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ipaC from Shigella boydii CDC 3083-94

Victor ID 1678
Gene Name ipaC from Shigella boydii CDC 3083-94
Sequence Strain (Species/Organism) Shigella boydii CDC 3083-94
NCBI Gene ID 6273424
NCBI Protein GI 187734325
Locus Tag SbBS512_A0159
Protein Accession YP_001883188.1
Other Database IDs UniProtKB-ID: B2TSX6_SHIB3
UniRef100: UniRef100_B2TSX6
UniRef90: UniRef90_Q03946
UniRef50: UniRef50_P18012
UniParc: UPI000173FBDD
EMBL: CP001062
EMBL-CDS: ACD06096.1
RefSeq_NT: NC_010660.1
EnsemblGenome: EBESCG00000074720.
EnsemblGenome_TRS: EBESCT00000075673
EnsemblGenome_PRO: EBESCP00000072822
GenomeReviews: CP001062_GR
KEGG: sbc:SbBS512_A0159
HOGENOM: HBG683609
OMA: ISQASSK
ProtClustDB: CLSK862847
Taxonomy ID 344609
Plasmid No pBS512_211
Gene Starting Position 105409
Gene Ending Position 106500
Gene Strand (Orientation) -
Protein Name invasin protein IpaC
DNA Sequence 
>gi|187734273:105409-106500 Shigella boydii CDC 3083-94 plasmid pBS512_211, complete sequence
ATTAAGCTCGAATGTTACCAGCAATCTGACTGGCTGTAGAATTCCTTGATTGGTTGATGTTGTCAATTAT
ATTCAATAATTTTTGTATTAATTGATTTGTCGCTTGGGATGCTTCTTTAGATACTTGGGATGCTTCCTCT
GCTTGTTTACTGCTGGCCTGACTGATTAGTTGTTCTTCTTCTTCAAGAGCAGATGTATAACGCCCTCCTG
ATGTGGATATATTACCAGCAACGGCTGATGTCTCCATTGTTGCACGGCCAATGTTTTGTTTTTGCTGAGC
AGAAAGGGTATTGAGCTCGTAAGCTCTTCTCTGGGTGTCAATTTTATCCTGCAAAGAAATATCGGGAGAA
CTAAGAGAAGTTTTATGTTCAGTTGACAGGGATATATTATCTGGTGCCAGTTTATTTTTACCTAAAATTT
TTGTGCTAGAGTTAGTTTGTGGTGAGGTGATATTTGTATCTATTTGTTTATTTAACCCTAATTTAGAACC
TGCAAGCTCTTTTTCAAGAGATTGAGCAGTGGCAAGGTTCTTTCTTAAGGCTCCTTTTTGTTCGCTTATC
CCTGAATGCGTTTTTTTGGCACCGATACCCGTTATACCTACTTGTGTGACCGCTCCAGTAATGCTTGATG
ATAGGGCTGCTAGGCCTTGCCGAACAATGTTCTCTGCAGCTGATTTTGTAGCATCGAACGCAATCAATGA
CAATTGAGAGCCCAATCTAGTTTCTGCAGTGCGGAGAGCAGAAAGTAGAACGGCTACACTAATAATTAAA
GAAACAGCATTAGAAGAAAGACTGGAAATATCCAGGGTGTTCTCTGGAGTAATTGTGTGACTCATTTCTG
AAAGATCTTTCATCTTTTTGTCAGTAAGGCGAGCAATGATTTCTGAATCATGCTGAACCTGCTCTGATAA
CTTCAAAAGTTGATCATCATTTAATGTAGTTGTTAATACGGGATTTTTACCGACATTAAGTGGAATATGT
GCTGCTAACTGCTGATAATTTTGTGATTTTTGTGTTTCGGAAGAACTTTGAGTTTGTTTTGTGGATATAT
CTGTATATAAAATCGAGGCTGATTTTGTGTTTTGAATTTCCA
Protein Sequence 
>gi|187734325|ref|YP_001883188.1| invasin protein IpaC [Shigella boydii CDC 3083-94] MEIQNTKSASILYTDISTKQTQSSSETQKSQNYQQLAAHIPLNVGKNPVLTTTLNDDQLLKLSEQVQHDSEIIARLTDKKMKDLSEMSHTITPENTLDISSLSSNAVSLIISVAVLLSALRTAETRLGSQLSLIAFDATKSAAENIVRQGLAALSSSITGAVTQVGITGIGAKKTHSGISEQKGALRKNLATAQSLEKELAGSKLGLNKQIDTNITSPQTNSSTKILGKNKLAPDNISLSTEHKTSLSSPDISLQDKIDTQRRAYELNTLSAQQKQNIGRATMETSAVAGNISTSGGRYTSALEEEEQLISQASSKQAEEASQVSKEASQATNQLIQKLLNIIDNINQSRNSTASQIAGNIRA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ipaC mutants cannot invade cultured cells or lyse red blood cells (Terry et al., 2008).
References
Terry et al., 2008: Terry CM, Picking WL, Birket SE, Flentie K, Hoffman BM, Barker JR, Picking WD. The C-terminus of IpaC is required for effector activities related to Shigella invasion of host cells. Microbial pathogenesis. 2008; 45(4); 282-289. [PubMed: 18656530].