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panC from Mycobacterium tuberculosis F11

Victor ID 1651
Gene Name panC from Mycobacterium tuberculosis F11
Sequence Strain (Species/Organism) Mycobacterium tuberculosis F11
NCBI Gene ID 5224323
NCBI Protein GI 148824807
Locus Tag TBFG_13634
Protein Accession YP_001289561.1
Other Database IDs UniProtKB-ID: A5WTH0_MYCTF
UniRef100: UniRef100_A1KPT7
UniRef90: UniRef90_A1KPT7
UniRef50: UniRef50_A0PV50
UniParc: UPI000013129B
EMBL: CP000717
EMBL-CDS: ABR07959.1
RefSeq_NT: NC_009565.1
GenomeReviews: CP000717_GR
KEGG: mtf:TBFG_13634
OMA: EDFGSYP
ProtClustDB: PRK00380
BioCyc: MTUB336982:TBFG_13634-MONOMER
Taxonomy ID 336982
Gene Starting Position 4057061
Gene Ending Position 4057990
Gene Strand (Orientation) -
Protein Name pantoate--beta-alanine ligase
DNA Sequence 
>gi|148821191:4057061-4057990 Mycobacterium tuberculosis F11, complete genome
ATCAGTTTCTCCAATGTGATTCGAGGATTGCCCGGTATCCGTCCGGGCGGTCGGTGCCGGCGAAAGTTCC
GATTTCAATCGCAATGTTGTCCAGCAGCCTGGTGGTGCCAAGCCGGGCAGCAACCAGCAGCCGACCGGAA
CCGTTGAGCGGCATCGGGCCAAGCCCGATATCGCGCAGCTCCAGGTAGTCGACCGCCACGCCGGGTGCAG
CGTCGAGCACCGCACGGGCGGCATCCAGCGCGGCCTGCGCGCCAGCCGTTGCCGCATGCGCTGCGGCCGT
TAGCGCCGCCGAGAGCGCGACGGCCGCCGCACGCTGGGCCGGGTCCAGGTAGCGGTTGCGCGACGACATC
GCCAGCCCGTCGGCTTCGCGCACGGTCGGCACGCCGACCACCGCGACATCGAGGTTGAAGTCCGCGACCA
GCTGCCGGATCAGCACCAGCTGCTGGTAGTCCTTCTCACCGAAGAACACCCGATCCGGGCGCACGATCTG
CAGCAGCTTTAGCACGACCGTCAGCACGCCGGCGAAATGGGTTGGCCGCGGGCCGCCCTCGAGTTCGGCG
GCCAACGGACCGGGTTGCACGGTGGTGCGCAGGCCGTCGGGATACATCGCCGCGGTAGTTGGCGTGAAAG
CGATTTCCACGCCTTCGGCCCGCAGTTGCGCCAGGTCGTCGTCCGGGGTGCGGGGATAGGCGTCGAGATC
TTCCCCGGCACCGAATTGCATCGGGTTGACGAAGATCGACACGACGACGACCGATCCGGGCACCCGCTTG
GCCGCACGCACCAACGCGAGGTGGCCTTCGTGCAGCGCACCCATAGTAGGCACCAACATCACTCGCCGGC
CGGTGAGTCGCAGTGCGCGACTGACATCGGCGACATCCCCCGGTGCCGAGTACACATTGAGTTCACCGGG
ATGGAACGCAGGAATCGTCA
Protein Sequence 
>gi|148824807|ref|YP_001289561.1| pantoate--beta-alanine ligase [Mycobacterium tuberculosis F11] MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYRAILESHWRN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pan CD mutant is attenuated in mice (Sambandamurthy et al., 2002).
COG COG0414H, under H: Coenzyme transport and metabolism
References
Sambandamurthy et al., 2002: Sambandamurthy VK, Wang X, Chen B, Russell RG, Derrick S, Collins FM, Morris SL, Jacobs WR Jr. A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis. Nature medicine. 2002; 8(10); 1171-1174. [PubMed: 12219086].