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Rv3871

Victor ID 164
Gene Name Rv3871
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886202
NCBI Protein GI 15611007
Locus Tag Rv3871
Protein Accession NP_218388.1
Other Database IDs UniProtKB-ID: ECC1B_MYCTU
UniRef100: UniRef100_O69736
UniRef90: UniRef90_O69736
UniRef50: UniRef50_O69736
UniParc: UPI00000D5F33
EMBL: BX842584
EMBL: AE000516
EMBL-CDS: CAA17963.1
EMBL-CDS: AAK48353.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
TCDB: 9.A.25.1.1
EnsemblGenome: EBMYCG00000003260
EnsemblGenome_TRS: EBMYCT00000003262
EnsemblGenome_PRO: EBMYCP00000003262
EnsemblGenome: EBMYCG00000071823
EnsemblGenome_TRS: EBMYCT00000071828
EnsemblGenome_PRO: EBMYCP00000069887
GenomeReviews: AE00051
Taxonomy ID 83332
Gene Starting Position 4348826
Gene Ending Position 4350601
Gene Strand (Orientation) +
Protein Name hypothetical protein
DNA Sequence 
>gi|57116681:4348826-4350601 Mycobacterium tuberculosis H37Rv, complete genome
CATGACTGCTGAACCGGAAGTACGGACGCTGCGCGAGGTTGTGCTGGACCAGCTCGGCACTGCTGAATCG
CGTGCGTACAAGATGTGGCTGCCGCCGTTGACCAATCCGGTCCCGCTCAACGAGCTCATCGCCCGTGATC
GGCGACAACCCCTGCGATTTGCCCTGGGGATCATGGATGAACCGCGCCGCCATCTACAGGATGTGTGGGG
CGTAGACGTTTCCGGGGCCGGCGGCAACATCGGTATTGGGGGCGCACCTCAAACCGGGAAGTCGACGCTA
CTGCAGACGATGGTGATGTCGGCCGCCGCCACACACTCACCGCGCAACGTTCAGTTCTATTGCATCGACC
TAGGTGGCGGCGGGCTGATCTATCTCGAAAACCTTCCACACGTCGGTGGGGTAGCCAATCGGTCCGAGCC
CGACAAGGTCAACCGGGTGGTCGCAGAGATGCAAGCCGTCATGCGGCAACGGGAAACCACCTTCAAGGAA
CACCGAGTGGGCTCGATCGGGATGTACCGGCAGCTGCGTGACGATCCAAGTCAACCCGTTGCGTCCGATC
CATACGGCGACGTCTTTCTGATCATCGACGGATGGCCCGGTTTTGTCGGCGAGTTCCCCGACCTTGAGGG
GCAGGTTCAAGATCTGGCCGCCCAGGGGCTGGCGTTCGGCGTCCACGTCATCATCTCCACGCCACGCTGG
ACAGAGCTGAAGTCGCGTGTTCGCGACTACCTCGGCACCAAGATCGAGTTCCGGCTTGGTGACGTCAATG
AAACCCAGATCGACCGGATTACCCGCGAGATCCCGGCGAATCGTCCGGGTCGGGCAGTGTCGATGGAAAA
GCACCATCTGATGATCGGCGTGCCCAGGTTCGACGGCGTGCACAGCGCCGATAACCTGGTGGAGGCGATC
ACCGCGGGGGTGACGCAGATCGCTTCCCAGCACACCGAACAGGCACCTCCGGTGCGGGTCCTGCCGGAGC
GTATCCACCTGCACGAACTCGACCCGAACCCGCCGGGACCAGAGTCCGACTACCGCACTCGCTGGGAGAT
TCCGATCGGCTTGCGCGAGACGGACCTGACGCCGGCTCACTGCCACATGCACACGAACCCGCACCTACTG
ATCTTCGGTGCGGCCAAATCGGGCAAGACGACCATTGCCCACGCGATCGCGCGCGCCATTTGTGCCCGAA
ACAGTCCCCAGCAGGTGCGGTTCATGCTCGCGGACTACCGCTCGGGCCTGCTGGACGCGGTGCCGGACAC
CCATCTGCTGGGCGCCGGCGCGATCAACCGCAACAGCGCGTCGCTAGACGAGGCCGTTCAAGCACTGGCG
GTCAACCTGAAGAAGCGGTTGCCGCCGACCGACCTGACGACGGCGCAGCTACGCTCGCGTTCGTGGTGGA
GCGGATTTGACGTCGTGCTTCTGGTCGACGATTGGCACATGATCGTGGGTGCCGCCGGGGGGATGCCGCC
GATGGCACCGCTGGCCCCGTTATTGCCGGCGGCGGCAGATATCGGGTTGCACATCATTGTCACCTGTCAG
ATGAGCCAGGCTTACAAGGCAACCATGGACAAGTTCGTCGGCGCCGCATTCGGGTCGGGCGCTCCGACAA
TGTTCCTTTCGGGCGAGAAGCAGGAATTCCCATCCAGTGAGTTCAAGGTCAAGCGGCGCCCCCCTGGCCA
GGCATTTCTCGTCTCGCCAGACGGCAAAGAGGTCATCCAGGCCCCCTACATCGAGCCTCCAGAAGAAGTG
TTCGCAGCACCCCCAAGCGCCGGTTA
Protein Sequence 
>gi|15611007|ref|NP_218388.1| ESX-1 secretion system protein EccCb [Mycobacterium tuberculosis H37Rv] MTAEPEVRTLREVVLDQLGTAESRAYKMWLPPLTNPVPLNELIARDRRQPLRFALGIMDEPRRHLQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYCIDLGGGGLIYLENLPHVGGVANRSEPDKVNRVVAEMQAVMRQRETTFKEHRVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEGQVQDLAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDRITREIPANRPGRAVSMEKHHLMIGVPRFDGVHSADNLVEAITAGVTQIASQHTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAHCHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGLLDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSRSWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQMSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSSEFKVKRRPPGQAFLVSPDGKEVIQAPYIEPPEEVFAAPPSAG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Rv3871 mutant is attenuated in mice (Stanley et al., 2003).
COG COG1674D, under D: Cell cycle control, cell division, chromosome partitioning
References
Stanley et al., 2003: Stanley SA, Raghavan S, Hwang WW, Cox JS. Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 13001-13006. [PubMed: 14557536].