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guaB from Shigella boydii CDC 3083-94

Victor ID 1671
Gene Name guaB from Shigella boydii CDC 3083-94
Sequence Strain (Species/Organism) Shigella boydii CDC 3083-94
NCBI Gene ID 6271528
NCBI Protein GI 187733701
Locus Tag SbBS512_E2883
Protein Accession YP_001881299.1
Other Database IDs UniProtKB-ID: B2TXT3_SHIB3
UniRef100: UniRef100_P0ADG8
UniRef90: UniRef90_P0ADG8
UniRef50: UniRef50_O50316
UniParc: UPI00000480C2
EMBL: CP001063
EMBL-CDS: ACD09967.1
RefSeq_NT: NC_010658.1
EnsemblGenome: EBESCG00000073509.
EnsemblGenome_TRS: EBESCT00000074462
EnsemblGenome_PRO: EBESCP00000071781
GenomeReviews: CP001063_GR
KEGG: sbc:SbBS512_E2883
HOGENOM: HBG298985
OMA: CVGLITV
ProtClustDB: PRK05567
Taxonomy ID 344609
Gene Starting Position 2682050
Gene Ending Position 2683516
Gene Strand (Orientation) -
Protein Name inosine-5'-monophosphate dehydrogenase
DNA Sequence 
>gi|187730020:2682050-2683516 Shigella boydii CDC 3083-94 chromosome, complete genome
ATCAGGAGCCCAGACGGTAGTTCGGGGACTCTTTAGTAATGGTCACGTCGTGAACGTGGCTTTCCTGAAT
GCCCGCACCGCTGATACGTACAAACTCCGCTTTAGTACGCAGTTCGTCGATAGTACCACAGCCGGTCAGG
CCCATACAGGAGCGCAGGCCGCCCATCTGCTGGTGAATGATCTCTTTCAGGCGACCTTTATAGGCTACGC
GACCTTCGATACCTTCCGGCACCAGTTTGTCGGCAGCGTTGTCACTCTGGAAGTAACGGTCAGAAGAACC
TTTGGACATCGCACCCAGAGAGCCCATACCACGGTAAGATTTGTAAGAACGGCCCTGGTAGAGTTCAATT
TCACCCGGAGATTCTTCAGTACCCGCCAGCATGGAACCCACCATTACCGCGCTTGCGCCAGCGGCGATAG
CTTTGGCGATGTCGCCGGAGAAGCGAATACCACCATCTGCGATAACCGGAATACCTGTGCCTTCCAGCGC
TTCAACTGCGTCAGCAACGGCAGTGATCTGCGGAACACCTACGCCAGTAACGATACGAGTCGTACAGATA
GAACCAGGGCCGATACCGACTTTAACCGCGCTGCAACCAGCTTCTGCCAAAGCGCGTGCACCTGCAGCTG
TTGCCACGTTGCCGCCGATGATTTGCAGATCCGGATATTTAGCACGGGTTTCACGGATACGCTGCAAAAC
GCCTTCTGAGTGGCCGTGGGAGGAGTCGATCAGCAGAACGTCAACGCCAGCGGCAACCAGCGCGTCAACA
CGCTCTTCGTTACCCGCACCTGCGCCAACTGCAGCACCAACACGCAGACGGCCTTGCTCGTCTTTACAGG
CGTTCGGTTTACGTTCCGCTTTCTGGAAGTCTTTCACGGTGATCATGCCGATCAGGTGGAATTCGTCATC
AACCACCAGCGCTTTTTCAACGCGTTTTTCGTGCATTTTTGCCAGCACCACTTCACGGGCTTCACCTTCA
CGCACGGTGACCAGACGCTCTTTCGGCGTCATGTAAACGCTAACCGGCTGGTTCAGGTCGGTAACAAAAC
GCACGTCACGACCGGTGATAATACCCACCAGTTCGTTTTCTTCGGTAACAACCGGATAGCCCGCAAAACC
GTTACGCTCGGTCAGTTCTTTCACTTCGCGCAGCGTCGTGGTTGGCAGAACAGTCTGCGGATCAGTCACC
ACACCAGATTCGTGTTTTTTCACACGGCGAACTTCTTCTGCCTGGCGTTCAATGGACATGTTTTTGTGGA
TAAAGCCGATACCGCCTTCCTGAGCCAGAGCAATAGCCAGGCGCGCTTCCGTTACGGTATCCATTGCTGC
GGAAAGCATAGGGATATTCAGACGAATAGTTTTCGTCAGCTGGGTGCTGAGGTCAGCAGTATTCGGCAGA
ACGGTAGAATGAGCAGGAACGAGGAGAACGTCGTCAAACGTCAGAGCTTCTTTAGCGATACGTAGCA
Protein Sequence 
>gi|187733701|ref|YP_001881299.1| inosine 5'-monophosphate dehydrogenase [Shigella boydii CDC 3083-94] MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: guaAguaB mutants are attenuated in HeLa cells (Noriega et al., 1996).
COG COG0516F, under F: Nucleotide transport and metabolism
References
Noriega et al., 1996: Noriega FR, Losonsky G, Lauderbaugh C, Liao FM, Wang JY, Levine MM. Engineered deltaguaB-A deltavirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine. Infection and immunity. 1996; 64(8); 3055-3061. [PubMed: 8757833].