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trpD from Mycobacterium tuberculosis F11

Victor ID 1649
Gene Name trpD from Mycobacterium tuberculosis F11
Sequence Strain (Species/Organism) Mycobacterium tuberculosis F11
NCBI Gene ID 5222896
NCBI Protein GI 148823399
Locus Tag TBFG_12220
Protein Accession YP_001288153.1
Other Database IDs UniProtKB-ID: A5WPG2_MYCTF
UniRef100: UniRef100_A1KKN4
UniRef90: UniRef90_A1KKN4
UniRef50: UniRef50_A1KKN4
UniParc: UPI000013758F
EMBL: CP000717
EMBL-CDS: ABR06551.1
RefSeq_NT: NC_009565.1
GenomeReviews: CP000717_GR
KEGG: mtf:TBFG_12220
OMA: LGVYSPE
ProtClustDB: PRK00188
BioCyc: MTUB336982:TBFG_12220-MONOMER
Taxonomy ID 336982
Gene Starting Position 2467833
Gene Ending Position 2468945
Gene Strand (Orientation) -
Protein Name anthranilate phosphoribosyltransferase
DNA Sequence 
>gi|148821191:2467833-2468945 Mycobacterium tuberculosis F11, complete genome
GTCAGATCTGCCGACCGAACCGCACCCATCGCGCGAGCAACTGTTCGGCCGCACCGGTGTCGATTGCCGC
ACTGGCCCGCCGCAACCCCTCCTCCCAGGCCGGCAGCCATTCAGCACGGCTGGATAATCCGGCGTGGGCG
ACGATCGCACCGGCGGCGTTGAGCACCACAGCGTCCCGGACCGGGCCCCTGGCACCGCCCAACACCGCGC
GCACCGCGGCCGCGTTGGCTTGCGCATCGCCTCCAGCCAGCTGGTCAAGCTGGGCGCGCGCAAACCCGAA
TCCGGCGGGATCAAACGTCAACTTATCCACGCTGCCCGCCGCAACGCGCCAGATCGTGCTCGTGGTGGTG
GTGGTCAACTCGTCCAGCCCATCGTCGCCGTGTACCACCAGCACACTGGACCGGCGCGCAGCAAACACCC
CGGCCATCACTTCGGCGAGGTCGGCGAACGCGCATCCGATCAGTCCAGCCCGGGGCCGGGCCGGATTGGT
CAGCGGCCCGAGAAGATTGAACACGGTGGGCACACCGATCTCGCGGCGTACCGCGGCCGCGTGCCGGTAG
GAGGGATGGAACCGCGGCGCGAAGCAGAACCCGATCCCAACCTCCGCGAGGCTGCGCGCGACCAGGTCGG
GTCCCAGGTCGATGCGCACCCCCAGCGCCTCCAGCGTGTCGGCGCCACCGGACAACGAGGACGCCGCTCG
GTTGCCGTGCTTGACCACCGGCACACCCGCAGCCGCCACCACAATCGCCGCCATGGTGGATAGGTTCACC
GTGTTGACTCCGTCGCCACCGGTGCCGACGACGTCGACGGCGTCGTCGGGGACCGTATCGGCGGGCAACG
GATGCGCGTGGCTGAGCATGACGCCAGCGAGCTCACCGACTTCGTCGGCGGTCGGAGCCTTCATCGTCAT
CGCCACCGCGAAGGCGGCGATCTGCGCCGGCCGCGCATTGCCGGTCATGATCTGGTCCATGGCCCAGGCA
GCCTGGCCCCGCGCCAGATCGCGGTTGTCGGTCAACCGCCCCAAAATCTGCGGCCAGGACGGCACCGATG
CGGCTTCTGCTTTCGGCGAGCCCCCGCGAGATCCCCCCGAAGAACCCTCAGCTGACAGCGCCA
Protein Sequence 
>gi|148823399|ref|YP_001288153.1| anthranilate phosphoribosyltransferase [Mycobacterium tuberculosis F11] MALSAEGSSGGSRGGSPKAEAASVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trpD mutant is attenuated in mice (Smith et al., 2001).
COG COG0547E, under E: Amino acid transport and metabolism
References
Smith et al., 2001: Smith DA, Parish T, Stoker NG, Bancroft GJ. Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates. Infection and immunity. 2001; 69(2); 1142-1150. [PubMed: 11160012].