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leuD from Mycobacterium tuberculosis F11

Victor ID 1650
Gene Name leuD from Mycobacterium tuberculosis F11
Sequence Strain (Species/Organism) Mycobacterium tuberculosis F11
NCBI Gene ID 5223688
NCBI Protein GI 148824177
Locus Tag TBFG_13002
Protein Accession YP_001288931.1
Other Database IDs UniProtKB-ID: A5WRP0_MYCTF
UniRef100: UniRef100_A1KMY1
UniRef90: UniRef90_A1KMY1
UniRef50: UniRef50_A0ZZS8
UniParc: UPI000012E58F
EMBL: CP000717
EMBL-CDS: ABR07329.1
RefSeq_NT: NC_009565.1
GenomeReviews: CP000717_GR
KEGG: mtf:TBFG_13002
OMA: TLQHADK
ProtClustDB: PRK01641
BioCyc: MTUB336982:TBFG_13002-MONOMER
Taxonomy ID 336982
Gene Starting Position 3355741
Gene Ending Position 3356337
Gene Strand (Orientation) -
Protein Name isopropylmalate isomerase small subunit
DNA Sequence 
>gi|148821191:3355741-3356337 Mycobacterium tuberculosis F11, complete genome
CTCAGGGGGCGGGTAGAGTGCGCGGTTTCCAGTACGCGCACGCACCCTCAAAGGCCTCGATCTCGTCGAG
TTTCCGCAGCGTAAGGGCTATATCGTCGAGACCTTCAAGCAGCCGCCACGCCGAGTGGTCGTCAATCTTG
AACGGCAGCACCACTGTTGCTGCGGTGATAATTCGATCTTGAAGATTGGCAGTGATTTCCAGGCCCGGAC
TCTGCTCAATGAGCTTCCACAGGAGTTCCACATCGTCTTGGGCAACCTCGGCCGCCAGCAGCCCGGCCTT
GCCCGCGTTGCCGCGGAAAATGTCACCAAATCGGGATGAGATAACCACCCGGAATCCGTAGTCCATGAGC
GCCCAGACCGCATGCTCTCGCGAGGATCCGGTGCCGAAATCGGGCCCGGCAACCAGGACCGAACCCCGGT
CAAAGGGACTGAGGTTTAGCACGAATGCAGGATCCGACCGCCAACCCGCGAACAAGCCGTCCTCGAAACC
GGTTCGGGTGACCCGCTTCAGAAAGACCGCGGGAATGATCTGATCGGTGTCGACATTGGACCGCCGCAAC
GGCACGCCAATACCAGAGTGGGTGTGAAAGGCTTCCA
Protein Sequence 
>gi|148824177|ref|YP_001288931.1| isopropylmalate isomerase small subunit [Mycobacterium tuberculosis F11] MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDPAFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQDRIITAATVVLPFKIDDHSAWRLLEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: leuD mutant is attenuated in mice (Hondalus et al., 2000).
COG COG0066E, under E: Amino acid transport and metabolism
References
Hondalus et al., 2000: Hondalus MK, Bardarov S, Russell R, Chan J, Jacobs WR Jr, Bloom BR. Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis. Infection and immunity. 2000; 68(5); 2888-2898. [PubMed: 10768986].