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lspA from Mycobacterium tuberculosis F11

Victor ID 1648
Gene Name lspA from Mycobacterium tuberculosis F11
Sequence Strain (Species/Organism) Mycobacterium tuberculosis F11
NCBI Gene ID 5222252
NCBI Protein GI 148822762
Locus Tag TBFG_11572
Protein Accession YP_001287517.1
Other Database IDs UniProtKB-ID: A5WMM6_MYCTF
UniRef100: UniRef100_A5WMM6
UniRef90: UniRef90_A5WMM6
UniRef50: UniRef50_A1KIW9
UniParc: UPI0000EF4854
EMBL: CP000717
EMBL-CDS: ABR05914.1
RefSeq_NT: NC_009565.1
GenomeReviews: CP000717_GR
KEGG: mtf:TBFG_11572
OMA: SMKVGDS
ProtClustDB: PRK14764
BioCyc: MTUB336982:TBFG_11572-MONOMER
Taxonomy ID 336982
Gene Starting Position 1746814
Gene Ending Position 1747488
Gene Strand (Orientation) +
Protein Name lipoprotein signal peptidase
DNA Sequence 
>gi|148821191:1746814-1747488 Mycobacterium tuberculosis F11, complete genome
CGTGGTTTGCTCCCATCCGGCCGCGGGGTCTGGGCGGGCCATATCGGCCCTAGGGGATGATGATGGTGTG
CCTGACGAACCAACAGGATCGGCTGATCCGCTGACCTCGACCGAGGAAGCCGGGGGGGCGGGGGAACCTA
ACGCTCCCGCGCCGCCGCGACGGCTGCGCATGCTGCTGTCGGTCGCTGTGGTGGTGCTCACACTCGACAT
TGTCACCAAGGTGGTAGCTGTCCAACTGTTGCCGCCCGGCCAGCCGGTGTCGATTATCGGCGACACGGTG
ACCTGGACTCTGGTGCGTAATTCTGGGGCGGCCTTCTCGATGGCGACCGGATACACCTGGGTTTTGACGC
TGATTGCGACGGGTGTCGTGGTCGGAATTTTCTGGATGGGGCGGCGGCTGGTATCGCCGTGGTGGGCGCT
GGGTCTTGGGATGATCCTGGGCGGTGCCATGGGCAACCTGGTTGATCGCTTCTTTCGGGCACCGGGGCCG
CTGCGCGGGCACGTCGTCGATTTCTTGTCGGTCGGCTGGTGGCCGGTGTTCAATGTCGCCGATCCGTCGG
TAGTCGGTGGCGCCATCCTGCTGGTCATCCTGTCGATCTTTGGCTTTGACTTCGACACCGTAGGTCGGCG
ACACGCCGACGGGGACACCGTAGGTCGGCGCAAAGCCGATGGCTG
Protein Sequence 
>gi|148822762|ref|YP_001287517.1| lipoprotein signal peptidase [Mycobacterium tuberculosis F11] MVCSHPAAGSGRAISALGDDDGVPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLSVAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lspA mutant is attenuated in mice (Rampini et al., 2008).
COG COG0597MU, under M: Cell wall/membrane/envelope biogenesis; U: Intracellular trafficking, secretion, and vesicular transport
References
Rampini et al., 2008: Rampini SK, Selchow P, Keller C, Ehlers S, Böttger EC, Sander P. LspA inactivation in Mycobacterium tuberculosis results in attenuation without affecting phagosome maturation arrest. Microbiology (Reading, England). 2008; 154(Pt 10); 2991-3001. [PubMed: 18832305].