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cadF

Victor ID 1700
Gene Name cadF
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni 81-176
NCBI Gene ID 4683585
NCBI Protein GI 121612147
Locus Tag CJJ81176_1471
Genbank Accession NZ_AASL01000001
Protein Accession YP_001001127
Other Database IDs UniProtKB-ID: A1W186_CAMJJ
UniRef100: UniRef100_A1W186
UniRef90: UniRef90_A1W186
UniRef50: UniRef50_B9KFA9
UniParc: UPI0000698E47
EMBL: CP000538
EMBL-CDS: EAQ72738.1
RefSeq_NT: NC_008787.1
GenomeReviews: CP000538_GR
KEGG: cjj:CJJ81176_1471
TIGR: CJJ81176_1471
eggNOG: COG2885
HOGENOM: HBG730341
OMA: DENGCEK
ProtClustDB: CLSK879280
BioCyc: CJEJ354242:CJJ81176_1471-MONOMER
Taxonomy ID 354242
Gene Starting Position 1392005
Gene Ending Position 1392964
Gene Strand (Orientation) -
Protein Name fibronectin-binding protein
Protein pI 6.19
Protein Weight 34598.8
Protein Length 319
Protein Note identified by match to protein family HMM PF00691; match to protein family HMM PF01389
DNA Sequence 
>gi|121612099:1392005-1392964 Campylobacter jejuni subsp. jejuni 81-176, complete genome
ATTATCTTAAAATAAATTTAGCATCCACTCTTCTATTATCCGCTCTACCTTCTTTAGTGTCATTGCTTGA
GCGAGGATTATCTTGTCCATAACCTACTGTTTTGATGCGACTTTTTTCTACACCATATTTTTCAAGTTCA
TTAGCAACACTTTTAGCACGTCTTTCTGAAAGCTTTTGATTATAAGCTCTTGAACCTATATTATCTGTAT
GTCCTTCAAGAATAGTATCATATCTTTCATTTTCATCTAAAACTTTTGCAATTTCTTTGATTTTTTCTTG
AAAAGTTGGATTTATAGTAGTTTTATCAAAACCAAAATGACCTTCCAAAGAAATAGTTTTTTCGCAACCA
TTTTCATCTAACAAAGCACCTTCTCTTGGTTCTACAGGACATTTTGCTTGTGGAGCTGGACGAGTATCAG
CAACTTCTTCTACAGCTTTTTCCTTTTTGCCACCAAAACCAAAACTAATACCTAAAGTTGAAACCCAATT
ATGGTTTGCATGATTAAAATTAATTTGATCTCTAGTTTCAAGTCTTAAAGCCAAAGAATCACTAAGGCGG
AATTTTACACCCGCGCCATAATGTCCAAATCCACCGCTTTTATTATCATAAGCAGCATTTGAAAAATCCT
CATATCCTCCACCTGCTAAACCATAGAAATAAAATTTCTCACCTACATCAATACCTTTAATAGCACTCAA
ATAAGTTCTTGTAATATCTGTAGTTTTATTTGTATTTGTATATTTAACATCAGAATAATGCTCTAACCCA
AATTCTAATTGATCAAGCCAAAAATCGTCAAAATGATAACCAAGTCTAATCCCTGGTGCATAACGATTAT
CCATATCTAAATTACCTTCAAAGTAATTATAGTTTAAAGTTGGAGTGATTTCAAATTTTACATTGTTATC
AGCACTGAATAAAACACTTGCCAAACCTAAACATAATAATATTTTTTTCA
Protein Sequence 
>gi|121612147|ref|YP_001001127.1| fibronectin-binding protein [Campylobacter jejuni subsp. jejuni 81-176]
MKKILLCLGLASVLFSADNNVKFEITPTLNYNYFEGNLDMDNRYAPGIRLGYHFDDFWLDQLEFGLEHYS
DVKYTNTNKTTDITRTYLSAIKGIDVGEKFYFYGLAGGGYEDFSNAAYDNKSGGFGHYGAGVKFRLSDSL
ALRLETRDQINFNHANHNWVSTLGISFGFGGKKEKAVEEVADTRPAPQAKCPVEPREGALLDENGCEKTI
SLEGHFGFDKTTINPTFQEKIKEIAKVLDENERYDTILEGHTDNIGSRAYNQKLSERRAKSVANELEKYG
VEKSRIKTVGYGQDNPRSSNDTKEGRADNRRVDAKFILR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cadF mutants had reduced binding to immobilized Fn as compared to wt strains (Monteville et al., 2003)
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Monteville et al., 2003: Monteville MR, Yoon JE, Konkel ME. Maximal adherence and invasion of INT 407 cells by Campylobacter jejuni requires the CadF outer-membrane protein and microfilament reorganization. Microbiology (Reading, England). 2003; 149(Pt 1); 153-165. [PubMed: 12576589].