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sptP from Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67

Victor ID 1644
Gene Name sptP from Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
NCBI Gene ID 3335312
NCBI Protein GI 62181380
Locus Tag SC2810
Protein Accession YP_217797.1
Other Database IDs UniProtKB-ID: Q57KP6_SALCH
UniRef100: UniRef100_Q57KP6
UniRef90: UniRef90_Q5PEA9
UniRef50: UniRef50_Q5PEA9
UniParc: UPI00004F7F60
EMBL: AE017220
EMBL-CDS: AAX66716.1
RefSeq_NT: NC_006905.1
GenomeReviews: AE017220_GR
KEGG: sec:SC2810
NMPDR: fig|321314.4.peg.2501
HOGENOM: HBG671449
OMA: ALEAHMK
ProtClustDB: CLSK894366
BioCyc: SENT321314:SCH_2810-MONOMER
Taxonomy ID 321314
Gene Starting Position 2975598
Gene Ending Position 2977229
Gene Strand (Orientation) -
Protein Name protein tyrosine phosphate
DNA Sequence 
>gi|62178570:2975598-2977229 Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67 chromosome, complete genome
ATCAGCGTGCCGTCGTCATAAGCAACTGGGCTTGCATTGCTTTTAGTTGTACAAACTGTGAGGCGTCTTC
CAGCATTCTATTGTTCCGTGAATCCCGGAAATCTGCACGTACCTGCTCCAGATTACTATGAGGATTATCC
TTAAGTACAAGGGCCGCCGCCATCGTTCCGGTTCTCCCCACTCCGCCCAAACAATGAATCATCGGTAAAT
GCTTATCTGATGAACTACGCCCCGGCGCGCCATTTTGGTTACTATTTTTCACCCTATCCGCCAGGTATTC
TAACTGATCCGTAGACGGTAACGGCTGGTGATCTGGCCAATTTTTCACATGCAATACCGGGATTGTATAC
CGCTTTTCCCCGCAGGACAGTTGCATATTGTATTGGTCTATCGCTTCTCCCTGACTGGCTGAGCTCACTT
TTTGGCTGTTGGTATGCACCTCGCCAAAGGTGTAGCTCCCTCTGAAATAGGGTGGTAATTGTTTTGCCTG
CATCTGATCTTCCGACGTTAACACCACCAAGCACGAGCATTCTTTTTCAAGAAGCATTTTCATATGCGCT
TCCAGCGCGTCCGGCGTATTTTTTGGGTACGAACCGGCTAATGCCACAGGCTTACCGTCAAAAGTTAACG
TATTCACTGGCACAGGCATTCCATCGCTCAGTTTCACCTGGGTTTGCTGATTAATTGGAATGCTGCTGAC
CGCAAACCGTGCCAGGCCCAGTGTCGGTCCGCTCATCGTCTGTGGCATTGGCGCGCCGGCTTCTATTTTC
TCAAGTTCAGCTGTAACATTTTTCAGTTCTTTAGCAATAACGTGAATTTTTTTTACAGCCTGGGTTAATT
CATGAGTAGAGGCTTTATCAACCCACCTCTCAACCTCTCCTCCACAGGTTCCCCATTGTGAGAACCGGGC
TACACCGACCTGAATATTTGTTAACGTTGTAACATAATCATTAAGTTGTTTAGCCTCTGGAATTTTATTT
AAATTCTGTAAATTCGTCATTAATGAACGCAGCGGGCCGTTACCTGAAGCCATCTCCTGGAAGTTTTCTC
GCAAGCTATTTCCATCCATTTGTTCCAGTTGCGGTAATGTTCTTTTAAGTCCCTTTAGCGCGATATCGAG
TAAAGGTTGCTTACTTTCTGCTCCAACATCGTTATTTTTTTCTGCCACTTTTGTATCGCCGCCTTTTATG
ACTAAAGCGGCATTCCTGACACCAACATTATCCTTGCTCTTAATAAGGTTTATAAACCCTTCGTCAGCAG
CTTTTACACACTCCGTGATCTGCACTGCTAAACGTTGGGTAAGGGGTTTGTTCATATTTATACGGGACAT
TAACAGTGCGTCATTAACCGCTGTTTCCCCATATTTTTCCGTTAGTGCCTGGAGAAATGTCTGTAAAATC
TTTTGGTCCTGTACTCTGATATTTTCCGTATGTTTTTGCACCACTTCAGTGTTTTTAAATAACGGCATTT
TTCCAAGCCAGGTTAATACTTTTGACGAAAGTTTTTCAGGCGCAACATATGCCTTGTCAGTATTTTCCTT
AGCAATATAAAGTCGGGCATCATTCGACACACCAACTTTTGAAAACGAAGACAACGTTAAATTATTCAAT
TTTCTCTCCTCATACTTTAGCA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sptP mutants have reduced epithelial cell invasion and reduced transepithelial migration of PMN compared to the wild type. Competition experiments indicate that sptP mutants fail to colonize the spleen of mice when coinoculated with wild-type S. enterica (Tenor et al., 2004).
COG COG2453T, under T: Signal transduction mechanisms
References
Tenor et al., 2004: Tenor JL, McCormick BA, Ausubel FM, Aballay A. Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Current biology : CB. 2004; 14(11); 1018-1024. [PubMed: 15182677].