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phoP from Shigella boydii CDC 3083-94

Victor ID 1659
Gene Name phoP from Shigella boydii CDC 3083-94
Sequence Strain (Species/Organism) Shigella boydii CDC 3083-94
NCBI Gene ID 6269245
NCBI Protein GI 187730593
Locus Tag SbBS512_E1308
Protein Accession YP_001879938.1
Other Database IDs UniProtKB-ID: B2TZ83_SHIB3
UniRef100: UniRef100_Q8CXZ9
UniRef90: UniRef90_Q57QC3
UniRef50: UniRef50_Q5PMJ1
UniParc: UPI000000E0F8
EMBL: CP001063
EMBL-CDS: ACD06859.1
RefSeq_NT: NC_010658.1
EnsemblGenome: EBESCG00000072686.
EnsemblGenome_TRS: EBESCT00000073639
EnsemblGenome_PRO: EBESCP00000070958
GenomeReviews: CP001063_GR
KEGG: sbc:SbBS512_E1308
HOGENOM: HBG753323
OMA: HIEEVVA
ProtClustDB: PRK10816
Taxonomy ID 344609
Gene Starting Position 1194684
Gene Ending Position 1195355
Gene Strand (Orientation) -
Protein Name DNA-binding response regulator PhoP
DNA Sequence 
>gi|187730020:1194684-1195355 Shigella boydii CDC 3083-94 chromosome, complete genome
ATCAGCGCAATTCGAACAAATAGCCCTGGCCGCGAACGGTAGTAATCACTTCTTGCGGATATTGTGCCTG
AATTTTTTTGCGCAGACGTCCCATCAGTACATCAATGGTATGGCTTTCCCGCAGCTCCGCATCCGGATAG
AGTTGGAGCATTAACGAATCTTTGCTCACCACTTTGCCATTATTGCGTATCAACGTTTCCATAATGGTGT
ATTCGAACGCGGTCAGTTTGATCACTTCGTCATTAATAGATAATTCACGGCGAGAGAGATCAACCTGAAA
CGGTGGTAGCGAAATGACCTGTGAAGCCAGACCGCTATTACGCCGCATTAATGCCTGCATTCGCGCCATC
ACCTCTTCAATATGAAATGGTTTAGTCACGTAATCATCAGCACCAGCACTTAATACTTCGACTTTGTCCT
GCCAGCTTTCACGGGCGGTTAATACCAGAATCGGCAGTGAAACATCATTGCTACGCCAGCGGCGAATCAG
TGACAGACCGTCCTCGTCTGGCAATCCGAGATCGACAATCGCAATATCCGGTAAATGTTCATTGAGATAA
TAATCGGCTTCTTTGGCATCTTCTGCATCATCGACCTGATGACCAGCATCCTGAATCTGAACTTTAAGGT
GGTGACGTAACAACGCATTGTCTTCAACAACCAGTACGCGCA
Protein Sequence 
>gi|187730593|ref|YP_001879938.1| DNA-binding transcriptional regulator PhoP [Shigella boydii CDC 3083-94] MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGYLFELR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: phoP mutants were resolved more quickly than wild type in animal models, and are more susceptible to killing by PMNs (Moss et al., 2000).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Moss et al., 2000: Moss JE, Fisher PE, Vick B, Groisman EA, Zychlinsky A. The regulatory protein PhoP controls susceptibility to the host inflammatory response in Shigella flexneri. Cellular microbiology. 2000; 2(6); 443-452. [PubMed: 11207599].