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degP

Victor ID 1655
Gene Name degP
Sequence Strain (Species/Organism) Shigella boydii CDC 3083-94
NCBI Gene ID 6268800
NCBI Protein GI 187732326
Locus Tag SbBS512_E0154
Protein Accession YP_001878964.1
Other Database IDs UniProtKB-ID: B2U305_SHIB3
UniRef100: UniRef100_P0C0V1
UniRef90: UniRef90_P0C0V1
UniRef50: UniRef50_P26982
UniParc: UPI0000129175
EMBL: CP001063
EMBL-CDS: ACD08592.1
RefSeq_NT: NC_010658.1
MEROPS: S01.273
EnsemblGenome: EBESCG00000072283.
EnsemblGenome_TRS: EBESCT00000073236
EnsemblGenome_PRO: EBESCP00000070555
GenomeReviews: CP001063_GR
KEGG: sbc:SbBS512_E0154
HOGENOM: HBG585708
OMA: ISINIEG
ProtClustDB: PRK10942
Taxonomy ID 344609
Gene Starting Position 167763
Gene Ending Position 169187
Gene Strand (Orientation) +
Protein Name protease Do
DNA Sequence 
>gi|187730020:167763-169187 Shigella boydii CDC 3083-94 chromosome, complete genome
CATGAAAAAAACCACATTAGCACTGAGTGCACTGGCTCTGAGTTTAGGTTTGGCGTTATCTCCGCTCTCT
GCAACGGCGGCTGAGACTTCTTCAGCAACGACAGCCCAGCAGATGCCAAGCCTTGCACCGATGCTCGAAA
AGGTGATGCCTTCAGTGGTCAGCATTAACGTAGAAGGTAGCACAACCGTTAATACGCCGCGTATGCCGCG
TAATTTCCAGCAGTTCTTCGGTGATGATTCTCCGTTCTGCCAGGAAGGTTCTCCGTTCCAGAGCTCTCCG
TTCTGCCAGGGTGGCCAGGGCGGTAATGGTGGCGGCCAGCAACAGAAATTCATGGCGCTGGGTTCCGGCG
TCATCATTGATGCCGATAAAGGCTATGTCGTCACCAACAACCACGTTGTTGATAACGCGACGGTGATTAA
AGTCCAGCTGAGCGATGGCCGTAAGTTCGACGCGAAGATGGTCGGCAAAGATCCGCGCTCTGATATCGCG
CTGATCCAAATCCAGAACCCGAAAAACCTGACCGCAATTAAGATGGCGGATTCTGATGCACTGCGCGTGG
GTGATTACACCGTAGCGATTGGTAACCCGTTTGGTCTGGGCGAGACGGTAACTTCCGGGATTGTCTCTGC
GCTGGGGCGTAGCGGCCTGAATGCTGAAAACTACGAAAACTTCATCCAGACCGATGCAGCGATCAACCGT
GGTAACTCCGGTGGTGCGCTGGTTAACCTGAACGGCGAACTGATCGGTATCAACACCGCGATCCTCGCAC
CGGACGGCGGCAACATCGGTATCGGTTTTGCAATCCCGAGCAACATGGTGAAAAACCTGACCTCGCAGAT
GGTGGAATACGGCCAGGTGAAACGCGGTGAGCTGGGTATTATGGGGACTGAGCTGAACTCCGAACTGGCG
AAAGCGATGAAAGTTGACGCCCAGCGCGGTGCTTTCGTAAGCCAGGTTCTGCCTAATTCCTCCGCTGCAA
AAGCGGGCATTAAAGCGGGTGATGTGATCACCTCACTGAACGGTAAGCCGATCAGCAGCTTTGCCGCACT
GCGTGCTCAGGTGGGTACTATGCCGGTGGGCAGCAAACTGACCCTGGGCTTACTGCGCGACGGTAAGCAG
GTTAACGTGAACCTGGAACTGCAGCAGAGCAGCCAGAATCAGGTTGATTCCAGCTCCATCTTCAACGGCA
TTGAAGGCGCTGAGATGAGCAACAAAGGCAAAGATCAGGGCGTGGTAGTGAACAACGTGAAAACGGGCAC
TCCGGCTGCGCAGATCGGCCTGAAGAAAGGTGATGTGATTATTGGCGCGAACCAGCAGGCAGTGAAAAAC
ATCGCTGAACTGCGTAAAGTTCTCGACAGCAAACCGTCTGTGCTGGCACTGAACATTCAGCGCGGCGACA
GCACCATCTACCTGTTAATGCAGTA
Protein Sequence 
>gi|187732326|ref|YP_001878964.1| serine endoprotease [Shigella boydii CDC 3083-94] MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPMLEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGNGGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLTSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGDVITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSSIFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKVLDSKPSVLALNIQRGDSTIYLLMQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: degP mutant is unable to form plaques on Henle cell monolayers (Purdy et al., 2007).
COG COG0265O, under O: Posttranslational modification, protein turnover, chaperones
References
Purdy et al., 2007: Purdy GE, Fisher CR, Payne SM. IcsA surface presentation in Shigella flexneri requires the periplasmic chaperones DegP, Skp, and SurA. Journal of bacteriology. 2007; 189(15); 5566-5573. [PubMed: 17526712].