGTCGCCCGACAGCGCTGCGGCT
TCCCGCCCAGCCGACGTCAGCTGCGCCGCCGTGTCAGCCGGGAGGCCACCACCCGGCGATCCGGTAGGCG
GAACCATCGGTGCGGCTGGCATCCCGGTACCGGGAGTCACACCGGAGCCGTCAGACGGCGGCATCAGGAA
GCCAGGGATCAATCCCTGCTCTTGCGGAGGCGGGGGCGGGTCGATCTTGATGGCGGGGGGAGGCTTCGGC
GGGTTTACCGGTTCCAGGGCTGCCTTGTTGTTGTATTCGGTCAGCACCTTCTCCGACCTCTGCTGATACT
CCGCGTACACCGGGAGAATTTGGTCGCGGGCCGAAGGGTTTTCCGCGTAAAGCCGTTCGAGCCCGACTAT
GTCTTCATAAGTCGGATGTTCCCGCCTAGCCCACACGTGCAGCTGCGCGACATATTGAGCCTGCTTGGCC
ATCGCAGCGCTCAATTTGGCCATGTGGAGTATCCATTGCCGTTGTTGATCGAGCGAAGCCTCGCAAGCGG
TAGCCGCATCGCCTTCCCAGTTGTCAAACCCCCGGAACCGCTTGACGTCGCCTTGCAGCGTCAGGTTGAA
AGTGTTCCACCCATCCGCAAAGTGCGCGAGCGATGCGCCTTGGTCGCCCGTTTCGAGCTTCCTTGCCGCT
TCTTTGAGATCCATGAAGTTGGGTTCACCGGCCGTGGCCACCCTCGGCGTATCGGTTAGTTCGGCCGAAC
TGTCCCCTCCGACGGCCCCGGCCGATTCTGCCTGCACAGTTCCTTCGCCGTCGTTGTCCAGCGCGGTCGC
AGCCTCCTCATCAACCTCGCCATACGCCTTGGCCGCGTTGCGCAGCGAGGTCGCCAGACGCTGCCGCTCT
TTGGCACCGGCCGCCAGGTATTCCCGCATGTTGTCGGCGGACAATACCAGCTGTTGGGCGGCGTTTTTAG
CCGCCGTGAGTTCGCACGGTGTGATGGGGACATCAGTCGGTGGGTCCGCCATCGGGGCCTCCACCTCGTT
GGCCCTGTTCAAAATCTCTTGCTGATCCACCGTCACGGTCTGCGACTGCGTCA
Protein Sequence 
>gi|15611017|ref|NP_218398.1| ESX-1 secretion-associated protein EspB [Mycobacterium tuberculosis H37Rv] MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKAYGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFNLTLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENPSARDQILPVYAEYQQRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQGQGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Rv3881c (espB) mutant is attenuated in macrophages (McLaughlin et al., 2007).
References
McLaughlin et al., 2007: McLaughlin B, Chon JS, MacGurn JA, Carlsson F, Cheng TL, Cox JS, Brown EJ. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS pathogens. 2007; 3(8); e105. [PubMed: 17676952].