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Rv3876

Victor ID 166
Gene Name Rv3876
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886206
NCBI Protein GI 15611012
Locus Tag Rv3876
Protein Accession NP_218393.1
Other Database IDs UniProtKB-ID: ESPI_MYCTU
UniRef100: UniRef100_O69740
UniRef90: UniRef90_O69740
UniRef50: UniRef50_O69740
UniParc: UPI00000D105D
EMBL: BX842584
EMBL: AE000516
EMBL-CDS: CAA17968.1
EMBL-CDS: AAK48358.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
TCDB: 9.A.25.1.1
EnsemblGenome: EBMYCG00000002643
EnsemblGenome_TRS: EBMYCT00000002645
EnsemblGenome_PRO: EBMYCP00000002645
EnsemblGenome: EBMYCG00000069882
EnsemblGenome_TRS: EBMYCT00000069887
EnsemblGenome_PRO: EBMYCP00000067946
GenomeReviews: AE000516
Taxonomy ID 83332
Gene Starting Position 4353009
Gene Ending Position 4355009
Gene Strand (Orientation) +
Protein Name CONSERVED HYPOTHETICAL PROLINE AND ALANINE RICH PROTEIN
DNA Sequence 
>gi|57116681:4353009-4355009 Mycobacterium tuberculosis H37Rv, complete genome
CATGGCGGCCGACTACGACAAGCTCTTCCGGCCGCACGAAGGTATGGAAGCTCCGGACGATATGGCAGCG
CAGCCGTTCTTCGACCCCAGTGCTTCGTTTCCGCCGGCGCCCGCATCGGCAAACCTACCGAAGCCCAACG
GCCAGACTCCGCCCCCGACGTCCGACGACCTGTCGGAGCGGTTCGTGTCGGCCCCGCCGCCGCCACCCCC
ACCCCCACCTCCGCCTCCGCCAACTCCGATGCCGATCGCCGCAGGAGAGCCGCCCTCGCCGGAACCGGCC
GCATCTAAACCACCCACACCCCCCATGCCCATCGCCGGACCCGAACCGGCCCCACCCAAACCACCCACAC
CCCCCATGCCCATCGCCGGACCCGAACCGGCCCCACCCAAACCACCCACACCTCCGATGCCCATCGCCGG
ACCTGCACCCACCCCAACCGAATCCCAGTTGGCGCCCCCCAGACCACCGACACCACAAACGCCAACCGGA
GCGCCGCAGCAACCGGAATCACCGGCGCCCCACGTACCCTCGCACGGGCCACATCAACCCCGGCGCACCG
CACCAGCACCGCCCTGGGCAAAGATGCCAATCGGCGAACCCCCGCCCGCTCCGTCCAGACCGTCTGCGTC
CCCGGCCGAACCACCGACCCGGCCTGCCCCCCAACACTCCCGACGTGCGCGCCGGGGTCACCGCTATCGC
ACAGACACCGAACGAAACGTCGGGAAGGTAGCAACTGGTCCATCCATCCAGGCGCGGCTGCGGGCAGAGG
AAGCATCCGGCGCGCAGCTCGCCCCCGGAACGGAGCCCTCGCCAGCGCCGTTGGGCCAACCGAGATCGTA
TCTGGCTCCGCCCACCCGCCCCGCGCCGACAGAACCTCCCCCCAGCCCCTCGCCGCAGCGCAACTCCGGT
CGGCGTGCCGAGCGACGCGTCCACCCCGATTTAGCCGCCCAACATGCCGCGGCGCAACCTGATTCAATTA
CGGCCGCAACCACTGGCGGTCGTCGCCGCAAGCGTGCAGCGCCGGATCTCGACGCGACACAGAAATCCTT
AAGGCCGGCGGCCAAGGGGCCGAAGGTGAAGAAGGTGAAGCCCCAGAAACCGAAGGCCACGAAGCCGCCC
AAAGTGGTGTCGCAGCGCGGCTGGCGACATTGGGTGCATGCGTTGACGCGAATCAACCTGGGCCTGTCAC
CCGACGAGAAGTACGAGCTGGACCTGCACGCTCGAGTCCGCCGCAATCCCCGCGGGTCGTATCAGATCGC
CGTCGTCGGTCTCAAAGGTGGGGCTGGCAAAACCACGCTGACAGCAGCGTTGGGGTCGACGTTGGCTCAG
GTGCGGGCCGACCGGATCCTGGCTCTAGACGCGGATCCAGGCGCCGGAAACCTCGCCGATCGGGTAGGGC
GACAATCGGGCGCGACCATCGCTGATGTGCTTGCAGAAAAAGAGCTGTCGCACTACAACGACATCCGCGC
ACACACTAGCGTCAATGCGGTCAATCTGGAAGTGCTGCCGGCACCGGAATACAGCTCGGCGCAGCGCGCG
CTCAGCGACGCCGACTGGCATTTCATCGCCGATCCTGCGTCGAGGTTTTACAACCTCGTCTTGGCTGATT
GTGGGGCCGGCTTCTTCGACCCGCTGACCCGCGGCGTGCTGTCCACGGTGTCCGGTGTCGTGGTCGTGGC
AAGTGTCTCAATCGACGGCGCACAACAGGCGTCGGTCGCGTTGGACTGGTTGCGCAACAACGGTTACCAA
GATTTGGCGAGCCGCGCATGCGTGGTCATCAATCACATCATGCCGGGAGAACCCAATGTCGCAGTTAAAG
ACCTGGTGCGGCATTTCGAACAGCAAGTTCAACCCGGCCGGGTCGTGGTCATGCCGTGGGACAGGCACAT
TGCGGCCGGAACCGAGATTTCACTCGACTTGCTCGACCCTATCTACAAGCGCAAGGTCCTCGAATTGGCC
GCAGCGCTATCCGACGATTTCGAGAGGGCTGGACGTCGTTG
Protein Sequence 
>gi|15611012|ref|NP_218393.1| ESX-1 secretion-associated protein EspI [Mycobacterium tuberculosis H37Rv] MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTPPPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTPPMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQLAPPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEPPPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQRNSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSLRPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEKYELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRILALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLEVLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVLSTVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRACVVINHIMPGEPNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVLELAAALSDDFERAGRR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0455D, under D: Cell cycle control, cell division, chromosome partitioning
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].