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esxA from Mycobacterium tuberculosis H37Rv

Victor ID 169
Gene Name esxA from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886209
NCBI Protein GI 57117165
Locus Tag Rv3875
Protein Accession YP_178023.1
Other Database IDs UniProtKB-ID: ESXA_MYCTU
UniRef100: UniRef100_P0A565
UniRef90: UniRef90_P0A565
UniRef50: UniRef50_P0A565
UniParc: UPI0000036DD3
EMBL: X79562
EMBL: AF420491
EMBL: BX842584
EMBL: AE000516
EMBL: AF004671
EMBL-CDS: CAA56099.1
EMBL-CDS: AAL16896.1
EMBL-CDS: CAE55648.1
EMBL-CDS: AAK48357.1
EMBL-CDS: AAC83446.1
RefSeq_NT: NC_002755.2
RefSeq_NT: NC_000962.2
PDB: 1WA8
PDB: 3FAV
TCDB: 1.C.95.1.1
EnsemblGenome: EBMYCG00000000085
EnsemblGenome_TRS: EBMYCT00000000085
EnsemblGenome_PRO: EBMYCP00000000085
Ense
Taxonomy ID 83332
Gene Starting Position 4352608
Gene Ending Position 4352895
Gene Strand (Orientation) +
Protein Name 6 KDA EARLY SECRETORY ANTIGENIC TARGET ESXA (ESAT-6)
DNA Sequence 
>gi|57116681:4352608-4352895 Mycobacterium tuberculosis H37Rv, complete genome
CATGACAGAGCAGCAGTGGAATTTCGCGGGTATCGAGGCCGCGGCAAGCGCAATCCAGGGAAATGTCACG
TCCATTCATTCCCTCCTTGACGAGGGGAAGCAGTCCCTGACCAAGCTCGCAGCGGCCTGGGGCGGTAGCG
GTTCGGAGGCGTACCAGGGTGTCCAGCAAAAATGGGACGCCACGGCTACCGAGCTGAACAACGCGCTGCA
GAACCTGGCGCGGACGATCAGCGAAGCCGGTCAGGCAATGGCTTCGACCGAAGGCAACGTCACTGGGATG
TTCGCATA
Protein Sequence 
>gi|57117165|ref|YP_178023.1| ESAT-6 protein EsxA [Mycobacterium tuberculosis H37Rv] MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMFA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: esxA (ESAT-6) mutant is attenuated in mice (Fortune et al., 2005).
COG COG4842S, under S: Function unknown
References
Fortune et al., 2005: Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ. Mutually dependent secretion of proteins required for mycobacterial virulence. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(30); 10676-10681. [PubMed: 16030141].