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Rv3887c

Victor ID 170
Gene Name Rv3887c
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886211
NCBI Protein GI 15611023
Locus Tag Rv3887c
Protein Accession NP_218404.1
Other Database IDs UniProtKB-ID: ECCD2_MYCTU
UniRef100: UniRef100_O05457
UniRef90: UniRef90_O05457
UniRef50: UniRef50_O05457
UniParc: UPI00000C1517
EMBL: BX842584
EMBL: AE000516
EMBL-CDS: CAB08087.1
EMBL-CDS: AAK48369.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000002019
EnsemblGenome_TRS: EBMYCT00000002021
EnsemblGenome_PRO: EBMYCP00000002021
GenomeReviews: AE000516_GR
GenomeReviews: AL123456_GR
KEGG: mtu:Rv3887c
TIGR: MT4002
TubercuList: Rv3887c
HOGENOM: HBG564734
OMA: EVLAFIV
ProtClus
Taxonomy ID 83332
Gene Starting Position 4370154
Gene Ending Position 4371683
Gene Strand (Orientation) -
Protein Name PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
DNA Sequence 
>gi|57116681:4370154-4371683 Mycobacterium tuberculosis H37Rv, complete genome
TTTAGTGGCGAAGCCATGCAAACAGCCCCCCTAGGGCCGCAGCCGCTGGTAACAACGCGATCATGGCCAG
CACTTCTAGCCATTCCACGGTCAACCGGATGATCGGCCTAAACCGCGTCGCCGGTACCACGAGGGCCACG
GCCAAACCCAATGCGGCGAAAGCCGCGACGAAGATCGCAGGCCAAAGCAGCCCGGTCTGAACACCTTTCG
GGGTGTCGAGGGCGTACTTAAGCACCCCGGCACACACCGCGGCGGACGCCCCGCACACCAATGCGACCGC
TTGGTATTTGGCGGCGAACCCGCGGCCCTGGGTGATGAAGAGGCCCACCGTCAAGCCGGCAACCAACAAC
GCCAACCAGGCCCACGGTTGACGTGGCGTCAGCACCCCCCATACCGCGGCGGGCAGTACGAGCGACACCC
CGACGCACATACCCACCTGTACCGCGTTAACCAGCCGCGCCGACGCGGCGATCGCGGTGCCGCGGGCGGT
GATGTCGGTCAGTTCATTGTCCTCATCGTCGGCGTCGGCTTCGCTGACCGGAGCCACCGTATCGACGGGC
ATTCCCGCACGGCGCGCGAACAGATCCCGGCCGGTGATCGATCCGAAGTGCGGGGGTCGTACCCGTGCCA
CCCACAACGCAACGGTCGGAGTCATCCTGATCAGGACAAGCAGCCCTACCAGCACGCAAATCGCCAGCAC
CTGCATCGAAACCGGCCTAAACATTCGGACGGCGGCGACAGCGGCAAGGATCCCGCACACCGTTACCACC
GCGGTGACCACTGCGGTCTGCCACCGCTTGCGGGTCGCCACGCCGATCGTGATCGCACCCAGAACCACCA
CCACGAGCCCGATCAGCGCATGAGCCGCCCCGAGCGCGCCCGGCGGCGCGCACGCGGCGGCCACGGCAAG
CAACACCACCGCCAGCCACCCGAACCCACTGAACAGGTCACGGCGCTCCCGCCAACCCCACCACACCACC
AATGCCCCGATCACCAGGAGCACACCAATCCCGCCAGCCATCGCAGCTGGGACCGGGCTGTCGGTGATTG
TGCGTGTCCGCAACGTCAGGGCCAGCACCACTCCGACCGCCATGGCGATAATCGCCATGGCGGTGTGGGC
GGCAGTCAGCGAGGTTACCGGCGCAAACATCCGATCCCCGCCGTCACGCCCCAGCCACTTGCCCATGGCC
GCCAGCCCGGTGGATAGCGATTCGTACTGTGGCTCAAACGACTCGCCAGCAACCCGGGGTACTAGCACCA
GCGTGTCACCGTCTTGAACGCCCAGCTCGTCGAGGCTCTTGTTGATGTCCAGCCGCACCCCGTTGATCTT
GTGTAGCTCATAGCTACCCGCCGGCAGCGCAACCCCGTCGAAACCTTTGCGCTTCAGATCGGCATCGAAC
AACTCCACCATTCCTTCGAAGAATCCCTCTACTGGAATTCCGGCGGGGAATACCTGGGAGCATAGATGCT
TGTCGTAGCAAATGTTGACCGCACAACGTGCCGGGAAAGCAACCTTATGCGGCGCAGTCA
Protein Sequence 
>gi|15611023|ref|NP_218404.1| ESX-2 secretion system protein EccD [Mycobacterium tuberculosis H37Rv] MTAPHKVAFPARCAVNICYDKHLCSQVFPAGIPVEGFFEGMVELFDADLKRKGFDGVALPAGSYELHKINGVRLDINKSLDELGVQDGDTLVLVPRVAGESFEPQYESLSTGLAAMGKWLGRDGGDRMFAPVTSLTAAHTAMAIIAMAVGVVLALTLRTRTITDSPVPAAMAGGIGVLLVIGALVVWWGWRERRDLFSGFGWLAVVLLAVAAACAPPGALGAAHALIGLVVVVLGAITIGVATRKRWQTAVVTAVVTVCGILAAVAAVRMFRPVSMQVLAICVLVGLLVLIRMTPTVALWVARVRPPHFGSITGRDLFARRAGMPVDTVAPVSEADADDEDNELTDITARGTAIAASARLVNAVQVGMCVGVSLVLPAAVWGVLTPRQPWAWLALLVAGLTVGLFITQGRGFAAKYQAVALVCGASAAVCAGVLKYALDTPKGVQTGLLWPAIFVAAFAALGLAVALVVPATRFRPIIRLTVEWLEVLAMIALLPAAAALGGLFAWLRH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Rv3887c mutant is attenuated in mice (MacGurn and Cox, 2007).
References
MacGurn and Cox, 2007: MacGurn JA, Cox JS. A genetic screen for Mycobacterium tuberculosis mutants defective for phagosome maturation arrest identifies components of the ESX-1 secretion system. Infection and immunity. 2007; 75(6); 2668-2678. [PubMed: 17353284].