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ipgD from Shigella boydii CDC 3083-94

Victor ID 1679
Gene Name ipgD from Shigella boydii CDC 3083-94
Sequence Strain (Species/Organism) Shigella boydii CDC 3083-94
NCBI Gene ID 6273427
NCBI Protein GI 187734497
Locus Tag SbBS512_A0166
Protein Accession YP_001883195.1
Other Database IDs UniProtKB-ID: B2TSY3_SHIB3
UniRef100: UniRef100_Q933B2
UniRef90: UniRef90_Q07566
UniRef50: UniRef50_Q07566
UniParc: UPI00000AFB27
EMBL: CP001062
EMBL-CDS: ACD06268.1
RefSeq_NT: NC_010660.1
EnsemblGenome: EBESCG00000074861.
EnsemblGenome_TRS: EBESCT00000075814
EnsemblGenome_PRO: EBESCP00000072963
GenomeReviews: CP001062_GR
KEGG: sbc:SbBS512_A0166
HOGENOM: HBG671713
OMA: NSSERAV
ProtClustDB: CLSK862850
Taxonomy ID 344609
Plasmid No pBS512_211
Gene Starting Position 111635
Gene Ending Position 113251
Gene Strand (Orientation) +
Protein Name inositol phosphate phosphatase IpgD
DNA Sequence 
>gi|187734273:111635-113251 Shigella boydii CDC 3083-94 plasmid pBS512_211, complete sequence
AATGCACATAACTAATTTGGGATTGCATCAGGTTTCATTTCAAAGCGGAGATTCCTATAAAGGCGCAGAA
GAAACCGGAAACCAAAAAGGTGTAAGCGTGATTTCATATCAAAGAGTTAAAAATGGAGAGAGAAATAAGG
GGGTCGAAGCGCTTAATCGATTATATTTACAGAACCAAACAAGCTTAACAGGGAAAGGCCTTTTGTTTGC
GCGTGACAGAGCTGCAGTTTTTTACGAGGCAATAAAGTTGGCAGGTGGTGATACGTCAAAAATTAAAGCC
ATGATGGAACAATTAGATACCTATAAACTTGGTGAAGTTGATAAAAGAAATATTAATGAGCTTAATAAAG
TAATAAGTGAAGAGATAGGAGCACAGCTAGGCATTAAAAATAAAAAGGAATTGCAATCGGAAATAAAACA
AATATTTACTAATTATTTAAATAATAAGAATTGGGAACCGATCAACAAAAATATTAATTATCATGGGAAA
AATTATGGTTTTCAATTAACACCCGCCTCTCATATGAAGATAGGGAATAAAAATATATTTGTCAAAGAGT
ATAATGGAAAAGGAATTTGTTGTGCTTCTACGAGAGAGAGTGAGCATATTGCGAATATGTGGCTTTCAAA
AGTGGTGGATGACGAGGGGAAGGAAATTTTTTCGGGTATCAGACATGGAGTTATATCAGCCTATGGATTG
AAAAAAAACTCATCTGAAAGAGCTGTTGCAGCTCGTAATAAAGCTGAGGAGTTAGCAAGCGCAGCATTAT
ATAGCAGACAAGAATTATTATCACAGGCTTTGTCTGGTAAAACAGTAGATTTAAAGATTGTTTCGACTTC
TCTTCTGACGCCGACCAGTTTAACTGGGGGAGAGGAGAGTATGTTAAAAGATCAGGTAAAGGCATTAAAA
GGGTTAAACTCTAAAAGGGGGGAACCAACGAAATTATTAATTCGGAATAGTGATGGTCTTCTGCAAGAAG
TAAAGGTTAATCTAAAAGTGGTGACATTTAACTTTGGTGTAAATGAATTAGCGCTAAAAATGGGCTTAGG
CTGGAGGAATGTTGACAAGCTTAATGGTGAATCAATATGTTCTTTGTTGGGGGATAATTTCCTCAAAAAT
GGTGTGATTGGAGGTTGGGCTGCAGAAGCTATAGAAAAAAATCCACCATGTAAGAATGATGTGATATATC
TGGCTAACCAGATAAAAGAGATTGTAAACAAGAAGTTACAAAAAAATGATAATGGAGAGCCGTATAAATT
GTCACAAAGAATGGCTCTATTGGCTTATACTATAGGTGCTGTACCTTGCTGGAATTGTAAGAGTGGGAAG
GACAGAACAGGTATGCAGGATGCTGAAATTAAAAGAGAAATAATAAGAAAACATGAAACAGGGCAGTTTT
CTCAATTAAATAGTAAATTATCCTCAGAAGAGAAAAGATTATTTTCTACTATTCTAATGAATAGTGGTAA
TATGGAAATCCAAGAGATGAATACTGGTGTGCCTGGAAATAAAGTTATGAAAAAATTACCGCTATCTTCG
TTAGAGCTGTCTTATGCTGAAAGAATAGGGGACCCCAAAATATGGAATATGGTGAAAGGGTATTCGTCAT
TTGTATA
Protein Sequence 
>gi|187734497|ref|YP_001883195.1| inositol phosphate phosphatase IpgD [Shigella boydii CDC 3083-94] MHITNLGLHQVSFQSGDSYKGAEETGNQKGVSVISYQRVKNGERNKGVEALNRLYLQNQTSLTGKGLLFARDRAAVFYEAIKLAGGDTSKIKAMMEQLDTYKLGEVDKRNINELNKVISEEIGAQLGIKNKKELQSEIKQIFTNYLNNKNWEPINKNINYHGKNYGFQLTPASHMKIGNKNIFVKEYNGKGICCASTRESEHIANMWLSKVVDDEGKEIFSGIRHGVISAYGLKKNSSERAVAARNKAEELASAALYSRQELLSQALSGKTVDLKIVSTSLLTPTSLTGGEESMLKDQVKALKGLNSKRGEPTKLLIRNSDGLLQEVKVNLKVVTFNFGVNELALKMGLGWRNVDKLNGESICSLLGDNFLKNGVIGGWAAEAIEKNPPCKNDVIYLANQIKEIVNKKLQKNDNGEPYKLSQRMALLAYTIGAVPCWNCKSGKDRTGMQDAEIKREIIRKHETGQFSQLNSKLSSEEKRLFSTILMNSGNMEIQEMNTGVPGNKVMKKLPLSSLELSYAERIGDPKIWNMVKGYSSFV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ipgD mutant is unable to dephosphorylate phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] and induces shorter filapodia in host cells (Niebuhr et al., 2002).
References
Niebuhr et al., 2002: Niebuhr K, Giuriato S, Pedron T, Philpott DJ, Gaits F, Sable J, Sheetz MP, Parsot C, Sansonetti PJ, Payrastre B. Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology. The EMBO journal. 2002; 21(19); 5069-5078. [PubMed: 12356723].