Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

ospC1 from Shigella sonnei Ss046

Victor ID 1636
Gene Name ospC1 from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3671020
NCBI Protein GI 74314886
Locus Tag SSON_P049
Protein Accession YP_313304.1
Other Database IDs UniProtKB-ID: Q3YTU3_SHISS
UniRef100: UniRef100_Q3YTU3
UniRef90: UniRef90_B2TST5
UniRef50: UniRef50_Q3YTS0
UniParc: UPI00005AACE5
EMBL: CP000039
EMBL-CDS: AAZ91069.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000101972.
EnsemblGenome_TRS: EBESCT00000102928
EnsemblGenome_PRO: EBESCP00000098788
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P049
eggNOG: NOG150778
HOGENOM: HBG683600
OMA: SIANQKE
ProtClustDB: CLSK504963
BioCyc: SSON300269:SSO_P049-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 44738
Gene Ending Position 46150
Gene Strand (Orientation) +
Protein Name secreted by the Mxi-Spa secretion machinery
DNA Sequence 
>gi|74314838:44738-46150 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
TATGAATATATCAGAAACACTGAACTCAGCAAATACCCAATGCAATATAGATTCTATGGATAACAGATTA
CATACATTGTTTCCAAAAGTGACATCAGTGCGAAACGCTGCACAACAAACTATGCCAGATGAAAAAAATT
TAAAAGATAGTGCAAATATTATTAAAGATTTCTTTAGGAAAACTATAGCAGCACAGAGTTATAGTAGAAT
GTTCTCTCAAGGCTCTAACTTTAAATCTTTAAATATAGCAATTGATGCACCATCAGACGCTAAAGCCTCA
TTTAAGGCTATTGAGCACCTTGACAGATTATCGAAGCATTATATATCTGAAATAAGGGAAAAACTTCATC
CTCTTTCTGCAGAGGAACTCAATTTGCTTTCGCTAATTATTAATTCTGATTTAATCTTCAGACATCAAAG
TAATTCTGATTTGTCTGATAAAATTTTAAACATTAAGTCATTCAATAAAATTCAGTCTGAAGGAATATGC
ACAAAACGAAACACATACGCTGATGATATAAAAAAAATAGCTAATCATGACTTTGTGTTTTTTGGCGTTG
AAATCTCTAGCCATCAGAAAAAACACCCCCTGAATACAAAACATCACACTGTTGATTTTGGTGCAAATGC
GTATATCATTGATCATGACTCTCCATATGGATATATGACATTAACCGATCACTTTGATAATGCTATTCCA
CCTGTTTTTTACCATGAGCACCAATCATTTTTAGATAAATTTTCAGAGGTTAATAAAGAAGTTAGTCGAT
ACGTACATGGAAGTAAAGGAATTATAGATGTACCAATATTCAATACTAAAGATATGAAGTTAGGGCTCGG
ATTATACCTGATTGACTTTATTAGAAAAAGTGAAGACCAAAGCTTCAAGGAGTTTTGCTATGGAAAAAAT
CTTGCCCCTGTGGATCTGGATAGAATCATAAACTTTGTTTTTCAGCCAGAGTACCATATACCTAGGATGG
TAAGTACAGAAAACTTCAAAAAAGTTAAGATTAGAGAAATATCCTTAGAGGAGGCTGTTACAGCATCTAA
TTACGAAGAAATTAACAAGCAGGTCACTAACAAAAAAATTGCTCTCCAGGCTCTTTTTCTTTCGATTGCT
AATCAAAAAGAGGATGTCGCCTTATATATATTATCTAATTTTGAGATAACTAGACAAGATGTTATTTCCA
TAAAGCATGAGTTGTATGATATTGAGTATCTACTTAGCGCTCATAATTCAAGCTGTAAAGTACTTGAGTA
TTTTATCAATAAGGGATTGGTTGATGTAAACACAAAGTTCAAAAAAACTAATAGTGGGGATTGTATGTTG
GATAACGCAATAAAATATGAGAATGCAGAAATGATAAAACTATTATTGAAATATGGTGCAACATCTGACA
ATAAATATATTTA
Protein Sequence 
>gi|74314886|ref|YP_313304.1| OspC1 [Shigella sonnei Ss046] MNISETLNSANTQCNIDSMDNRLHTLFPKVTSVRNAAQQTMPDEKNLKDSANIIKDFFRKTIAAQSYSRMFSQGSNFKSLNIAIDAPSDAKASFKAIEHLDRLSKHYISEIREKLHPLSAEELNLLSLIINSDLIFRHQSNSDLSDKILNIKSFNKIQSEGICTKRNTYADDIKKIANHDFVFFGVEISSHQKKHPLNTKHHTVDFGANAYIIDHDSPYGYMTLTDHFDNAIPPVFYHEHQSFLDKFSEVNKEVSRYVHGSKGIIDVPIFNTKDMKLGLGLYLIDFIRKSEDQSFKEFCYGKNLAPVDLDRIINFVFQPEYHIPRMVSTENFKKVKIREISLEEAVTASNYEEINKQVTNKKIALQALFLSIANQKEDVALYILSNFEITRQDVISIKHELYDIEYLLSAHNSSCKVLEYFINKGLVDVNTKFKKTNSGDCMLDNAIKYENAEMIKLLLKYGATSDNKYI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ospC1 mutants had reduced PMN transepithelial migration when compared to wild-type infection, PMN transepithelial migration is necessary for virulence of Shigella (Zurawski et al., 2006).
References
Zurawski et al., 2006: Zurawski DV, Mitsuhata C, Mumy KL, McCormick BA, Maurelli AT. OspF and OspC1 are Shigella flexneri type III secretion system effectors that are required for postinvasion aspects of virulence. Infection and immunity. 2006; 74(10); 5964-5976. [PubMed: 16988276].